DSV A/S is a Danish transport and logistics company offering transport services globally by road, air, sea and train. Since its foundation in 1976 by nine independent Danish hauliers, the company has achieved rapid expansion and international presence, predominantly through a series of strategic competitor acquisitions, some of the most important ones being Samson Transport (1997), DFDS Dan Transport Group (2000), J.H.Bachmann (2004), Frans Maas (2006), ABX LOGISTICS (2008) and UTi Worldwide, Inc. in 2016. In April 2019, DSV signed an agreement to acquire Panalpina Welttransport (Holding) AG and the deal was closed in August 2019.With headquarters in Hedehusene (near Copenhagen), Denmark, and offices in more than 80 countries, DSV employs 56,000 people and collaborates with partners and agents globally. The company is listed on NASDAQ OMX Copenhagen (Copenhagen Stock Exchange) and included in the OMXC25 index as one of the 25 most traded stocks.The company is structured in three divisions, Road, Air & Sea, and Solutions. Its main activities lie within road transport (trucking) networks in Europe, North America and South Africa, and its global air and sea freight forwarding business. The group also has a growing contract logistics business. As part of an asset-light financial strategy to maintain fixed costs at a minimum and be able to quickly respond to market fluctuations, the group does not own any ships or aeroplanes and only a relatively small number of trucks and trailers.Jens Bjørn Andersen became CEO in August 2008. In 2020, the company reported a net revenue of DKKm 115,932.H.
Mass manufacturing which created millions of jobs in the twentieth century has unfortunately caused damage to the environment. The emergence of remanufacturing is seen as a rescuer which has allowed the life cycle of products to be extended by remaking the failed products so that they become as good as new and continue to be reused until they cannot be repaired or remanufactured. In this context, vehicle remanufacturing has become an important field, and as a result the remanufacturing of different vehicle parts is being widely studied and applied. Among the many remanufacturing technologies, the emerging Additive Manufacturing (AM) technology is becoming very popular and is being adopted by more and more enterprises and integrated into the remanufacturing layout. This study discusses the situation of vehicle remanufacturing globally and while it finds that the market size of vehicle part remanufacturing in many countries is very large, in Europe the scale exceeds 20
In the dominant livestock systems of Sahelian countries herds have to move across territories. Their mobility is often a source of conflict with farmers in the areas crossed, and helps spread diseases such as Rift Valley Fever. Knowledge of the routes followed by herds is therefore core to guiding the implementation of preventive and control measures for transboundary animal diseases, land use planning and conflict management. However, the lack of quantitative data on livestock movements, together with the high temporal and spatial variability of herd movements, has so far hampered the production of fine resolution maps of animal movements. This paper proposes a general framework for mapping potential paths for livestock movements and identifying areas of high animal passage potential for those movements. The method consists in combining the information contained in livestock mobility networks with landscape connectivity, based on different mobility conductance layers. We illustrate our approach with a livestock mobility network in Senegal and Mauritania in the 2014 dry and wet seasons.
A spatially and temporally heterogeneous environment may lead to unexpected population dynamics, and knowledge still is needed on which of the local environment properties favour population maintenance at larger scale. As regards pathogen vectors, such as tsetse flies transmitting human and animal African trypanosomosis, such a knowledge is crucial for proposing relevant management strategy. We developed an original mechanistic spatio-temporal model of tsetse fly population dynamics, accounting for combined effects of spatial complexity, density-dependence, and temperature on the age-structured population, and parametrized with field and laboratory data. We confirmed the strong impact of temperature and adult mortality on tsetse populations. We showed that patches with the lowest mean temperatures and lowest variations act as refuges when adult mortality is homogeneously increased. Our results highlighted the importance of baseline data collection to characterize the targeted ecosystem before any control measure is implemented to maximize its efficiency.
Purpose of Study: A sarcoidosis treatment guidleine is being developed by a European Respiratory Society (ERS) working group. The sarcoidosis support groups were asked to provide input regarding what outcomes were most important to the patient. Methods: Sarcoidosis support groups in collaboration with the European Lung Foundation developed an outcome survey that was translated into six languages. Individual outcomes were given overall titles and defintiions for each outcome were provided. Patients were asked to rank each outcome on a 5 point scale from 1 (extremely important) to 5 (not important at all). Results: To date, 778 individuals have completed the survey in their native langauge: 270 German, 158 English, 147 Italians. 112 Dutch, 73 Spanish, and 8 French using an online survey. The eight outcomes and scores were: quality of life (1.41); Functionality (1.43); Survival (1.69); Imaging (1.84); Adverse events (1.86); Blood tests (1.98); Pulmonary function tests (2.06). All outcomes ranged from Extremely important (1) to Very important (2). Of the outcomes, quality of life and functionality were the most important, while blood tests and pulmonary function tests were less important outcomes. Imaging was ranked as a more important outcome than blood or pulmonary function tests. Conclusion: Sarcoidosis patients ranked treatments which improved quality of life and functionality as most important outcomes. Patients ranked adverse events as a less important outcome than quality of life, survival, and functionality.
Pseudomonas putida BIRD-1 has the potential to be used for the industrial production of butanol due to its solvent tolerance and ability to metabolize low-cost compounds. However, the strain has two major limitations: it assimilates butanol as sole carbon source and butanol concentrations above 1% (v/v) are toxic. With the aim of facilitating BIRD-1 strain design for industrial use, a genome-wide mini-Tn5 transposon mutant library was screened for clones exhibiting increased butanol sensitivity or deficiency in butanol assimilation. Twenty-one mutants were selected that were affected in one or both of the processes. These mutants exhibited insertions in various genes, including those involved in the TCA cycle, fatty acid metabolism, transcription, cofactor synthesis and membrane integrity. An omics-based analysis revealed key genes involved in the butanol response. Transcriptomic and proteomic studies were carried out to compare short and long-term tolerance and assimilation traits. Pseudomonas putida initiates various butanol assimilation pathways via alcohol and aldehyde dehydrogenases that channel the compound to central metabolism through the glyoxylate shunt pathway. Accordingly, isocitrate lyase - a key enzyme of the pathway - was the most abundant protein when butanol was used as the sole carbon source. Upregulation of two genes encoding proteins PPUBIRD1_2240 and PPUBIRD1_2241 (acyl-CoA dehydrogenase and acyl-CoA synthetase respectively) linked butanol assimilation with acyl-CoA metabolism. Butanol tolerance was found to be primarily linked to classic solvent defense mechanisms, such as efflux pumps, membrane modifications and control of redox state. Our results also highlight the intensive energy requirements for butanol production and tolerance; thus, enhancing TCA cycle operation may represent a promising strategy for enhanced butanol production.
