Pelita Harapan University (Indonesian: Universitas Pelita Harapan, UPH) is a private Evangelical coeducational higher education institution run by the Pelita Harapan Education Foundation (Indonesian: Yayasan Pendidikan Pelita Harapan) in Lippo Village, Tangerang, Banten, Indonesia. It was founded in 1993. UPH was the first university in Indonesia to introduce programs entirely taught in English, the first to offer a liberal arts curriculum, and the first to introduce a multi-disciplinary approach to its programs.
PurposeFamily businesses in emerging economies often face challenges in achieving growth while preserving their cultural and ethnic identities. This study examines the influence of inclusivity on business expansion in family-owned micro-, small- and medium-sized enterprises (MSMEs) with cultural awareness, familiness and local coopetition as mediating factors.Design/methodology/approachA quantitative survey was conducted with 300 family entrepreneurs in North Sumatra, Indonesia, a region known for its diverse indigenous ethnic communities. The proposed model was analyzed using partial least squares structural equation modeling (PLS-SEM) to test the hypotheses.FindingsInclusivity enhances cultural awareness, which strengthens family business governance and identity as key dimensions of familiness. Cultural awareness mediates the relationship between inclusivity and familiness, whereas local coopetition, although not directly driven by governance or identity, significantly promotes business expansion.Practical implicationsFamily companies and local governments should foster inclusivity and cultural awareness to support socioemotional wealth and adopt coopetition strategies for sustainable longevity.Social implicationsThis study highlights the role of family firms as community anchors that support collaboration in multicultural settings. Thus, they can strengthen their social cohesion and preserve their local cultural values while pursuing economic growth.Originality/valueThis study extends the familiness theory by embedding inclusivity and cultural awareness as antecedents while clarifying the relational boundary conditions of coopetition in multiethnic family MSMEs.
Thrombosis is a major cause of cardiovascular diseases, contributing significantly to global mortality rates. It has become necessary to develop more cost-effective and safer treatments for thrombosis, such as those derived from plants, due to prohibitively high costs and severe side effects of existing medications. Ginger (Zingiber officinale) has been reported to have thrombolytic abilities via fibrinolysis in vitro. Subsequently, the in silico studies described herein aimed to further understand the fibrinolytic mechanisms of zingibain-2 at the molecular level through molecular docking and dynamics simulations. AlphaFold3 accurately predicted the zingibain-2 structure and stably predicted the fibrin peptide-zingibain interactions. A preference for proline at the P2 position, typical of cysteine proteases, was found in 18, 8-residue peptides screened from human fibrin chains (PDB: 2HLO). Protein superimposition between the AlphaFold3 prediction and X-ray crystallography structures showed a minimum root mean square deviation value of 0.33 & Aring; and 97.72% favorable residue orientation on a Ramachandran plot. Initial docking identified 13 out of 18, 8-residue human fibrin peptides with short catalytic distances. However, GROMACS molecular dynamics simulations of these AlphaFold3-docked complexes over 100 ns further narrowed this down to 11 out of 18, 8-residue human fibrin peptides with stable interactions, as demonstrated by their reliably short catalytic distances and negative binding energy. These stable models showed close, stable interactions with zingibain-2, and thus, support its potential as a plant-based thrombolytic agent. However, this must be experimentally validated.
Objectives: Sexual violence remains widely underreported, often described as the "tip of the iceberg,"due to survivors' fear, stigma, and uncertainty about seeking help. Although reporting rates in Indonesia have increased, the processes through which survivors decide to seek support remain insufficiently understood. This study aimed to explore the decision-making experiences of survivors of sexual violence in seeking help. Methods: A qualitative descriptive design was employed using purposive sampling. Participants were survivors of sexual violence who had sought help and had been screened for post-traumatic stress disorder (PTSD). Data were collected through in-depth interviews and analyzed using thematic analysis. Results: Seven interrelated themes emerged, including the chronological context of sexual violence experiences, survivors' initial ignorance of sexual violence, multidimensional life changes following trauma, self-denial after sexual violence, decision-making processes driven by the refusal to fall into depression, the role of support from trusted individuals, and survivors' experiences after seeking help. Conclusion:This study highlights the complexity of survivors' help-seeking decision-making and underscores the importance of trauma-informed and culturally sensitive mental health nursing care. Strengthening community education on sexual violence, supporting families in responding appropriately to disclosure, and developing targeted nursing interventions may facilitate survivors' recovery and engagement with professional services. Future research should further examine factors influencing help-seeking and evaluate the effectiveness of nursing interventions for survivors experiencing PTSD.
Student competency assessment is a pillar of education, as it is necessary to determine students' learning needs, including clinical judgment skills. This study aimed to compare self-rated clinical judgment assessment results from students with those of their preceptors using the Indonesian version of the Lasater Clinical Judgment Rubric (LCJR-INA). The research employed a comparative quantitative study design involving 210 final-stage students actively enrolled in the nursing program at a university in Indonesia, using purposive sampling. The instrument used was the LCJR-INA. Clinical judgment scores were compared using the Wilcoxon signed-rank test, and to account for the nested data structure of students within preceptors, a linear mixed-effects model with a random intercept for preceptors was applied. The results reveal a significant difference between student and preceptor scores, with students rating their clinical judgment abilities higher than their preceptors. Preceptor scores were not significantly related to student self-assessment scores, and a sensitivity analysis using linear regression yielded similar results. A combination of assessments by both preceptors and students is recommended to provide a more realistic representation of students ' clinical judgment and to help preceptors identify additional support for students.
This study aims to analyze the strategic leadership model, business model innovation, and product innovation to improve performance of State-Owned Business Enterprise. This study employed a quantitative research method and reported the results of a survey using a questionnaire with a population of 28 SOEs in Indonesia engaged in the food and fertilizer industry. Analysis was carried out using SmartPLS software, which consists of descriptive statistics, measurement model evaluation, structural model evaluation, and hypothesis testing. Results of this study indicate that influence of strategic leadership is significant on business model innovation. The influence of business model innovation is significant on product innovation and on company performance. However, influences of strategic leadership on company performance and product innovation are not significant, and influence of product innovation on company performance is also not significant. Strategic leadership has a significant impact on the decision-making process, thus it can facilitate organizations to implement effective strategies designed to achieve optimal performance. Companies that implement strategic leadership have potential to improve performance through the implementation of good planning, motivating, directing, developing employee capabilities in product innovation and business model innovation, as well as communicating company's long-term vision or goals. (c) 2026 by the authors; licensee Growing Science, Canada