Glutamine Metabolism Supports the Functional Activity of Immune Cells Against Aspergillus Fumigatus.

Daniela Antunes,Samuel M. Goncalves,Vasiliki Matzaraki,Claudia S. Rodrigues,Relber A. Goncales,Joana Rocha,Jorge Saiz,Antonio Marques,Egidio Torrado,Ricardo Silvestre,Fernando Rodrigues,Frank L. van de Veerdonk,Coral Barbas,Mihai G. Netea,Vinod Kumar,Cristina Cunha,Agostinho Carvalho

Microbiology spectrum（2023）

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摘要

The fungal pathogen Aspergillus fumigatus can cause severe and life-threatening forms of infection in immunocompromised patients. The reprogramming of cellular metabolism is essential for innate immune cells to mount effective antifungal responses.

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关键词

immunometabolism,glutamine,Aspergillus,macrophage,antifungal immunity

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