The Liaquat National Hospital (LNH), is located at Stadium Road, Karachi, Sindh, Pakistan.
Chronic kidney disease (CKD) is a significant contributor to stroke-related mortality. Stroke risk increases in a stepwise manner as kidney function declines. However, trends of death rate due to stroke among individuals over 45 years of age with CKD have not been well described. The aim of this study is to evaluate stroke-related mortality among adults aged ≥ 45 with CKD in the United States. Utilizing the CDC WONDER database, death certificates were examined from 1999 to 2023 for stroke-related mortality in adults with CKD aged ≥ 45 years. Age-adjusted mortality rates (AAMR) per 100,000 individuals, annual percentage changes (APC), average annual percent changes (AAPC), and 95
Non-alcoholic fatty liver disease (NAFLD) and diabetes mellitus (DM) are increasingly prevalent, interrelated conditions contributing significantly to morbidity and mortality. Understanding long-term mortality trends is essential to guide public health strategies. This study aimed to evaluate nationwide mortality trends involving NAFLD and DM in the United States from 1999 to 2022 and to assess demographic and geographic disparities. CDC WONDER was used to extract data for adults aged ≥ 25 years. 10th Revision (ICD−10), using the explicit codes with K74.0, K74.6, K75.8, K76.0 and K76.9 for NAFLD and E10-E14 for DM. Age- Adjusted Mortality Rates (AAMRs) per million population were calculated and trends were analyzed by calculating annual percent change (APC) and the average annual percent change (AAPC) using Joinpoint Regression Program (version 5.2.0.0; National Cancer Institute), with statistical significance set at p < 0.05. From 1999 to 2022, a total of 126,431 NAFLD and DM related deaths were recorded with most of the deaths occurring in Medical Facilities (43.52
Sleep deprivation is commonly reported among health care professionals due to irregularity in duty hours which may affect neurocognitive functions. The current study aimed to determine the prevalence of Shift Work Sleep Disorder (SWSD) and its association with cognitive levels among young physicians working in shifts in various health care departments. This cross-sectional survey was conducted in various tertiary care hospitals of Karachi, Pakistan. Data from 230 young doctors were collected through purposive sampling. The International classification of sleep disorders (ICSD-2) based questionnaire and the Pittsburgh Sleep Quality Index (PSQI) was used to diagnose SWSD while the Mini Mental State Examination (MMSE) Scale was used for cognitive status. Both the scales have a high reliability coefficient showing good internal consistency. Association of SWSD and MMSE was analyzed using logistic regression model. The mean age of the sample was 26.15 ± 2.4 years with 131 females on board. The prevalence of SWSD was found to be 59
Primary caregivers of critically ill ICU patients experience substantial psychological stress, yet this burden remains understudied in lower middle-income countries such as Pakistan. This study assessed the magnitude and predictors of perceived stress among primary family caregivers of patients admitted to medical and surgical ICUs at three tertiary care hospitals in Karachi. A cross-sectional study was conducted among 161 primary caregivers at Jinnah Postgraduate Medical Center, Civil Hospital Karachi, and Liaquat National Hospital. Data were collected through interviews using the Perceived Stress Scale (PSS-10; range 0–40). Ethical approval and informed consent were obtained. Univariable multinomial logistic regression identified factors associated with stress levels, followed by multivariable multinomial logistic regression including significant or clinically relevant predictors. Overall, 65.8
The coronavirus disease (COVID-19) pandemic has profoundly impacted mental health worldwide, exacerbating anxiety and depression, and influencing adherence to public health measures. To measure the frequency and demographic determinants of anxiety, depression, and emotional contagion among Egyptians during the pandemic from May to August 2020. The study employed a cross-sectional web-based survey that specifically targeted 666 Egyptians from four different regions. A validated Arabic questionnaire was used to assess anxiety using the Generalized Anxiety Disorder-7 (GAD-7) scale, depression using the Patient Health Questionnaire-9 (PHQ-9), and emotional contagion using the Emotional Contagion Scale (ECS), along with demographic variables. Anxiety (GAD ≥ 5) was observed in 66.7
