• 学术搜索
  • 科研智能体
    • Research Labs
    • AI 阅读
    • AI 文库
    • 深度研究
    • 学者亮点
  • 学术资源
    • AI2000
    • 期刊/会议
    • 学者库
    • 学术API
      MCP&Skill
    • 溯源树
    • 数据集
  • 知识沉淀
    • 学术空间
订阅小程序
旧版功能
aminer vip
开通会员低至0.73元/天
一次搞定AI科研
立即登录
  • English
  • 联系方式
    Biotechnology (Reading, Mass.)

    Biotechnology (Reading, Mass.)

    JournalISSN 0740-7378

    年发文量

    研究主题

    论文(454)

    排序
    1Biotechnology in the Pulp and Paper Industry
    Liisa Viikari, Mana Tenkanen,Anna Suurnäkki

    This chapter contains sections titled: Introduction Enzymes for the Pulp and Paper Industry Enzymes as Process Aids Enzymes for Product Design Biorefinery Concepts Conclusions References

    2001引用:1
    引用
    AI阅读
    加入学术空间
    2Genomic Data Representation Through Images‐Magpie As an Example
    Paul Gordon,Terry Gaasterland,Christoph W. Sensen

    This chapter contains sections titled: Introduction The Graphical System Conclusions and Open Issues References

    2001引用:2
    引用
    AI阅读
    加入学术空间
    3Genomics and Human Disease
    Roger C. Green

