Viet Duc Hospital (aka. Viet Duc University Hospital, Vietnamese: Bệnh viện Việt Đức, literally "Vietnam – Germany Hospital") is the largest surgical center of Vietnam, situated at Trang Thi Street, Hanoi.The Hospital was founded in 1904 as a part of Indochina Medical College by the French colonial governor Paul Doumer.During its history it bore many names: Yersin Hospital (1943), Hospital of Vietnam – GDR (German Democratic Republic) Friendship (1958–1991), Viet Duc Hospital (from 1991 now on).The well known Vietnamese surgeon Ton That Tung more than 40 years conducted his research and operations here.At present, the Hospital has more than 500 beds for patients and 18 surgery rooms and able to perform over 800 open-heart operations annually. It has good cooperation in exchange and training programs with medical facilities in France, Germany, Australia and some other countries. In 1998, the Medicinal Laser Unit was established here to study and apply laser techniques in diagnosis and treatment of some diseases including cancer.In 2006, Hans Messer Foundation in a partnership with East Meets West Foundation and Dräger donated new equipment of total value more than US$160,000 to increase the capacity for children's surgery in the Hospital.The hospital has been a site of collaboration with Facing the World, a UK charity that trains Vietnamese surgeons in craniofacial surgery, sends UK doctors to Vietnam to perform surgeries, and provides equipment to Vietnamese hospitals.
Background:Central venous pressure (CVP)-guided fluid therapy remains common during kidney transplantation, although CVP is a static marker with limited ability to predict fluid responsiveness. This prospective observational cohort study evaluated whether pulse index continuous cardiac output-guided goal-directed hemodynamic therapy (GDHT), using dynamic and volumetric hemodynamic variables, was associated with improved early graft function compared with conventional CVP-guided management in living donor kidney transplantation. Methods:Eighty living donor kidney transplant recipients at Cho Ray Hospital, Vietnam, were enrolled between May 2024 and December 2025. Patients were managed according to the institutional anesthetic monitoring protocol in use at the time of surgery: CVP-guided fluid therapy (group C, n = 40) or PiCCO-guided GDHT (group P, n = 40). The PiCCO protocol incorporated stroke volume variation, pulse pressure variation, cardiac index, global end-diastolic volume index, systemic vascular resistance index, and extravascular lung water index. Outcomes included intraoperative fluid volume, vasopressor use, postoperative urine output, serum creatinine through postoperative day 7, delayed graft function, and postoperative complications. Results:Baseline recipient, donor, and operative characteristics were comparable between groups, with the exception of cold ischemia time, which was longer in group P. Total intraoperative fluid volume was lower in group P than in group C (2,656 ± 480 mL vs. 3,097 ± 555 mL; P = 0.001), and vasopressor use was numerically lower but not statistically significant (12.5% vs. 27.5%; Fisher's exact P = 0.161). First-hour postoperative urine output was higher in group P (1,235 ± 162 mL vs. 1,010 ± 315 mL; P < 0.001). Serum creatinine was similar on postoperative day 1 but was significantly lower in group P on day 3 (1.3 (0.8-1.8) mg/dL vs. 1.6 (1.4-1.9) mg/dL; P = 0.036); the difference on day 7 was not statistically significant (1.1 (0.7-1.4) mg/dL vs. 1.3 (1.1-2.1) mg/dL; P = 0.16). No patient in either group developed delayed graft function within 7 days. Extravascular lung water index remained within the reference range during surgery, and no patient developed clinical pulmonary edema. Conclusions:In this prospective cohort, PiCCO-guided GDHT was associated with lower intraoperative fluid administration, numerically lower vasopressor use, and faster early recovery of graft function after living donor kidney transplantation. These findings support further evaluation of multiparameter hemodynamic monitoring as an individualized perioperative strategy in kidney transplantation.
Objectives:This study evaluates the utility of interim 18F-FDG PET/CT (iPET)-guided therapy in a Southeast Asian population, addressing gaps in region-specific data. Key outcomes included treatment response rates and progression-free survival (PFS) stratified by iPET results (Deauville score (DS) 1-3 vs. 4-5) across all clinical risk groups (including early-stage favorable/unfavorable and advanced-stage based on the International Prognostic Score (IPS)). Findings will inform optimal risk-adapted strategies in resource-aware settings. Methods:A prospective study was conducted of 100 patients with Hodgkin Lymphoma (HL) at the Vietnam National Cancer Hospital from March 2020 to March 2024. All patients underwent baseline clinical assessment and imaging (CT and/or PET/CT), followed by two cycles of ABVD chemotherapy. IPET was performed for early response assessment using Deauville scores (DS), with subsequent treatment adjusted according to NCCN guidelines. Results:A total of 100 patients with classical Hodgkin lymphoma (mean age: 32±13.8 years; range 9-73) were analyzed. Bulky disease and extranodal involvement were observed in 10.0% and 15.0% of cases, respectively. Early-stage disease (stage I-II) was present in 72.0%, and advanced-stage (stage III-IV) in 28.0%. After two cycles of ABVD, 78.0% of patients had a negative iPET result (DS 1-3), of whom 88.5% were DS 1, while 22.0% had a positive iPET result (DS 4-5), predominantly DS 4 (72.7%). In early-stage disease, the 3-year progression-free survival (PFS) was significantly higher in the favorable group than in the unfavorable group (95.7% vs. 81.2%, p=0.03). In advanced-stage disease, low-risk (IPS 0-3) patients achieved a 3-year PFS of 88.2%, whereas high-risk (IPS 4-7) patients had a markedly lower PFS of 42.9% (p<0.001). Overall, patients with negative iPET had substantially better 3-year PFS than those with positive iPET (93.6% vs. 40.9%, p<0.0001). The predictive performance of iPET for treatment outcomes showed a sensitivity of 72.3%, specificity 89.0%, PPV 59.0%, NPV 93.6%, and overall accuracy 86.0% (95% CI 0.78-0.91). Diagnostic accuracy remained high across subgroups, ranging from 84.0% in early-stage disease to 89.5% in advanced-stage, and was highest in favorable early-stage (90.8%) and low-risk advanced-stage (93.7%) patients. In multivariate analysis, iPET was identified as an independent predictor of PFS (p<0.05). Conclusion:In a real-world Vietnamese cohort with Hodgkin lymphoma, interim PET/CT guided by Deauville scoring after two cycles of ABVD chemotherapy showed strong predictive value for treatment response. The results advocate for broader integration of NCCN-consistent risk-adapted strategies in Southeast Asia.
