Sivanthi Aditanar College

This investigation comprises with the spectral, electronic and oligomeric scaffold modelling of 2-vinyl naphthalene (1[2VN]). The normal mode vibrational characteristic nature of the system has been studied using experimental FT-IR and FT-Raman spectra along with simulated vibrational compliments using B3LYP/6-31 + G(d,p). The FT-IR and FT-Raman spectrums have been recorded in the range of 4000–400 cm−1 and 4000–50 cm−1 respectively. The Potential energy distribution (PED) of 1[2VN] deepen the understanding on different modes of vibrations promoted by individual wavenumber. The experimental UV–Visible spectra was recorded within the region of 400–200 nm and correlated with calculated spectra by solvated TD-DFT B3LYP/6-31 + G(d,p) model. The calculated equilibrium structure has been compared with experimentally available structure and the chemical bonding nature was characterized using natural bond orbital (NBO) analysis. Thermodynamic properties such as heat capacities, entropies, enthalpies and their associations with temperature rise have been investigated. The frontier molecular orbital analysis (FMO), molecular electrostatic potential (MEP) and hyperpolarizability were investigated. In addition, the oligomer forms of 1[2VN] were constructed and around 19 scaffold candidates designed by substituting several donor acceptor moieties at different position to get a candidate with minimized the band gap. The geometry, FMO, MEP, NBO and selected NLO properties has been explored to identify the high efficient donor-pi-acceptor system.

Plants are used medicinally in different countries and are a source of many potent and powerful drugs. The antimicrobial activities of plant extracts may reside in a variety of different components. The beneficial medicinal effects of the plant materials typically result from the combinations of secondary product present in the plant.Medicinal and spice plants are renewable raw materials. Their production is an alternative to the overproduction of traditional crops in agriculture. They also have an increasing economic importance. Spices can be defined as any dried, fragrant, aromatic or pungent vegetables or plant substances in whole, broken or ground form that contribute flavour, whose primary function in food is seasoning rather than nutrition and that may contribute relish or piquancy of foods and beverages. . In this Present Study the bioactive compounds from the plant Piper nigrum L. were determined by using FT-IR Spectroscopic methods.

Plants are more important in human life and fulfill his every day needs. In recent developments free radicals are involved in many diseases. The World Health Organization [WHO] has adopted a major policy change wherein most developing nations have to make use of more traditional medical practices for primary health care. The Indian traditional system of medicine has identified the leaves with digestive and pancreatic lipase stimulant activities Piper longum L. leaves are used in eye drops for eye injury or infection as a baby lotion for the new born, for coughs, asthma, and constipation and to arrest milk secretion. Essential oil from leaves of this plant has been used for the treatment of respiratory catarrhs and antiseptic. Piper betle L. showed hypotensive, Cardio tonic, smooth and skeletal muscles relaxant actions. This present study raveled to determine the bioactive compounds from the Piper longum L.

The Piper betle L. plant materials such as [leaf and seed] were collected and allowed to shade dry to remove moisture content. The dried samples were used for further studies. The powdered plant materials were filled separately in the thimble and extracted successively using a soxhlet extractor with distilled water, acetone, chloroform, DMSO, ethanol and aqueous. All the extracts were subjected to systematic phytochemical screening for the presence of phytochemical constituents. Carbohydrates, Amino Acids, Proteins, Chloride, Alkaloids, Tannins, Phlobatannins, Steroids, Phenolic compounds, saponins are traced. Antimicrobial activity of the plant extracts were tested by agar well diffusion method against four bacterial pathogens [two Gram positive and two Gram negative strains] such as E. coli, K. pneumoniae, B. cereus and Staphylococcus aureus. In this assay, the leaf and seed of Piper betle extracts showed inhibition activities on Gram negative bacterium such as E. coli and K. pneumoniae. The aqueous extract showed inhibitory activity only on Gram negative bacterium B. cereus and S. aureus. . This present study the qualitative phytochemical analysis and antibacterial activity were analysed.

Medicinal plants are being used since ancient time without knowing about its active ingredients. The healing power of certain plant was understood and accepted before mankind discovered the existence of microorganisms. Herbal drugs constitute a major part in all traditional systems of medicines and are a triumph of popular therapeutic diversity. In India, thousands of plant species are known to have medicinal properties and the use of different parts of several medicinal plants to cure specific ailments have been in vogue since ancient time. In this Present Study the bioactive compounds from the plant Piper betle L. were determined by using HPLC Analysis.