    Chapter 4 Genomics and Human Disease Roger C. Green, Roger C. Green St. John's, CanadaSearch for more papers by this author Roger C. Green, Roger C. Green St. John's, CanadaSearch for more papers by this author Book Editor(s):Prof. Dr. H. J. Rehm, Prof. Dr. H. J. Rehm Institut für Mikrobiologie Universität Münster Corrensstraße 3 D-48149 Münster FRGSearch for more papers by this authorDr. G. Reed, Dr. G. Reed 1029 N. Jackson St. #501-A, Milwaukee, WI 53202-3226 USASearch for more papers by this author First published: 25 April 2001 https://doi.org/10.1002/9783527620876.ch4 AboutPDFPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShareShare a linkShare onEmailFacebookTwitterLinkedInRedditWechat Summary This chapter contains sections titled: Introduction Identification of Disease-Associated Genes Diagnostics and Genetic Testing Treatment Conclusions References References Allen. R. L., et al. 1999, The role of HLA-B27 in spondyloarthritis, Immunogenetics 50: 220—227. 10.1007/s002510050596 CASPubMedWeb of Science®Google Scholar Annas. G. J., 2000, Rules for research on human genetic variation-lessons from Iceland, N. Engl. J. Med. 342: 1830—1833. 10.1056/NEJM200006153422412 CASPubMedWeb of Science®Google Scholar Anonymous 1995, Positional Cloning Approach Expedites Gene Hunts, Human Genome News 6: 1. Google Scholar Aparicio, S.A. 2000, How to count human genes. Nature Genet. 25: 129—130. 10.1038/75949 CASPubMedWeb of Science®Google Scholar Botstein. D., 1999. Of genes and genomes, Ann. N.Y. Acad. Sci. 882: 32—41. 10.1111/j.1749-6632.1999.tb08531.x CASPubMedWeb of Science®Google Scholar Bradley, B.A., Evers, B.M. 1997, Molecular advances in the etiology and treatment of colorectal cancer, Surg. Oncol. 6: 143—156. 10.1016/S0960-7404(97)00020-0 CASPubMedWeb of Science®Google Scholar Buckley, R.H. 2000, Gene therapy for human SCID: Dreams become reality, Nature Med. 6: 623—624. 10.1038/76185 CASPubMedWeb of Science®Google Scholar Cambien, E, et al. 1992, Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction, Nature 359: 641—644. 10.1038/359641a0 CASPubMedWeb of Science®Google Scholar Cavazzana-Calvo, M., et al. 2000, Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease, Science 288: 669—672. 10.1126/science.288.5466.669 CASPubMedWeb of Science®Google Scholar Collins. F. S., et al. 1997, Variations on a theme: cataloging human DNA sequence variation, Science 278: 1580—1581. 10.1126/science.278.5343.1580 CASPubMedWeb of Science®Google Scholar Corder, E.H. et al. 1993, Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer’s disease in late onset families, Science 261: 921—923. 10.1126/science.8346443 CASPubMedWeb of Science®Google Scholar Cotton, R.G. H. 1997, Mutation Detection. Oxford: Oxford University Press. Google Scholar De Braekeleer, M. 1991, Hereditary disorders in Saguenay-Lac-St.-Jean (Quebec, Canada), Hum. Hered. 41: 141—146. 10.1159/000153992 CASPubMedWeb of Science®Google Scholar De La Chapelle, A. 1993, Disease gene mapping in isolated human populations: the example of Finland. J. Med. Genet. 30: 857—865. 10.1136/jmg.30.10.857 PubMedWeb of Science®Google Scholar De Vos, A., et al. 1998, Pregnancy after preimplantation genetic diagnosis for Charcot-Marie-Tooth disease type 1 A, Mol. Hum. Reprod. 4: 978—984. 10.1093/molehr/4.10.978 CASPubMedWeb of Science®Google Scholar Enlund, F., et al. 1999, Psoriasis susceptibility locus in chromosome region 3q21 identified in patients from southwest Sweden, Eur. J. Hum. Genet. 7: 783—790. 10.1038/sj.ejhg.5200365 CASPubMedWeb of Science®Google Scholar Evans, W.E., Relling, M.V. 1999, Pharmacogenomics: translating functional genomics into rational therapeutics, Science 286: 487—491. 10.1126/science.286.5439.487 CASPubMedWeb of Science®Google Scholar Ewing, B., Green, P. 2000, Analysis of expressed sequence tags indicates 35,000 human genes, Nature Genet. 25: 232—234. 10.1038/76115 CASPubMedWeb of Science®Google Scholar Grann, V.R. et al. 2000, Prevention with tamoxifen or other hormones versus prophylactic surgery in BRCAl/2-positive women: a decision analysis, Cancer J. Sci. Am. 6: 13—20. CASPubMedWeb of Science®Google Scholar Gusella, J.E., et al. 1983, A polymorphic DNA marker genetically linked to Huntington’s disease, Nature 306: 234—238. 10.1038/306234a0 CASPubMedWeb of Science®Google Scholar Hacia, J. G, 1999, Resequencing and mutational analysis using oligonucleotide microarrays, Nature Genet. 21: 42—47. 10.1038/4469 CASPubMedWeb of Science®Google Scholar Hanis, C.L. et al. 1996, A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2, Nature Genet. 13: 161—166. 10.1038/ng0696-161 CASPubMedWeb of Science®Google Scholar Helgason, A., et al. 2000, mtDNA and the origin of the Icelanders: deciphering signals of recent population history, Am. J. Hum. Genet. 66: 999—1016. 10.1086/302816 CASPubMedWeb of Science®Google Scholar Heyer, E., et al. 1997, Seventeenth-century European origins of hereditary diseases in the Saguenay population (Quebec, Canada), Hum. Biol. 69: 209—225. CASPubMedWeb of Science®Google Scholar Hudson, T.J. et al. 1995, An STS-based map of the human genome, Sience 270: 1945—1954. 10.1126/science.270.5244.1945 CASPubMedWeb of Science®Google Scholar Hurme, M., et al. 1998, Gene polymorphisms of interleukins 1 and 10 in infectious and autoimmune diseases, Ann. Med. 30: 469—473. 10.3109/07853899809002488 CASPubMedWeb of Science®Google Scholar Ikeda M. Yu, D.T. 1998, The pathogenesis of HLA-B27 arthritis: role of HLA-B27 in bacterial defense, Am. J. Med. Sci. 316: 257—263. 10.1097/00000441-199810000-00006 CASPubMedWeb of Science®Google Scholar Ingram, V.M. 1959, Abnormal human haemoglobin. III. The chemical difference between normal and sickle cell haemoglobins, Biochim. Biophys. Acta 36: 402—411. 10.1016/0006-3002(59)90183-0 CASPubMedWeb of Science®Google Scholar Jeunemaitre, X., et al. 1992, Molecular basis of human hypertension: role of angiotensinogen, Cell 71: 169—180. 10.1016/0092-8674(92)90275-H CASPubMedWeb of Science®Google Scholar Kronn, D., et al. 1998, Carrier screening for cystic fibrosis, Gaucher disease, and Tay-Sachs disease in the Ashkenazi Jewish population: the first 1000 cases at New York University Medical Center, New York, NY, Arch. Intern. Med. 158: 777—781. 10.1001/archinte.158.7.777 CASPubMedWeb of Science®Google Scholar Kuliev, A., et al. 1999, Birth of healthy children after preimplantation diagnosis of thalassemias, J. Assist. Reprod. Genet. 