Rampurhat Government Medical College and Hospital(RPHGMCH) is a full-fledged tertiary referral Government Medical college. It was established in the year 2018. The college imparts the degree Bachelor of Medicine and Surgery (MBBS). Nursing and para-medical courses are also offered. The college is affiliated to West Bengal University of Health Sciences and is recognised by the National Medical Commission. The hospital associated with the college is one of the largest hospitals in the Birbhum district. The selection to the college is done on the basis of merit through National Eligibility and Entrance Test. Yearly undergraduate student intake is 100 from the year 2019. The medical college is divided into two campuses, main campus beside SH 14(District Hospital, Super Speciality Hospital, Academic Block, Girls' Hostel, Boys' Hostel, Intern & PGT Hostels) and the other at Chowk Mandala (Boys' Hostel & Staff Quarters)..
The overuse of antibiotics without medical prescription is a major public health concern, leading to bacterial resistance that causes severe infections and increases global mortality. This study aimed to determine the prevalence and identify the main risk factors of antibiotic self-medication among patients admitted to the emergency department. This cross-sectional, descriptive, and analytical study was conducted over a five-month period (July to November 2024) among patients aged 18 years and older admitted to the emergency department. We collected sociodemographic data, data on self-medication practices, and data on access to care. Multivariable logistic regression was applied to identify independent factors associated with antibiotic self-medication. The prevalence of antibiotic self-medication among participants was 77.7
Cefiderocol (FDC) shows promise against carbapenem resistance, with differing carbapenemase epidemiology across Southeast and East Asia, including India. This study evaluated the susceptibility of carbapenem-resistant Klebsiella pneumoniae (CRKP) and carbapenem-resistant Acinetobacter baumannii (CRAB) against FDC and assessed carbapenemase genetic influences on susceptibility. A total of 100 clinical isolates of CRAB and 100 clinical isolates of CRKP were studied. The minimum inhibitory concentration for FDC, ceftazidime-avibactam (CZA), aztreonam, polymyxins in CRKP, and polymyxins and minocycline in CRAB was determined by the broth microdilution method. Carbapenemases were detected using the ethylenediaminetetraacetic acid-modified carbapenem inactivation method in CRKP and the modified Hodge test for CRAB. The confirmation of carbapenemases (blaSME, blaNMC, blaGES, blaKPC, blaIMP, blaVIM, and blaNDM for all; blaOXA-48 in CRKP; and blaOXA-23 like blaOXA-24/40 and blaOXA-58 in CRAB) was performed by multiplex PCR. FDC resistance in CRKP and CRAB was 1% and 6%, respectively. CRKP isolates showed significant resistance to polymyxin B (31%), colistin (21%), aztreonam (34%), and CZA (41%; p < 0.05) as compared to FDC, while CRAB isolates exhibited higher FDC resistance (p < 0.05). Moreover, 96% of CRKP and 100% of CRAB were carbapenemase producers. For CRKP, blaOXA-48 + blaNDM combination and for CRAB, blaNDM was significantly associated with FDC resistance. The study revealed the presence of blaNDM as one of the causes for reduced susceptibility to FDC in these isolates.
Objectives: The integration of theory and practice is a cornerstone of the competency-based medical education (CBME) curriculum, necessitating innovative teaching–learning methods to bridge the gap between knowledge acquisition and its practical application. This analytical study aimed to evaluate the effectiveness of the flipped classroom approach in reinforcing pharmacology concepts among second-professional MBBS students at ESIC Medical College, Joka, India. Materials and Methods: A total of 101 Phase 2 MBBS students were randomly divided into two groups: One receiving traditional tutorials and the other participating in flipped classroom sessions. Topics covered included drugs used in peptic ulcer disease and antiemetic drugs. A validated questionnaire, comprising multiple-choice and short-answer questions, was administered before and after the intervention to assess knowledge retention. Results: Baseline pre-test scores showed no significant differences between the groups. However, post-test analysis revealed a statistically significant improvement in the flipped classroom group ( p = 0.02), indicating enhanced learning outcomes compared to the traditional tutorial group. Conclusion: The flipped classroom method demonstrated superior effectiveness in reinforcing pharmacological concepts among undergraduate medical students, as evidenced by statistically significant post-intervention improvements. These findings suggest that flipped classroom-based teaching can be a valuable addition to the CBME framework, promoting deeper understanding and application of theoretical knowledge in clinical contexts.
Introduction: Hypertension’s impact on global health is vast, yet its link to Indian pulmonary function remains unclear. Despite maintaining controlled blood pressure, hypertensive individuals may harbour undetected pulmonary deficits, necessitating a closer look at the intersection of cardiovascular and respiratory health. Aim: To compare spirometric parameters between subjects with controlled essential hypertension and normotensive healthy controls in Eastern India. Materials and Methods: A cross-sectional study was conducted at Rampurhat Government Medical College and Hospital of eastern India from April to December 2024. Total 84 non-smoking participants {42 controlled essential hypertensives (≥1 year duration), 42 normotensive} aged 18-60 years underwent spirometric evaluation. Spirometric parameters like Forced Vital Capacity (FVC), Forced Expiratory Volume in 1 second (FEV1), FEV1/FVC ratio, Forced Expiratory Flow 25-75% (FEF25-75%) and Peak Expiratory Flow Rate (PEFR) were measured using standardised American Thoracic Society (ATS)/European Respiratory Society (ERS) protocols. Data were statistically analysed by using Mann-Whitney U test. Results: Participants were middle-aged adults, with a mean age of 43.38 years including both the genders. However, hypertensive participants were significantly older (50.6±8.81 vs. 36.17±15.03 years, p<0.0001) with higher Mean Arterial Pressure (MAP) (103.43±8.79 vs. 88.93±6.09 mmHg, p<0.0001). All spirometric parameters except FEV1/FVC ratio were significantly impaired in hypertensives: FVC (68.52±12.77% vs. 100.6±15.69% predicted, p<0.0001), FEV1 (71.17±16.93% vs. 107.12±14.62% predicted, p<0.0001), PEFR (44.86±28.04% vs. 95.57±32.7% predicted, p<0.0001), and FEF25-75% (57.57±43.42% vs. 100.4±35.5% predicted, p<0.0001). Abnormal spirometric patterns occurred in 83.3% of hypertensives versus 9.5% of controls (OR=47.5, p<0.0001), with mixed defects predominating (59.5%). Strong negative correlations existed between MAP and spirometric indices (ρ=-0.75 for MAP-FVC). Conclusion: The present study findings indicated that controlled essential hypertension significantly impairs lung function in Eastern Indians, necessitating routine spirometry for comprehensive risk assessment.
