目的 分析舒适护理联合家庭参与式护理对支气管炎患儿康复效果的影响.方法 选取2021年10月至2022年10月在我院接受治疗的支气管炎患儿70例作为研究对象,将其依照随机数表法进行分组,参照组35例接受舒适护理,观察组35例接受舒适护理联合家庭参与式护理,研究时间为7 d,对两组治疗有效率、各项症状消退时间、患儿的护理依从性以及患儿家长对护理的满意度进行对比.结果 (1)观察组治疗有效率高于参照组(P＜0.05);(2)观察组退热时间、肺啰音消失时间、憋喘症状消失时间、咳嗽症状消失时间均比参照组短(P＜0.05);(3)观察组护理依从性比参照组高(P＜0.05);(4)观察组患儿家长对护理的满意度比参照组高(P＜0.05).结论 对支气管炎患儿实施舒适护理联合家庭参与式护理可显著提升患儿的护理依从性,进而有利于患儿临床症状快速缓解,提高临床疗效.患儿家长对此护理模式的满意度更高,具有较高应用价值.
目的 探究临床护理路径(CNP)模式在肝胆管残余结石患者围术期中的应用效果.方法 选取2018年1月至2021年4月就诊于我院的85例肝胆管残余结石患者,随机分为CNP组(n=43)和常规组(n=42).两组均行胆道镜取石术,常规组接受常规护理干预,CNP组在此基础上联合CNP模式干预.比较两组干预前后疼痛程度、焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分、肝胆管残余结石健康宣教知识掌握度(注意事项、并发症预防方法、肝胆管残余结石知识、饮食知识)、并发症率及护理满意度.结果 干预后CNP组SAS、SDS评分较常规组低(P＜0.05);术后24 h、48 h CNP组疼痛程度较常规组轻(P＜0.05);干预后CNP组注意事项、并发症预防方法、肝胆管残余结石知识及饮食知识评分均较常规组高(P＜0.05);CNP组并发症率2.33％(1/43)较常规组19.05％(8/42)低(P＜0.05);CNP组护理满意度97.67％(42/43)较常规组78.57％(33/42)高(P＜0.05).结论 CNP模式应用于肝胆管残余结石患者围术期可有效改善其心理状态,减轻疼痛感,提升肝胆管残余结石健康宣教知识掌握度,减少并发症发生,提升护理满意度.
目的 探究对糖尿病合并神经外科颅脑损伤患者实施个性化护理对其血糖水平的影响及护理效果.方法 选取我院神经外科2020年1月至2022年12月收治的糖尿病合并颅脑损伤患者80例,以随机信封法进行分组研究,接受常规神经外科护理干预的患者为参照组(n=40),接受个性化护理干预的患者为观察组(n=40),对两组血糖指标、生活自理能力、智力状况以及对护理的满意度进行比较.结果 干预前两组各项血糖指标对比差异无统计学意义(P＞0.05),干预后观察组患者各项血糖指标水平较参照组更低(P＜0.05);干预前两组生活自理能力及智力状况评分对比差异无统计学意义(P＞0.05),干预后观察组两项量表评分均较参照组高(P＜0.05);观察组的护理满意度比参照组高(P＜0.05).结论 对神经外科收治的糖尿病合并颅脑损伤患者实施个性化护理可有效改善患者的血糖水平,并有利于促进患者自理能力以及智力恢复,患者的满意度高,值得推广.
目的 分析疼痛护理质量指标在提高急诊过程中骨科病房疼痛护理质量中的作用.方法 随机选取2021年2月至2023年2月就诊于我院骨科急诊的80例患者作为研究对象,分为对照组与观察组,每组40例.对照组行常规护理,观察组应用疼痛护理质量指标进行护理干预.对比两组护理满意度和疼痛情况.结果 对照组VAS评分高于观察组(P＜0.05);对照组护理质量评分低于观察组(P＜0.05);对照组SDS及SAS评分高于观察组(P＜0.05);对照组生活质量评分低于观察组(P＜0.05).结论 针对骨科急诊患者,疼痛护理质量指标有着良好效果,能够加快患者康复速度并提高生活能力,同时也提高了骨科的服务质量及家属的满意度,值得广泛应用.