16: 207—211. 10.1023/A:1020316924064 CASPubMedWeb of Science®Google Scholar Kurg, A., et al. 2000, Arrayed primer extension: solid-phase four-color DNA resequencing and mutation detection technology, Genet. Test. 4: 1—7. 10.1089/109065700316408 CASPubMedWeb of Science®Google Scholar Lathrop, G.M. et al. 1985, Multilocus linkage analysis in humans: detection of linkage and estimation of recombinations, Am. J. Hum. Genet. 37: 482—498. PubMedWeb of Science®Google Scholar Liang, E, et al. 2000, Gene index analysis of the human genome estimates approximately 120,000 genes, Nature Genet. 25: 239—240. 10.1038/76126 CASPubMedWeb of Science®Google Scholar Lynch, H.T. et al. 1999, Clinical impact of molecular genetic diagnosis, genetic counseling, and management of hereditary cancer: Part II: Hereditary nonpolyposis colorectal carcinoma as a model, Cancer 86: 2457—2463. 10.1002/(SICI)1097-0142(19991201)86:11+<2457::AID-CNCR2>3.0.CO;2-I CASPubMedWeb of Science®Google Scholar Mathew, C.G. 1999, DNA diagnostics: goals and challenges, Br. Med. Bull. 55: 325—339. 10.1258/0007142991902402 CASPubMedWeb of Science®Google Scholar Mckusick, V.A. (Ed.) 1966, Mendelian Inheritance in Man. Baltimore, MD: Johns Hopkins University Press. Google Scholar Nyholt, D.R. et al. 1998a, Familial typical migraine: linkage to chromosome 19pl3 and evidence for genetic heterogeneity, Neurology 50: 1428—1432. 10.1212/WNL.50.5.1428 CASPubMedWeb of Science®Google Scholar Nyholt, D.R. et al. 1998b, Evidence for an X-linked genetic component in familial typical migraine, Hum. Mol. Genet. 7: 459—463. 10.1093/hmg/7.3.459 CASPubMedWeb of Science®Google Scholar Palu, G., et al. 1999, In pursuit of new developments for gene therapy of human diseases, J. Biotechnol. 68: 1—13. 10.1016/S0168-1656(98)00134-5 CASPubMedWeb of Science®Google Scholar Parens, E. 1996, Glad and terrified: On the ethics of BRCA1 and 2 testing, Cancer Invest. 14: 405—411. 10.3109/07357909609012169 CASPubMedWeb of Science®Google Scholar Peltonen, L. 2000, Positional cloning of disease genes: advantages of genetic isolates, Hum. Hered. 50: 66—75. 10.1159/000022892 CASPubMedWeb of Science®Google Scholar Petersen, G.M. et al. 1999, Genetic testing and counseling for hereditary forms of colorectal cancer, Cancer 86: 2540—2550. 10.1002/(SICI)1097-0142(19991201)86:11+<2540::AID-CNCR11>3.0.CO;2-8 CASPubMedWeb of Science®Google Scholar Pile, K.D. 1999, Broadsheet number 51: HLA and disease associations, Pathology 31: 202—212. 10.1080/003130299104972 CASPubMedWeb of Science®Google Scholar Risch, N.J. 2000, Searching for genetic determinants in the new millennium, Nature 405: 847—856. 10.1038/35015718 CASPubMedWeb of Science®Google Scholar Risch N. Merikangas, K. 1996, The future of genetic studies of complex human diseases, Science 273: 1516—1517. 10.1126/science.273.5281.1516 CASPubMedWeb of Science®Google Scholar Roger, M. 1998, Influence of host genes on HIV-1 disease progression, FASEB J. 12, 625—632. 10.1096/fasebj.12.9.625 CASPubMedWeb of Science®Google Scholar Roses, A.D. 1997, A model for susceptibility polymorphisms for complex diseases: apolipoprotein E and Alzheimer disease, Neurogenetics 1: 3—11. 10.1007/s100480050001 CASPubMedWeb of Science®Google Scholar Roses, A.D. 2000, Pharmacogenetics and the practice of medicine, Nature 405: 857—865. 10.1038/35015728 CASPubMedWeb of Science®Google Scholar Ruschoff, J., et al. 1998, Aspirin suppresses the mutator phenotype associated with hereditary nonpolyposis colorectal cancer by genetic selection, Proc. Natl. Acad. Sci. USA 95: 11301—11306. 10.1073/pnas.95.19.11301 CASPubMedWeb of Science®Google Scholar Seamark, C.J., Hutchinson, M. 2000, Controversy in primary care. Should asymptomatic haemochromatosis be treated? Br. Med. J. 320: 1314—1317. 10.1136/bmj.320.7245.1314 CASPubMedWeb of Science®Google Scholar Service, S.K. et al. 1999, Linkage-disequilibrium mapping of disease genes by reconstruction of ancestral haplotypes in founder populations. Am. J. Hum. Genet. 64: 1728—1738. 10.1086/302398 CASPubMedWeb of Science®Google Scholar Shaw, J.T. et al. 1998, Novel susceptibility gene for late-onset NIDDM is localized to human chromosome 12q. Diabetes 47: 1793—1796. 10.2337/diabetes.47.11.1793 CASPubMedWeb of Science®Google Scholar Sheffield, V.C. et al. 1998. Use of isolated inbred human populations for identification of disease genes, Trends Genet. 14: 391—396. 10.1016/S0168-9525(98)01556-X CASPubMedWeb of Science®Google Scholar Smith. A. E., 1999. Gene therapy-where are we? Lancet 354 (Suppl. 1). SI1—SI4. 10.1016/S0140-6736(99)90240-4 PubMedWeb of Science®Google Scholar Syngal. S., et al. 1999, Interpretation of genetic test results for hereditary nonpolyposis colorectal cancer: implications for clinical predisposition testing, JAMA 282: 247—253. 10.1001/jama.282.3.247 CASPubMedWeb of Science®Google Scholar Syvanen. A. C., 1999. From gels to chips: “minisequencing” primer extension for analysis of point mutations and single nucleotide polymorphisms, Hum. Mut. 13. 1—10. 10.1002/(SICI)1098-1004(1999)13:1<1::AID-HUMU1>3.0.CO;2-I CASPubMedWeb of Science®Google Scholar Taillon-Miller, P., et al. 1999, Efficient approach to unique single-nucleotide polymorphism discovery, Genome Res. 9: 499—505. CASPubMedWeb of Science®Google Scholar The Huntington’s Disease Collaborative Research Group 1993, A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington’s disease chromosomes, Cell 72: 971—983. 10.1016/0092-8674(93)90585-E PubMedWeb of Science®Google Scholar Thorsby, E. 1997, Invited anniversary review: HLA associated diseases, Hum. Immunol. 53: 1—11. 10.1016/S0198-8859(97)00024-4 CASPubMedWeb of Science®Google Scholar Tonisson, N., et al. 2000, Unravelling genetic data by arrayed primer extension, Clin. Chem. Lab. Med. 38: 165—170. 10.1515/CCLM.2000.025 CASPubMedWeb of Science®Google Scholar Van Ommen, G.J. et al. 1999, The human genome project and the future of diagnostics, treatment, and prevention, Lancet 354, (Suppl. 1), SI5—10. 10.1016/S0140-6736(99)90241-6 PubMedWeb of Science®Google Scholar Wang. J. H., Hewick, R.M. 1999, Proteomics in drug discovery, Drug Discov. Today 4: 129—133. 10.1016/S1359-6446(99)01306-9 PubMedWeb of Science®Google Scholar Biotechnology: B: Genomics and Bioinformatics, Volume 5, Second Edition ReferencesRelatedInformation

