Acharya Prafulla Chandra College, established in 1960, in West Bengal, India. It is affiliated West Bengal State University. The college is awarded grade "A" by National Assessment and Accreditation Council (NAAC).
Introduction/ Objective: Gut wellness is becoming the postulate of overall well-being that promotes digestion, immunity, and mental health. Although awareness among the population has increased, it is not matched with evidence-based practice, especially in Indian communities. The research aimed to assess the level of knowledge, perceptions, and behaviours on gut health with special attention to the integration of dietary supplements in two metropolitan cities in India, Mumbai and Chandigarh. Methods: A cross-sectional, questionnaire-based survey comprising a 20-item Likert-scale instrument was conducted; 110 participants participated. The questionnaire encompassed the gut health awareness, perceptions of diet therapy, and willingness to adopt supplements. Descriptive statistics, ANOVA, student t-tests, and Pearson correlation were employed using MINITAB 17. Results: The study revealed a moderate level of awareness of gut health concepts, with a high level of agreement in the roles of digestion, but limited knowledge of prebiotics and the diversity of the microbiome. A significant correlation was found between perceptions of gut health roles and functions of diet in gut health, with perceptions and willingness of supplement adoption (p = 0.000). We found no significant associations between knowledge level and demographic factors, with the exception of gender. Discussion: Results indicate that there is a gap in understanding and behaviour of gut health. Although awareness exists, there exist a lot of misconceptions, especially about the role of probiotics and dietary interventions.Conclusion Targeted educational programs and culturally relevant public health interventions are essential to bridge this gap and promote evidence-based use of supplements in urban India.
Proton beam therapy is a relatively new and alternative modality for cancer treatment. Its major advantage is the highly localised energy deposition of protons at a specific depth, enabling controlled damage to malignant tissues while sparing surrounding healthy cells. However, the successful application of this technique to a specific cancer site needs accurate modelling of several qualitative and quantitative parameters. These parameters are related to both the beam and the target anatomy. In this work, we investigate the suitability of proton beam therapy for the treatment of oesophageal cancer. We use a simulation-based workflow implemented with SRIM. The SRIM code and its TRIM module, enables detailed evaluation of proton energy loss profiles, penetration ranges, stopping powers, and Bragg peak localisation in multilayer tissue equivalent targets, which provides critical insight into energy deposition characteristics relevant for therapeutic optimisation.
The present investigation offers a novel approach by scientifically revalidating traditional beliefs surrounding the medicinal value of Bengal amloki (Phyllanthus emblica L.) through comprehensive physicochemical, spectroscopic and chromatographic analyses. This study aimed to determine the bioactive potential and establish traditional beliefs within the framework of scientific interpretation, and to characterize the physicochemical and spectroscopic properties of the fruits of Bengal amloki. The fruits' chemical analysis was done to assess their bioactive potential as a source of alternative medicine and their ability to treat ailments. The nutritious fruits of Bengal amloki (also known as amla or Indian gooseberry) revealed C, H, O and N contents of 48.773 +/- 0.211%, 4.858 +/- 0.222%, 42.411 +/- 0.447% and 1.844 +/- 0.057%, respectively. Based on Fourier Transform Infrared Spectroscopy (FTIR) results, strong bonds between C-O, O-H, N-H, O=C=O, C-H, and O-H molecules supported the presence of primary alcohol, carboxylic acid, alkene, carbon dioxide, alkane and phenol, respectively. Several significant bioactive phyto-constituents have also been detected by Gas chromatography-mass spectrometry (GC-MS) screening, whose bioactivities are believed to be useful in the management of various disorders. The results showed that biomass with high fixed carbon (FC), high volatile matter (VM) and low Compositional analysis (CA) had the best efficiency, antioxidant properties, and potential for converting energy.
