Objective To analyse and explore the effect of early skull defect repair after craniocerebral trauma operation on prognosis of the patients.Methods Randomly selected in our hospital early cranioplasty(early group) and late cranioplasty(late group) of the 28 cases,respectively,and recovery and postoperative neurological function were compared between two groups after 2 months when the incidence of adverse reaction.Results The early group 2 months after operation the KPS score(81.69±12.68) points,significantly better than the late group(71.56±14.3) points(P0.05);the early group GOS prognostic evaluation also was better than the late group(P0.05);complications compared with the early group of five cases,the late group of six cases.The two groups showed no significant difference(P0.05).Conclusion The application of post-operative craniocerebral trauma skull defect in the treatment of early cranioplasty is better than late cranioplasty.
Objective:To analyze the curative effects of CT-guided ozone injection combined with radiofrequency thermocoagulation on lumbar disc herniation.Methods:Seventy patients with lumbar disc herniation admitted to Zhumadian Central Hospital from January 2021 to January 2023 were selected and divided into control group and observation group according to random number table method, with 35 cases in each group. The control group received CT-guided radiofrequency thermocoagulation, and the observation group received CT-guided ozone injection combined with radiofrequency thermocoagulation. The excellent and good rate, Japanese Orthopaedic Association (JOA) score, Oswestry disability index (ODI) score, numerical rating scale (NRS) score and incidence of adverse reactions of the two groups were compared.Results:The excellent and good rate of the observation group was 97.14% (34/35), higher than the 71.43% (25/35) of the control group ( P<0.05). After treatment, the JOA score in the observation group was higher than that in the control group, while the ODI score was lower than that in the control group ( P<0.05). After treatment, the NRS score of the observation group was lower than that of the control group ( P<0.05). There was no significant difference in the incidence of adverse reactions between the observation group (2.86%, 1/35) and the control group (17.14%, 6/35), P>0.05. Conclusions:CT-guided ozone injection combined with radiofrequency thermocoagulation, in the treatment of lumbar disc herniation, can improve the excellent and good rate, reduce pain degree and improve lumbar function.
Objective:To observe the effect of transcranial focused ultrasound stimulation combined with cognitive training on the rehabilitation of patients with severe head injury.Methods:This study was s prospective cohort trail. A total of 80 patients with severe head injury who received rehabilitation treatment in the First Affiliated Hospital of Zhengzhou University from January 2021 to December 2022 were selected as the research objects. They were divided into control group and observation group by random number table method, with 40 cases in each group. The control group received cognitive training, while the observation group received transcranial focused ultrasound stimulation based on the intervention of the control group. The serum indicator brain-derived neurotrophic factor (BDNF), neurological function assessed by National Institute of Health stroke scale (NIHSS) and modified Rankin scale (mRS), cognitive function assessed by Montreal cognitive assessment (MoCA) score, and self-care ability assessed by activity of daily living scale (ADL) score were compared between the two groups before and after treatment.Results:After treatment, the BDNF level, MoCA score, and ADL score in the two groups were higher than those before treatment, and the above indicators in the observation group were higher than those in the control group ( P<0.05). After treatment, the NIHSS score and mRS score of the two groups were lower than those before treatment, and the observation group had lower scores of NIHSS and mRS than the control group ( P<0.05). Conclusions:The combination of transcranial focused ultrasound stimulation and cognitive training can effectively improve neurological and cognitive function, and enhance self-care ability in patients with severe head injury.
Objective:To compare the clinical effect of closed reduction interlocking intramedullary fixation and internal fixation with plates and screw in the treatment of traumatic fractures of long tubular bone in the limbs.Methods:A total of 70 patients with traumatic fracture of long tubular bone in th limbs admitted to Puyang People’s Hospital from January 2021 to January 2023 were selected, and all the patients were divided into control group and observation group by random number table method, with 35 cases in each group. The control group was treated by closed reduction interlocking intramedullary fixation. The observation group was treated by internal fixation with plates and screw. The excellent and good rate of fracture healing, surgical indicators, incidence of complications, and degree of pain were compared between the two groups.Results:The excellent and good rate of fracture healing in the observation group (94.29%, 33/35) was higher than that in the control group (77.14%, 27/35), P<0.05. The intraoperative bleeding in the observation group was less than that in the control group, moreover, the fracture healing time, surgical time, and hospital stay were all shorter than those in the control group ( P<0.05). The incidence of complications in the observation group (2.86%, 1/35) was lower than that in the control group (20.00%, 7/35), P<0.05. After treatment, the visual analogue scale score of the two groups decreased, compared with preoperative scores ( P<0.05); and the observation group had lower visual analogue scale score than the control group after treatment ( P<0.05). Conclusions:The internal fixation with plates and screw has a good effect in the treatment of patients with traumatic fractures of long tubular bone in the limbs, which can effectively promote patient recovery, reduce complications, and alleviate pain.
Objective:To investigate the effect of nifedipine combined with labetalol on gestational hypertension and its influence on serum alkaline phosphatase (ALP) level, leucine aminopeptidase (LAP) level, and blood coagulation function.Methods:A total of 104 patients with gestational hypertension admitted to the First People’s Hospital of Zhumadian from March 2021 to April 2022 were selected, and they were divided into control group and observation group by random number table method, with 52 cases in each group. The control group was treated with labetalol, and the observation group was treated with nifedipine combined with labetalol. Both groups were treated for 10 days continuously. The clinical efficacy, levels of serum ALP and LAP, blood pressure level, coagulation function, which was assessed by thrombin time (TT), prothrombin time (PT), activeated partial thromboplasting time (APTT) and fibrinogen (FIB), pregnancy outcomes, and incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group (94.23%, 49/52) was higher than that of the control group (78.85%, 41/52), with a statistically significant difference ( P<0.05). After treatment, the levels of serum LAP and ALP in the observation group were (12.86±3.02) U/L and (265.69±50.26) U/L, respectively, which were higher than the (11.53±2.81) U/L and (230.71±40.38) U/L in the control group ( P<0.05). The diastolic blood pressure and systolic blood pressure in the observation group were (84.61±6.29) mmHg 1 mmHg=0.133 kPa and (105.44±7.82) mmHg, respectively, which were lower than the (92.14±7.65) mmHg and (115.51±8.43) mmHg in the control group ( P<0.05), correspondingly. The PT, APTT, and TT in the observation group were all longer than those in the control group, while the FIB was lower than that in the control group ( P<0.05). The incidence of adverse pregnancy outcomes in the observation group (3.85%, 2/52) was lower than that in the control group (19.23%, 10/52), with a statistically significant difference ( P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups ( P>0.05). Conclusions:Nifedipine combined with labetalol has a good effect on patients with gestational hypertension. It can regulate the levels of serum ALP and LAP, reduce blood pressure, improve blood coagulation function and adverse pregnancy outcomes, and reduce the incidence of adverse reactions.