目的 探讨基于多学科的整体护理联合积极心理学干预在癫痫患者PET-MRI检查中的应用.方法 将我院78例行PET-MRI检查的癫痫患者随机分为对照组(n=39)和观察组(n=39),对照组给予常规干预,观察组在常规干预基础上实施基于多学科的整体护理联合积极心理学干预,比较两组干预前后的焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分、医学应对方式问卷(MCMQ)评分、候诊时间和检查时间、图像合格率、检查依从性.结果 干预前两组SAS、SDS、MCMQ各量表评分差异无统计学意义(P＞0.05);干预后观察组SAS、SDS、MC-MQ评分优于对照组(P＜0.05);观察组候诊时间、检查时间短于对照组(P＜0.05),检查依从度和图像合格率高于对照组(P＜0.05);观察组不良情况发生率低于对照组(P＜0.05).结论 基于多学科的整体护理联合积极心理学干预有助于缓解行PET-MRI检查的癫痫患者的焦虑抑郁情绪,帮助其建立积极应对方式,提高检查成功率.
目的 研究脑梗死患者抗血小板治疗前后血小板计数(PLT)、血小板平均体积(MPV)及血小板分布宽度(PDW)参数与短期预后的关系.方法 选取2021年1月至2022年12月通许第一医院神经内科一病区、二病区、三病区及脑血管科抗血小板治疗的90例脑梗死患者作为研究对象,3个月后随访,采用改良Rankin量表(mRS)评估预后情况,根据mRS评分情况将患者分为预后良好组(MPS≤2分)和预后不良组(MPS＞2分).比较两组基线资料,抗血小板治疗前后PLT、MPV、PDW等血小板参数变化,并进行多因素Logistic回归分析,采用ROC曲线分析血小板参数与脑梗死患者短期预后的关系.结果 随访结果显示,预后良好组74例,预后不良组16例,两组基线资料中的年龄、性别、吸烟史、饮酒史、基础疾病类型比较,差异无统计学意义(P＞0.05);预后不良组治疗后MPV、PDW水平及治疗前后MPV/PLT水平高于预后良好组,差异有统计学意义(P＜0.05);多因素Logis-tics 回归分析显示,治疗后的MPV水平升高(OR=1.969,95％CI:1.355～2.863)和MPV/PLT水平升高(OR=2.638 × 107,95％C/:5.867 × 103～1.187 × 1011)是脑梗死预后不良的危险因素;ROC曲线分析显示,MPV的ROC曲线下面积为 0.812(95％CI:0.716～0.887),敏感性75.00％,特异性77.03％;MPV/PLT 的 ROC 曲线下面积为 0.908(95％CI:0.828～0.959),敏感性75.00％,特异性93.24％.结论 抗血小板治疗后MPV和MPV/PLT水平升高是脑梗死预后不良的危险因素,并且具有判断脑梗死患者短期预后的价值.
目的 分析快速康复外科(fast track surgery,FTS)理念在膀胱癌(bladder cancer,BC)患者根治性全膀胱切除术围术期护理中的应用效果.方法 回顾性收集我院147例BC患者,均接受根治性全膀胱切除术治疗,将2017年1月至2018年10月在围术期接受常规护理干预的73例作为对照组,将2020年10月至2021年10月在围术期接受FTS理念干预的74例作为观察组,比较两组围术期情况、不同时间点(术前1d及术后1 h、1 d)疼痛程度、并发症指标.结果 观察组术后首次下床活动时间、术后首次排气时间以及住院时间均短于对照组(P＜0.05);两组视觉模拟疼痛评分(visual analogue scale,VAS)比较,差异具有统计学意义(P＜0.05);观察组和对照组不同时间点的VAS评分比较,差异具有统计学意义(P＜0.05);两组VAS评分在时间和组间存在交互作用(P＜0.05);两组术后并发症率比较,观察组为31.08％(23/74),对照组为41.10％(30/73),组间比较差异无统计学意义(P＞0.05).结论 FTS理念护理应用于BC患者根治性全膀胱切除术围术期,能减轻疼痛程度,缩短术后首次下床活动、术后首次排气时间,促进术后恢复.
With the intensification of population aging,diseases in adolescents and elderly people have gradually attracted attention.In these two special age groups,drug treatment needs are very different,so drug research for adolescents and elderly people is particularly important.Sertraline hydrochloride tablet is a multi-indication drug with good efficacy in many diseases,such as anti-depression,anti-anxiety and so on.As a widely used drug,its efficacy has been proven in several fields.With the deepening of clinical research,its application in adolescents and elderly people has been paid more and more attention.In the treatment of diseases in these two age groups,how to rationally use Sertraline hydrochloride tablets and how to avoid potential risks are the focus of this paper.This article will discuss the application of sertraline hydrochloride tablets in these two special age groups,in order to provide more references for clinicians on the application of this drug in different age groups.