Two new thiocyanato-bridged copper(ii) complexes of 1D polymeric chains of molecular formula [Cu(L1)(mu 1,3-NCS)]n (1) and [Cu(L2)(mu 1,3-NCS)]n (2) [HL1 = N-propyl-N-(5-bromosalcylidine)ethane-1,2-diamine; HL2 = N-propyl-N-(5-chlorosalcylidine)ethane-1,2-diamine] have been synthesized and characterized. Characterizations of 1 and 2 have been accomplished by several physicochemical techniques, including single crystal X-ray diffraction studies. X-ray diffraction analyses of 1 and 2 reveal that the monomeric units of the 1D polymers are bridged and interconnected via the mu 1,3-thiocyanato group. The coordination geometry around the Cu centers in 1 and 2 can be best described as a distorted square pyramidal environment. The current-voltage characteristics of the Al/1/ITO and Al/2/ITO structures have been analysed by considering the thermionic emission theory of the Schottky barrier diode. Employing a conventional method, the barrier height and ideality factor have been calculated to be 0.89 eV and 3.84 for 1, and 0.84 eV and 3.75 for 2, respectively. The series resistances have been obtained graphically as 4.24 x 103 Omega for Al/1/ITO and 2.65 x 103 Omega for Al/2/ITO structures using the modified Norde's technique. Both complexes 1 and 2 show moderate catecholase activity as observed by examining the oxidation of 3,5-di-tert-butylcatechol (3,5-DTBC) to 3,5-di-tert-butylquinone (3,5-DTBQ). Density functional theory (DFT) calculations, including HOMOs and LUMOs, were carried out to acquire the Fukui function values at the Cu centers in 1 and 2 to understand that the substrate 3,5-DTBC most likely binds with the Cu(ii) for its activation during the catalytic process. However, a comparative assessment of their catecholase activities indicates that 2 (kcat = 29.76 h-1) has superior catalytic efficacy in comparison to 1 (kcat = 11.15 h-1).
Background Stable bacterial lipases have become indispensable biocatalysts owing to their exceptional thermostability, catalytic efficiency, and tolerance to harsh industrial environments. Their expanding applications in biocatalysis, biodiesel production, bioremediation, enzyme engineering, and sustainable biotechnology have stimulated substantial scientific interest. However, a comprehensive bibliometric assessment of the intellectual structure, research evolution, and emerging trends in this field remains limited. Methods This study presents a comprehensive bibliometric analysis of global research on stable bacterial lipases published between 2010 and 2026. Bibliographic data were retrieved from the Lens.org database using a systematic Boolean search strategy and screened following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) framework. After applying predefined inclusion and exclusion criteria, 499 peer-reviewed journal articles were selected for analysis. Performance analysis and science mapping were conducted using the Bibliometrix/Biblioshiny package in R and VOSviewer (version 1.6.20) to evaluate publication trends, citation patterns, leading journals, authors, institutions, countries, collaboration networks, keyword co-occurrence, co-citation relationships, bibliographic coupling, and thematic evolution. Results The dataset comprised 499 journal articles published in 139 sources between 2010 and 2026, involving 2,322 authors with an average of 5.35 co-authors per document. The field exhibited a positive annual publication growth rate of 3.74%, indicating sustained expansion over the study period. The publications accumulated an average of 57.23 citations per document and collectively cited 42,878 references, demonstrating the maturity and scientific influence of the research area. Temporal and thematic analyses revealed increasing attention to enzyme stability, protein engineering, immobilization, biocatalysis, biodegradation, biodiesel production, and environmentally sustainable industrial applications. Network analyses further identified the major research clusters, collaborative patterns, and emerging thematic directions shaping the evolution of the field. Conclusions This study provides a comprehensive overview of the global scientific landscape of stable bacterial lipase research from 2010 to 2026. The findings highlight the growth, intellectual foundations, and emerging research priorities of the field while providing valuable insights for researchers, industrial practitioners, and policymakers seeking to advance enzyme biotechnology and sustainable bioprocess development.
