Tamoxifen, the first targeted anticancer agent for breast cancer, reduces recurrence and mortality. However, nonadherence remains a significant barrier. We investigated the quality, readability, distractibility, and tone of online information regarding tamoxifen. We identified the top four search terms from 2020 to 2025 for tamoxifen using Google Trends. These terms were queried by two independent researchers, and re-queried 2 weeks later to maximize cross-sectional accuracy. Final websites were categorized by authorship. Quality was assessed using the DISCERN instrument and JAMA benchmark criteria. Readability was scored using the Flesch Reading Ease, Flesch-Kincaid Grade Level, Coleman-Liau Index, and SMOG index formula. Distractibility was measured using a validated tool created by Truumees et al. Tone was measured with IBM Watson Natural Language Understanding. Fifty-five unique websites were included. Journal repositories scored significantly higher in quality compared to social media websites (p < 0.05), which had the lowest quality of information. The average text complexity ranged at or above the twelfth grade reading level. Higher quality positively correlated with higher reading level (p < 0.05). There was no difference in the distractibility index or tones across website categories. Online information regarding tamoxifen is overall negative, varies in quality, and may be difficult to understand. Higher quality websites are most difficult for patients to understand, which is detrimental to informed decision-making. Implications for Cancer Survivors Cancer Survivors increasingly access online information. This study provides insight into the websites encountered when searching for tamoxifen online. Clinicians can utilize this information to guide conversations. Cancer Survivors increasingly access online information. This study provides insight into the websites encountered when searching for tamoxifen online. Clinicians can utilize this information to guide conversations.
Older cancer survivors face multidimensional challenges to healthy ageing and independence. Acupuncture has growing evidence for pain and symptom management, but its role in promoting healthy ageing remains unclear. This scoping review mapped evidence across four healthy-ageing-relevant domains, including physical function, psychological distress, cognition, and medication use, and identified knowledge gaps. We searched PubMed, Embase, and Scopus from inception through June 30, 2026. Eligible studies evaluated acupuncture among adult cancer survivors; studies restricted to younger populations were excluded. Findings were extracted and narratively synthesized across the four domains. Of 986 records identified, 39 articles representing 37 studies were included. Most were randomized controlled trials (n = 21, 56.8
Tamoxifen is a key component of adjuvant therapy for hormone receptor–positive breast cancer, but side effects can impair quality of life and adherence. As patients increasingly seek experiential information online, Reddit has become a common platform for discussing tamoxifen. This study seeks to systematically examine its content. Posts and comments referencing “tamoxifen” were extracted from r/breastcancer from 2021 to 2025. Text was de-identified, thematically coded, and analyzed using Bing sentiment scoring and NRC emotion categorization. We analyzed 194 posts and 6013 comments. Side effects were the most frequent theme (45
Cancer imposes substantial physical, psychosocial, and economic burdens on affected individuals, particularly in low- and middle-income countries where out-of-pocket healthcare financing remains dominant. Despite these challenges, evidence on work productivity impairment among patients with cancer in Bangladesh is limited. This study aimed to evaluate work productivity impairment and identify the factors associated with it among cancer patients in Bangladesh. A hospital-based cross-sectional study was conducted among 300 patients with cancer receiving treatment or follow-up care at two tertiary-level hospitals in Bangladesh: Rajshahi Medical College Hospital and Faridpur Medical College Hospital. Work productivity impairment was assessed using the validated Work Productivity and Activity Impairment (WPAI) questionnaire, with overall work impairment derived from absenteeism and presenteeism scores. Descriptive statistics were used to summarize participants’ characteristics and work productivity outcomes, while beta regression analysis was performed to identify factors associated with overall work impairment. The mean absenteeism, presenteeism, and overall work impairment scores were 38.1
Patients with head and neck cancer (HNC) experience substantial symptom burden related to both disease and intensive treatments. Understanding long-term symptom patterns may help identify patients at risk for persistent emotional and physical symptom burden. This study evaluated symptom trajectories of anxiety, depression, fear of cancer recurrence (FCR), and oral pain among patients with HNC from diagnosis through long-term survivorship. This secondary analysis included 5411 patients with HNC from the Head and Neck 5000 study in the UK. Latent class growth analysis (LCGA) and growth mixture modeling (GMM) were used to examine changes in symptoms, predictors of class membership, and within-class variability. The majority of patients were classified into a mild symptom class for depression (58
