Beulah Heights University is a not for profit, private institution offering higher education in Atlanta, Georgia. The university was established in 1918 and is accredited to Association for Biblical Higher Education and Transnational Association of Christian Colleges and Schools. Formally, the university was affiliated with the Christian-Interdenominational religion. Beulah Heights is approved by the State of Georgia Nonpublic Postsecondary Education Commission for granting of Associate of Arts (AA), Bachelor of Arts (BA), Master of Arts (MA), Master of Business Administration (MBA), Master of Divinity (M.Div.), Doctor of Ministry (DMin), and Doctor of Philosophy (PhD) degrees.
Introduction: The incidence of Large Vessel Occlusion-Acute Ischemic Stroke (LVO-AIS) continues to increase in young adults. Although young adults who undergo mechanical thrombectomy have favorable outcomes, it is unclear if stroke etiology affects rehabilitation outcomes & discharge destination for these patients. Hypothesis: Large artery atherosclerosis (LAA) results in worse outcomes as compared to other etiologies in terms of discharge destination. Methods: This retrospective study cohort comprised of patients 18-50 years of age, presenting to the Cleveland Clinic Stroke Enterprise, with LVO-AIS from January 2017 to December 2021. Patients with LVO on CTA or MRA at presentation were included. We then assessed patients with LAA and compared their discharge destination to patients with other etiologies. Results: Out of 1210 patients with AIS, 172 with LVO were included. 31 patients (18%) had stroke etiology as Large Artery Atherosclerosis (per TOAST criteria). Among patients with LAA, the median initial NIHSS was 6 and median discharge NIHSS 4. 16.2% of these patients received IV thrombolysis and 32.4% underwent mechanical thrombectomy (MT). 48.4% patients were discharged to acute rehabilitation, 32.3% went home, 12.9% SNF, and 6.5% deceased. In contrast, patients for whom TOAST criteria was not “Large Artery Atherosclerosis”, had a median initial NIHSS 9 and median discharge NIHSS 2. 31.2% received IV thrombolysis and 43.9% underwent MT. Their discharge destination was home for 56%, acute rehabilitation for 27.7%, LTAC for 5%, 2.8% SNF, and 8.5% deceased. Both these groups had similar initial mRS. Conclusions: Young adults with LVO-AIS had good outcomes irrespective of stroke etiology, however LAA patients were less likely to be discharged home compared to other etiologies, likely owing to less functional recovery as compared to other etiologies. Further studies are needed to determine why young adults with LVO with LAA have worse outcomes.
Genetic diversity, heritability, the genetic advance of yield, and associated traits are some important criteria to generate some basic information related to the genetic improvement of crops. Some characters of Sechium edule (Jacq.) Sw. genotype fruits have been evaluated for their improvement purpose. Genotypes and fruit samples of Sechium were randomly collected for fruit traits such as length (FL), width (FW), circumference/girth (FC), and the number of ridges (FR) from the various parts of village Kigwema of Kohima district, Nagaland at a mean value of latitude (25.60690 N), longitude (94.34250 E) and altitude (1538 masl) for the purpose. Genotypes and fruit samples collection for trait study normally distributed in histogram plot and normality test. Analysis of variance (ANOVA) estimated significant differences in fruit sample traits. The phenotypic coefficient of variation (PCV) was greater than the genotypic coefficient of variation (GCV) for all the traits. The phenotypic and genotypic coefficient of variation was recorded maximum for trait fruit length, while maximum heritability was recorded for trait fruit circumference. High heritability and high genetic advance estimates for fruit circumference suggest that it could be considered for further improvement through various breeding programs. Principle component analysis (PCA) showed that fruit length and fruit ridges numbers are responsible for most of the variations observed in the fruit morphology and could be considered for its improvement. Fruit width recorded maximum for correlation coefficient direct value indicated towards effect on the fruit circumference and direct selection of the trait for its improvement.
1 Cleveland Heights, Ohio 2 Division of Colon and Rectal Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin Funding/Support: None reported. Financial Disclosure: None reported. Correspondence: Kirk A. Ludwig, M.D., Medical College of Wisconsin, 9200 West Wisconsin Ave, Milwaukee, WI 53226. Email: [email protected]
Directed and produced by Reed Dan. Premiered at the 2019 Sundance Film Festival on January 25, 2019. Broadcast on HBO Network in two parts, March 3-4, 2019. In this three hour and 56-minute documentary, Dan Reed tells a story through the eyes of two men, Wade Robson (born in Brisbane, Australia)
Caroline Kepnes, New York: Simon & Schuster, New York, 2014. 464 pp. $17.00 Screenplay by Greg Berlanti, Sera Gamble, April Blair, Michael Foley, Neil Reynolds, Adria Lang, Amanda Zetterstrom, Caroline Kepnes, Kelli Breslin. Directed by Lee Toland Krieger, Marcos Siega, Vic Mahoney, Marta