    2001引用:1
    引用
    AI阅读
    加入学术空间
    4Biotechnology in Plant Protection
    Frank Niepold, Klaus Rudolph

    Chapter 16 Biotechnology in Plant Protection Frank Niepold, Frank Niepold Braunschweig, GermanySearch for more papers by this authorKlaus Rudolph, Klaus Rudolph Göttingen, GermanySearch for more papers by this author Frank Niepold, Frank Niepold Braunschweig, GermanySearch for more papers by this authorKlaus Rudolph, Klaus Rudolph Göttingen, GermanySearch for more papers by this author Book Editor(s):Prof. Dr. H.-J. Rehm, Prof. Dr. H.-J. Rehm Institut für Mikrobiologie, Universität, Münster, Corrensstraße 3, D-48149 Münster, FRGSearch for more papers by this authorDr. G. Reed, Dr. G. Reed 1029 N. Jackson St.,#501-A, Milwaukee, WI 53202-3226, USASearch for more papers by this author First published: 05 October 2001 https://doi.org/10.1002/9783527620937.ch16Citations: 2 AboutPDFPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShareShare a linkShare onFacebookTwitterLinked InRedditWechat Summary The prelims comprise: Introduction Biocontrol of Plant Pathogens or Weeds by Living Organisms Plants Transformed with Bacterial, Fungal or Non-Indigenous Genes Reducing Diseases Caused by Fungi or Bacteria Virus Resistant Plants Antibodies Produced in Plants as Plant Protection Products Herbicide Resistant Crops Mechanisms of Plants for Protection against Pathogen Attack by “Systemic Acquired Resistance” Use of Beneficial Arthropods and Sterile Insect Release Insect Pathogenic Microorganisms Pheromones Serology and DNA Procedures as Detection Tools Biotechnologically Produced Plant Protection Products Authorized in Germany Discussion and Outlook Citing Literature Biotechnology: Special Processes, Volume 10, Second Edition RelatedInformation

