To date, more than 300 compounds have been isolated and identified from Dihuang (Rehmanniae Radix). Analysis of the chemical composition distribution reveals significant differences among different processed products and plant parts. Xiandihuang (Radix Rehmanniae Recens) contains a greater variety of compounds, and the processing methods significantly impact the types and quantities of compounds, with most components decreasing as processing intensifies. Furthermore, although the leaves and root tubers of Dihuang (Rehmanniae Radix) share consistency in chemical constituent types—including iridoids, phenylethanoid glycosides, ionones, etc.—there are differences in the specific monomeric compounds and their content. They exhibit unique site specificity in the distribution of certain compound classes, such as nitrogen-containing compounds, sesquiterpenoids, and lignans. Iridoids, phenylethanoid glycosides, and polysaccharides are the primary material basis for the pharmacological efficacy of Dihuang (Rehmanniae Radix), demonstrating activities such as hypoglycemic, antiosteoporotic, antitumor, and anti-inflammatory effects. Future research directions may focus on the following aspects: First, directed breeding and gene editing. Based on superior varieties and leveraging their genetic advantages, key genes regulating the biosynthesis of active components like iridoids, ionones, phenylethanoids, and sesquiterpenoids can be precisely located. Targeted modification via gene editing can then be employed for variety improvement. Concurrently, high-density linkage maps constructed from the genetic differences among varieties can be used to analyze relevant quantitative trait loci, providing molecular genetic evidence for the directed breeding of superior rehmannia varieties. Second, pharmacological optimization research based on compositional specificity. Investigating the mechanism of action in specific diseases and the synergistic effects of multicomponents according to the compositional characteristics of different varieties can provide a basis for clinical “variety selection based on syndrome differentiation.”
Many people engagingin medical scienceasked me,"You’ve beenworking on the exploration of Holistic Integrated Medicine（HIM）for quite awhile.What is the progressyou have made in your research?Have you got your article published?May I beyour first reader?"
Professor Xu Fengqin,based on pictographic thinking and the theory of the Five Elements,believes that the Heart belongs to Fire in the Five Elements,governing the pulse and storing Shen.After percutaneous coronary intervention(PCI),anxiety and depression patients have symptoms of Jun Fire dysfunction and Xiang Fire hyperactivity,blood stasis,Heart pulse injury,and eventually damage the Heart and Shen.The key point of the clinical treatment is to reverse that,by treating from the perspective of Fire.Chaihu,Longgu Muli Decoction and Jieyu Hehuan Decoction,etc.Can be used.With multiple methods the Fire would be located in the right place(De Huo Jiu Fan)so the two Fires perform their respective duties and settle down in their respective positions.Specifically,the Fire in the South will be under the Water in the North and become the harmonious pair.The Heaven and Earth will be restored to the best condition.The Shen will be in harmony with Heart and people will be at peace of mind.
The pathogenic factors of ankylosing spondylitis are no more than the three core pathogenesis of"deficiency,blood stasis,and Qi stagnation",which are manifested as congenital Kidney deficiency and Du meridian deficiency,Spleen and Stomach deficiency,mutu-al accumulation of blood stasis,and Liver Qi stagnation.Skilled medication is used to supplement congenital Kidney Qi,regulate the ac-quired Spleen and Stomach,promote blood circulation and meridian circulation,and ease emotions.The combination of Gouji(rhizoma cibotii)and Duzhong(eucommia ulmoides)can synergistically exert the effects of warming,tonifying,firming,tonifying the Kidney and strengthening Du meridian.It can be used to treat symptoms such as Liver and Kidney deficiency,waist and knee soreness,and lower limb weakness.It can also treat Kidney deficiency and lower back pain.The combination of Danggui(angelica sinensis)and Shoudi-huang(rehmannia glutinosa)can not only benefit the Essence and fill the marrow,regulate menstruation and relieve pain but also en-hance man's vital energy;The combination of Ruxiang(frankincense)and Moyao(myrrh)can promote blood circulation,relieve pain,reduce swelling,and anti-inflammatory effects;Quanxie(scorpion)and Wugong(centipede)combination function in tonifying Qi,re-solving blood stasis,reducing Phlegm,and relieving pain.The combination of Yiyiren(coix seed)and Fuling(poria cocos)nourishes the acquired Essence,with Spleen and Stomach controlling the muscles and limbs,protecting the muscles and bones.The Spleen and Stomach are healthy,nourishing the muscles and bones,thus having a significant therapeutic effect on relieving joint stiffness and pain;Chaihu(radix bupleuri)and Huangqin(scutellaria baicalensis)works from perspective of Liver,nourishing and soothing the Liver,nourishing Liver blood,regulating Liver Qi,and alleviating anxiety and Qi stagnation.
Objective:To analyze the effect of emotional therapy of traditional Chinese medicine on anxiety,depression and ruminant thinking of patients with human immunodeficiency virus(HIV)AIDS.Method:100 HIV/AIDS patients with anxiety and depression symptoms were randomly divided into a control group and an observation group.The control group received conventional medication treatment,while the observation group received traditional Chinese medicine emotional therapy based on the treatment.Both groups of patients underwent continuous intervention for 3 months.Before and after the intervention,patients were evaluated using the Self Rating Anxiety Scale(SAS),Self Rating Depression Scale(SDS),and Ruminative Response Scale(RRS).Result:After intervention,the SAS score of the observation group was(68.450±8.830)points,while the SAS score of the control group was(74.600±9.342)points.The observation group was significantly lower than the control group during the same period(P<0.05).The SDS score of the observa-tion group was(70.525±7.500)points,while the SDS score of the control group was(76.135±7.534)points.The observation group was significantly lower than the control group during the same period(P<0.05).The RRS score of the observation group was(49.290±9.420)points,while the RRS score of the control group was(57.900±11.112)points.The observation group was signifi-cantly lower than the control group during the same period(P<0.05).Conclusion:Traditional Chinese medicine emotional therapy has a certain therapeutic effect on HIV/AIDS patients,which can effectively reduce anxiety and depression symptoms and improve patients'rumination thinking.