目的 对某中学学生常见病进行监测,对监测结果进行分析并提出相应的预防策略.方法 选取2022年3月至12月在某中学就读的中学生2 280人作为本次研究对象,组织学生进行体格检测,主要包括身高、体质量、视力情况、牙齿健康情况、肥胖及营养不良情况,并根据检查结果提出具有针对性的预防策略.结果 (1)2 280名中学生中检出视力不良者1 557名,占比达68.29％;检出龋齿者1 551名,占比达68.03％;检出肥胖者271名,占比达11.89％;检出营养不良者203名,占比达8.90％.按性别比较,女生视力不良占比、龋齿占比均高于男生,肥胖及营养不良占比均低于男生(P＜0.05);按照年级比较,各年级学生视力不良率(七年级47.84％、八年级75.79％、九年级88.98％)对比差异有统计学意义(P＜0.05);各年级学生肥胖率(七年级14.29％、八年级11.84、九年级8.43％)对比差异有统计学意义(P＜0.05);各年级学生营养不良率(七年级10.96％、八年级7.89％、九年级7.13％)对比差异有统计学意义(P＜0.05);各年级学生龋齿率(七年级66.11％、八年级69.74％、九年级69.69％)对比差异无统计学意义(P＞0.05).结论 视力不良、龋齿和肥胖是某中学学生最为多发的疾病,需要重视对学生的正面引导以提高学生主动防病的意识.
目的 为提高妇幼保健工作质量提供理论指导.方法 以2011年至2019年《中国卫生和计划生育统计年鉴》中妇幼保健相关指标为原始资料,运用描述性统计分析方法对数据进行分析,再用TOPSIS法和RSR法对内蒙古自治区妇幼保健相关指标进行分析,并对2010年至2018年妇幼保健服务质量进行评价.结果 2010年至2018年内蒙古自治区妇幼保健服务水平逐年上升,妇幼保健指标总体发展趋向良好.女性常见病检查率保持平稳态势,婚前检查率明显提升;孕产妇死亡率保持连续下降趋势,由33.25/10万下降至12.75/10万,建卡率及住院分娩率连续九年保持高水平态势;新生儿死亡率、婴儿死亡率及5岁以下儿童中重度营养不良比重均呈现下降趋势,分别由10.2‰、12.3‰和0.98％下降至2.8‰、3.8‰和0.6％,7岁以下儿童保健管理率呈上升趋势;2010年的Ci值(相对接近距离)为0.113 7,2018年的Ci值0.900 1,显示内蒙古自治区2010至2018年妇幼保健工作质量有所提升.结论 2010至2018年内蒙古自治区妇幼保健服务质量明显提升,新阶段自治区在保持上升趋势的同时,有针对性地加强薄弱环节,提升综合服务质量.
Objective To summarize and analyze the efficacy and prognosis of rectal cancer patients who did not undergo surgery after chemoradiotherapy for various reasons.Methods A retrospective analysis of 52 patients with rectal cancer who did not undergo surgery after chemoradiotherapy in our department from February 2012 to October 2021.Clinical remission and inci-dence of adverse reactions were analyzed.Kaplan-Meier method was used to calculate the overall survival(OS),and univariate analysis was used to analyze the risk factors for survival.Results After treatment,the local remission rate was 82.6％,CR rate was 5.7％,PR rate 76.9％,SD rate 13.5％and PD rate 3.8％;The 1-yearOSwas59.3％.The 1-year OS of 11 metastatic rec-tal cancer patients was 36.4％.The 1-year OS of 41 locally advanced rectal cancer patients was 65.5％.Most of the ad-verse reactions during treatment are grade 1 or 2,which could be alleviated after symptomatic and supportive treatment.Univariate analysis showed that M stage was significantly associated with 1-year OS.Conclusions For rectal cancer patients without surgery after chemoradiotherapy,the local remission rate of patients after chemoradiotherapy is high,and the adverse reactions are tolerable.Patients with cCR may benefit from watch and wait Strategy.M1 stage at initial diagnosis is significantly associated with poor survival outcomes.
