Aktualisierungshinweis Die DDG-Praxisempfehlungen werden regelmäßig zur zweiten Jahreshälfte aktualisiert. Bitte stellen Sie sicher, dass Sie jeweils die neueste Version lesen und zitieren.
Die Praxisempfehlungen der Deutschen Diabetes Gesellschaft (DDG) zusammen mit der Deutschen Gesellschaft für Innere Medizin (DGIM) lehnen sich eng an die Inhalte der Nationalen VersorgungsLeitlinie (NVL) "Therapie des Typ-2-Diabetes" an. Die in diesen Praxisempfehlungen abgebildeten Inhalte sind zum großen Teil die konsentierten Abschnitte der ganzen Arbeitsgruppe, die für die Erarbeitung der Nationalen VersorgungsLeitlinie verantwortlich war. Umfangreiche Details einschließlich der wissenschaftlichen Belege finden Sie in der Langfassung der NVL (http://www.versorgungsleitlinien.de).
Abstract Aim This study aims to assess the reliability and overall quality of publicly accessible video content related to orthognathic surgery on two major social media platforms: TikTok™ and YouTube™. Method A total of 320 videos were systematically analyzed on TikTok™ and YouTube™ using the search terms “jaw surgery” and “orthognathic surgery.” Data collection was carried out between March and April 2024. Each video was evaluated using the Global Quality Score (GQS) to determine general content quality and a modified version of the DISCERN instrument to assess reliability. Video reliability was assessed using the DISCERN instrument, a standardized tool for evaluating the quality of health information. Additional parameters, including video duration, view count, number of likes, comments, and uploader type were recorded and analyzed. All searches were performed in incognito mode without VPN to minimize algorithmic bias and ensure reproducibility. Results For the ‘jaw surgery’ term, statistically significant associations were observed between uploader type and platform (p < 0.05): patients were the predominant uploaders on TikTok, whereas doctors and clinics were more common on YouTube. Comparative analyses demonstrated that GQS and DISCERN scores were comparable between platforms, with TikTok showing slightly higher mean scores for the ‘Orthognathic Surgery’ term, though these differences were not statistically significant (p > 0.05). YouTube videos were longer in duration for certain comparisons, whereas TikTok videos received significantly higher engagement metrics (views, likes, comments, and subscriber counts) (p < 0.05). Conclusion The content about orthognathic surgery on both platforms was found to be of poor to moderate quality (mean GQS: 1.40–2.49 out of 5) and limited reliability (mean DISCERN: 0.81–2.21 out of 4), with significant variation between search terms and platforms. Clinical trial number This study did not involve human participants, identifiable personal data, or experimental interventions. All analyzed material consisted of publicly accessible online videos, which are exempt from institutional review board approval according to relevant guideline (e.g., the Declaration of Helsinki and local regulations). Therefore, ethical approval was not required and was not sought.
Background:Local anesthetic solutions containing epinephrine are widely used in oral surgery to prolong anesthesia and improve hemostasis; however, their sympathomimetic effects may influence cardiovascular parameters. Evidence comparing different epinephrine concentrations in articaine during third-molar surgery remains limited. This randomized clinical trial compared the cardiovascular effects and clinical performance of 4% articaine with epinephrine 1:100,000 (A100) and 1:200,000 (A200) during mandibular third-molar extraction. Material and Methods:A prospective, randomized, split-mouth, double-blind clinical trial was conducted in 40 healthy patients undergoing bilateral impacted mandibular third-molar extraction. Each participant received A100 on one side and A200 on the contralateral side in randomized order with a 15-day interval. Heart rate (HR), blood pressure (BP), and oxygen saturation (SpO2) were recorded at baseline, immediately after injection, and at 5 and 15 minutes. Intraoperative bleeding, pain (VAS), and need for supplemental anesthesia were also assessed. Paired statistical tests were applied ( = 0.05). Results:Eighty procedures were analyzed. Intraoperative bleeding incidence was similar between A100 (10%) and A200 (12.5%) (p = 1.000). Supplemental anesthesia was required in 3.8% of procedures, with no difference between concentrations (p = 1.000). HR increased with both formulations but was significantly higher with A100 at 5 and 15 minutes (p = 0.035 and p = 0.003). BP showed no significant differences at any time point. SpO2 remained within normal limits, with slightly higher values for A200 at intermediate times. Pain scores did not differ significantly. Conclusions:Both epinephrine concentrations in 4% articaine provided comparable anesthetic efficacy and hemostasis with minimal cardiovascular effects in healthy patients undergoing mandibular third-molar extraction. The 1:200,000 concentration produced a smaller heart-rate increase, suggesting a potential advantage in patients with cardiovascular risk, while 1:100,000 remains suitable when greater vasoconstriction is desired.