New representatives of 1,9-diaza-3,7,11,15-tetraphosphacyclohexadecanes bearing halogen-containing benzyl substituents at the nitrogen atoms have been synthesized via the reaction of 1,3-bis(mesitylphosphino)propane with paraformaldehyde and the corresponding halogen-substituted benzylamines in high yields ranging from 78 to 89
The terephthalaldehyde-based and isophthalaldehyde-based polymers have been synthesized by the reaction of tetrakis(4-aminophenyl)methane with terephthalaldehyde and isophthalaldehyde, respectively, and characterized by IR, XPS, XRD, SEM, TG and BET. SEM reveals that the terephthalaldehyde-based polymer has a higher number of micro-rods than that of the isophthalaldehyde-based polymer, while the number of microspheres is lower, as well as BET indicates that the surface area of the terephthalaldehyde-based polymer is more than twice that of the isophthalaldehyde-based polymer. Methylene blue (MB), rhodamine B (Rh-B) and brilliant blue FCF (BBF) were used as pollutants, and the effects of adsorption dosage, temperature and time on the adsorption properties of polymer particles were studied, respectively. The adsorption experiments show that the max adsorption efficiency of MB, Rh-B and BBF are 81.5
A convenient method for the selective bromination of acetophenone derivatives has been developed using a H2O2–NaBr system in an acidic medium under mild reaction conditions. The reaction carried out at 30–40°C to afford moderate to good yields (up to 80
Magnesium alkoxides NBECH2OMgBr(THF) and NBECH2OMgBr(THF)(TMEDA)0.5 (TMEDA = 1,1,4,4-tetramethylethylenediamine) were synthesized by the reaction of bicyclo[2.2.1]hept-5-en-2-ylmethanol (NBECH2OH) with PhMgBr. It was found that magnesium alkoxide derivatives initiate L-lactide polymerization and lead to the formation of oligomers with a terminal norbornene group. The synthesized oligomers undergo metathesis polymerization and form high-molecular weight polynorbornenes containing oligolactide side groups.
The synthesis and comprehensive study of a new series of unsymmetric (Z)-(2-chloro-2-phenylethenyl)phosphonodiamides, combining styryl, chloro, and phosphorylated fragments in their structure, was presented. The synthesis of the target compounds was accomplished selectively with high yields. The structures of all the compounds obtained have been confirmed by NMR (1H, 13C, 31P), 2D NOESY spectroscopy and high-resolution mass spectrometry. The neurotoxic activity of the synthesized phosphonates was studied using a biosensor system based on butyrylcholinesterase. It has been found that all compounds exhibit weak inhibitory activity in the milli- and centimolar concentration range. The results obtained allow the synthesized styrylphosphonates to be considered as promising objects for further research in medicinal chemistry.