目的 探讨重组人脑利钠肽(rhBNP)辅助治疗急性失代偿性心力衰竭(ADHF)的效果.方法 将2019年1月至2021年1月于我院就诊的103例ADHF患者按照随机数表法分为对照组(n=52)和观察组(n=51).对照组采用单硝酸异山梨酯(ISMN)治疗,观察组采用rhBNP治疗.评估两组疗效、总液体出入量、利尿剂用量、心功能、心肌酶水平、不良反应.结果 观察组总有效率94.12％(48/51)高于对照组80.77％(42/52)(P＜0.05);两组总液体输入量、总液体输出量、液体出入量差值比较,差异无统计学意义(P＞0.05);观察组利尿剂用量低于对照组(P＜0.05);与治疗前相比,治疗后两组LVEF、SV升高,且观察组高于对照组(P＜0.05);治疗后两组LVEDD水平降低,且观察组低于对照组(P＜0.05);观察组的CK、LDH、cTnT均低于对照组(P＜0.05).两组不良反应率比较无统计学意义(P＞0.05).结论 rhBNP辅助治疗ADHF疗效显著,可减少利尿药物的使用剂量,并降低心肌损伤,改善心功能,且安全性与ISMN相同,不增加不良反应.
目的 观察临床上认知康复训练配合高频重复经颅磁刺激对脑卒中后认知障碍伴吞咽障碍的疗效.方法 选取本院2020年1月至2022年12月收治的的脑卒中后认知障碍伴吞咽障碍患者70例,按随机数表法分为试验组35例、对照组35例.试验组实施认知康复训练配合高频重复经颅磁刺激治疗,对照组实施常规治疗.结果 试验组治疗总有效率高于对照组(P＜0.05),试验组吞咽功能测量值低于对照组(P＜0.05),试验组生活能力测量值高于对照组(P＜0.05),试验组生活质量测量值高于对照组(P＜0.05).结论 认知康复训练配合高频重复经颅磁刺激治疗干预措施医治效果更好.
Objective We conducted a meta-analysis to clarify the association between STK39 and hypertension.Meth-ods Published literatures from PubMed,EMBASE,Web of science,and the Cochrane Library were retrieved,and combined odds ratios(OR)of 95％confidence intervals(CI)were calculated using fixed or random effects models.Results Using appropriate inclusion/exclusion criteria,we identified twelve studies that included 24,267 patients with hypertension and 15,935 controls from various ethnic groups.Meta-analysis showed no correlation between STK39 rs3754777 rs35929607 rs6749447 and hyper-tension.The corresponding OR values,95％CI and p values were:[1.15,(0.91,1.46),0.23],[0.95,(0.85,1.06),0.37],[1.18,(0.87,1.61),0.30].In subgroup analysis of populations by race,experimental design,sample size,and year of publication,we showed that studies involving white populations(OR=1.37,95％CI=1.16,1.62,P＜0.05)and prospective design stud-ies(OR=1.36,95％CI=1.01,1.83,P＜0.05),sample size ≥1500(OR=1.44,95％CI=1.01,2.06,P＜0.05),and publica-tion year prior to 2014(excluding 2014)(OR=1.1 1,95％CI=1.02,1.22,P＜0.05)were statistically significant.These studies indicate that site rs3754777 is associated with hypertension.We further confirmed the results through sensitivi-ty analysis.No publication bias was detected.Conclusions The present meta-analysis confirmed no significant associ-ation between STK39 and hypertension,and it is not recommended to study the pathogenesis of SPAK kinase as a pre-ventive measure for hypertension.
Objective To explore the key points of pharmaceutical care for patients with thrombocytopenia after tumor chemotherapy,and to provide reference for clinical pharmacists to participate in the clinical treatment of such patients.Methods Clinical pharmacists participated in the anticoagulation process of a patient with thrombocytopenia complicated with venous thrombosis after chemotherapy,and assisted doctors in optimizing individual treatment plan from the selection of anticoagulants and dosage adjustment.Results Agatraban was selected instead of anticoagulant therapy,and the patient's platelets gradually re-covered and discharged smoothly.Conclusion Clinical pharmacists can improve the effect of anticoagulant therapy and medica-tion safety of patients with tumor-related venous thrombosis by providing individualized medication services.