Mục tiêu: Đánh giá kết quả phẫu thuật dẫn lưu não thất – ổ bụng (VPS) và một số yếu tố liên quan ở người bệnh (NB) não úng thủy do lao tại Bệnh viện Phổi Trung Ương giai đoạn 2021–2025. Đối tượng và phương pháp: Nghiên cứu mô tả hồi cứu trên 45 NB não úng thủy do lao được phẫu thuật VPS. Kết quả điều trị được đánh giá dựa trên cải thiện lâm sàng, hình ảnh học và thang điểm Glasgow Outcome Scale (GOS) sau mổ 1 tháng và 6 tháng. Kết quả: Tuổi trung bình là 38,4 ± 18,1; nam giới chiếm 60,0%. Đa số NB ở giai đoạn nặng, với Vellore III–IV chiếm 84,4% và BMRC II–III chiếm 86,7%. Não úng thủy thể thông gặp ở 97,8% trường hợp. Sau phẫu thuật 1 tháng, tỷ lệ kết quả tốt (GOS 4–5) đạt 68,9%; sau 6 tháng là 62,2%. Tỷ lệ tử vong tích lũy sau 6 tháng là 33,3%. Biến chứng chủ yếu là tắc dẫn lưu (13,3%) và nhiễm trùng dẫn lưu (2,2%). Các yếu tố liên quan đến kết cục xấu gồm tuổi ≥ 60, Glasgow thấp, Vellore IV, BMRC III, hạ natri máu, tăng ADA dịch não tủy và nhồi máu não. Kết luận: Phẫu thuật VPS giúp cải thiện triệu chứng tăng áp lực nội sọ và giãn não thất ở NB não úng thủy do lao. Tuy nhiên, tiên lượng còn phụ thuộc vào mức độ nặng lâm sàng và tổn thương nhu mô não trước phẫu thuật.
Autologous bone is a commonly used material for cranioplasty following decompressive craniectomy; however, it is accompanied by the inherent risk of resorption. This study aimed to identify factors associated with bone flap resorption (BFR) in patients undergoing autologous cranioplasty after decompressive craniectomy for traumatic brain injury. A matched case–control study was conducted at Viet Duc University Hospital between January 2022 and July 2025. Cases were defined as patients who developed severe BFR requiring revision surgery. Each case was matched with two controls without BFR based on cranioplasty date and follow-up duration. The association of demographic, general health, trauma history and peri-cranioplasty characteristics with BFR was assessed using conditional logistic regression. A total of 71 cases and 142 matched controls were included in this study. BFR that required surgical revision occurred predominantly within two years after cranioplasty (90
This prospective single-group interventional study aimed to evaluate motor functional recovery and identify factors associated with rehabilitation outcomes in patients following parasagittal meningioma surgery. Thirty patients presenting with postoperative motor weakness after tumor resection participated in a standardized 2-week inpatient rehabilitation program combining physical and occupational therapy, followed by outpatient continuation. Motor and functional outcomes were assessed using the Motor Assessment Scale (MAS), Manual Muscle Testing (MMT), and Functional Independence Measure (FIM) at baseline, 1 month, and 3 months post-intervention. Significant improvements were observed across all scales, with MAS increasing from 30.1 ± 10.9 to 37.8 ± 8.5 and 39.2 ± 8.4, MMT from 126.3 ± 19.8 to 136.0 ± 20.2 and 141.6 ± 18.8, and FIM from 85.0 ± 29.6 to 93.4 ± 20.3 and 99.7 ± 18.6 (p < 0.05 for all comparisons). Generalized Estimating Equations analysis revealed that age, peritumoral edema and preoperative motor weakness were not significant predictors. These findings support the role of early, targeted rehabilitation as a beneficial component of postoperative care for patients with parasagittal meningioma. Larger controlled studies with longer follow-up are required to better delineate recovery trajectories and clarify factors influencing rehabilitation outcomes in this population.