    2001
    引用
    AI阅读
    加入学术空间
    5Structure Information
    Mirosław Cygler, Allan Matte and,Joseph D. Schrag

    Chapter 15 Structure Information Miroslaw Cygler, Miroslaw Cygler Montreal, CanadaSearch for more papers by this authorAllan Matte, Allan Matte Montreal, CanadaSearch for more papers by this authorJoseph D. Schrag, Joseph D. Schrag Montreal, CanadaSearch for more papers by this author Miroslaw Cygler, Miroslaw Cygler Montreal, CanadaSearch for more papers by this authorAllan Matte, Allan Matte Montreal, CanadaSearch for more papers by this authorJoseph D. Schrag, Joseph D. Schrag Montreal, CanadaSearch for more papers by this author Book Editor(s):Prof. Dr. H. J. Rehm, Prof. Dr. H. J. Rehm Institut für Mikrobiologie Universität Münster Corrensstraße 3 D-48149 Münster FRGSearch for more papers by this authorDr. G. Reed, Dr. G. Reed 1029 N. Jackson St. #501-A, Milwaukee, WI 53202-3226 USASearch for more papers by this author First published: 25 April 2001 https://doi.org/10.1002/9783527620876.ch15 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Summary This chapter contains sections titled: Introduction Protein Fold Evolution and Three-Dimensional Structure Structure to Function, Structural Signatures Homology Modeling Fold Recognition by Threading Virtual Screening Molecular Machines De nevo Protein Design References Biotechnology: B: Genomics and Bioinformatics, Volume 5, Second Edition RelatedInformation

    2001
    引用
    AI阅读
    加入学术空间
    立即登录,查看全部 454 篇论文

    高被引作者

    作者引用发文
    F. Sanger919101
    Harry Towbin680871
    J Gordon680871
    T Staehelin680871
    Ed Southern374991
    César Milstein208871
    G Köhler208871
    Henry A. Erlich148793
    Randall K. Saiki143582
    S Scharf143582

    高产作者

    作者引用发文
    Henry A. Erlich148793
    Max Roehr253
    Raymond L. Rodriguez67513
    Francisco Bolívar80713
    Mark Sopwith73
    Howard M. Goodman23093
    HW BOYER82143
    Josef Winter42
    Ralph Brinster26962
    F Faloona143582

    相关期刊

    Journal of molecular signaling
    Chinese Journal of Cancer Biotherapy
    The Molecular Biology Society of Japan
    Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology
    Chinese bulletin of Life sciences
    Chinese Journal of Biochemistry and Molecular Biology
    Carcinogenesis,Teratogenesis & Mutagenesis
    Biotechnology
    Chinese Journal of Cell Biology
    中华细胞与干细胞杂志(电子版)