Objective Based on literature search,meta analysis was conducted on the data of the correlation between aller-gic rhinitis and traditional Chinese medicine constitution,in order to provide effective evidence-based medical basis for the pre-vention and treatment of allergic rhinitis in clinical practice.Methods Literatures were screened through PubMed,CNKI and other databases.AHRQ cross-sectional study quality assessment scale,Stata 12.0 were used for meta-analysis,and then hetero-geneity analysis was performed.Results(1)A total of 266 articles were retrieved,and 11 articles were included in the final analy-sis,with 3848 samples from allergic rhinitis patients.(2)According to the results of meta-analysis,the constitution of allergic pa-tients consisted of Qi-deficiency quality[95％CI=0.35(0.23,0.48),P＜0.01],Yang-deficiency quality[95％CI=0.25(0.17,0.32),P＜0.01],inherited specialties quality[95％CI=0.24(0.14,0.35),P＜0.01],among which Qi-deficiency was the most com-mon.Conclusions Existing evidence shows that Qi-deficiency,Yang-deficiency and inherited specialties deficiency are the main TCM constitution types of patients with allergic rhinitis,and qi-deficiency,Yang-deficiency and genetic specific constitu-tion may be the risk factors for allergic rhinitis.However,this conclusion needs more high-quality,multi-center,large-sample RCT experiments to confirm.
目的 分析CT增强扫描碘造影剂不良反应的预防及护理措施.方法 选取2022年3月至2023年3月我院CT增强扫描患者90例,随机分为对照组和观察组,各45例.对照组实施常规护理,观察组实施加强不良反应的预防与护理,比较两组的干预效果.结果 观察组的不良反应发生率低于对照组(P＜0.05);观察组的护理满意度高于对照组(P＜0.05).结论 进行CT增强扫描时,加强对碘造影剂不良反应的预防及护理,能够降低不良反应发生率,患者满意度高.
目的 针对神经内科睡眠障碍患者行优质护理干预,总结其对患者血压及睡眠质量的影响.方法 选取我院神经内科2021年1月至2021年12月收治的睡眠障碍病例,共计60例,依据随机数表法分为观察组(常规护理+优质护理干预)与对照组(常规护理)各30例.对比两组护理前后血压水平、睡眠质量,问卷调查患者护理满意度.结果 两组舒张压、收缩压护理前差异无统计学意义(P＞0.05),护理后观察组低于对照组,差异具有统计学意义(P＜0.05);两组各项睡眠质量评分护理前比较差异无统计学意义(P＞0.05),护理后均降低,组间比较观察组降低更明显,差异具有统计学意义(P＜0.05);与对照组比较,观察组中表示十分满意、基本满意的患者例数更多,差异具有统计学意义(P＜0.05).结论 神经内科睡眠障碍患者应用优质护理干预,在改善患者血压指标、提升睡眠质量方面效果突出,患者满意度高,可予以推广.
目的 探究硼替佐米联合地塞米松和来那度胺治疗多发性骨髓瘤的临床效果及应用价值.方法 选取2019年1月至2022年6月甘肃医学院附属医院血液内科收治的70例确诊为多发性骨髓瘤患者为研究对象,按照随机数表法分为对照组和观察组,各35例.对照组的治疗方式为BTD方案(硼替佐米+盐酸吡柔比星+地塞米松),观察组治疗方式为VRD方案(硼替佐米+地塞米松+来那度胺).对比两组治疗后疗效和不良反应等指标.结果 观察组的治疗后效果显著高于对照组(P＜0.05);观察组血液指标情况与对照组比较,差异有统计学意义(P＜0.05);观察组在周围神经炎发生方面显著少于对照组(P＜0.05),而在其他不良反应方面与对照组比较,差异无统计学意义(P＞0.05).结论 硼替佐米联合地塞米松和来那度胺对多发性骨髓瘤的治疗效果理想,其耐受性好,疗效更高,且不良反应相对少,更能保障患者用药安全,其临床应用价值大,值得广泛推广.
Dyslipidemia is an important risk factor for cardiovascular and cerebrovascular diseases and metabolic diseas-es.The prevalence of dyslipidemia in Chinese population has been increasing year by year,which has become a major social and public health problem.Sleep is an indispensable part of human life and an important regulatory factor of lipid metabolism.Studies have shown that chronic sleep deprivation can cause dyslipidemia by affecting fatty acid metabolism.This paper aims to review the correlation between sleep deprivation and dyslipidemia,and explore the pathophysiological mechanism of fatty acid induced dyslipidemia in people with sleep deprivation,so as to provide theoretical guidance and scientific basis for the prevention and im-provement of dyslipidemia caused by insufficient sleep duration.
