The Optimal State Scoring Tool: Guidance for Interdisciplinary Care of Infants with Severe Bronchopulmonary Dysplasia and Its Relation to Linear Growth
Journal of Perinatology(2023)
摘要
Objective Infants with severe bronchopulmonary dysplasia (sBPD) have complex medical courses. We developed the clinician-rated Optimal State Scoring Tool (OSST) that measures factors relevant to clinical improvement of sBPD and investigated preliminary validity using linear growth outcome and OSST scores in sBPD patients. Methods Tool development process and pilot findings are provided for 13 patients evaluated longitudinally. OSST scores, length measurements, and steroid dependency values were obtained. Changes in OSST scores and lengths were examined using linear mixed-effect models. Results OSST scores were significantly correlated with linear growth (95% CI 0.36, 0.57). The steroid-dependent group showed significantly slower rate of linear growth (95% CI 0.74, 1.05) and slower rate of increase in OSST scores (95% CI 0.99, 2.13) compared to the non-steroid-dependent group, with the OSST showing the largest effect size. Conclusion Pilot data reflect promising evidence for OSST construct validity in monitoring clinical outcomes in sBPD patients.
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关键词
Health care,Paediatrics,Medicine/Public Health,general,Pediatrics,Pediatric Surgery
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