Objective To investigate the correlation between demodicosis and chalazia in pediatric patients by the use of in vivo confocal microscopy（IVCM）.Methods Retrospective case series.Thirty-five pediatric patients with chalazia and 74 children with normal ocular surface were included from pediatric ophthalmology clinic of Jinan Mingshui eye hospital from January 2021 to June 2022. In vivo laser microscopy has been performed on all subjects to examine the infection of demodex at the root of eyelashes. The the age, gender and demodex infection was collected to analyze the correlation of chalazia and ocular demodex infestation. Results The infection rate of demodex was 91.43% in the observation group and 31.08% in another. There was significant difference between the two groups（χ~2=34.617,P＜0.001）.The OR value was 23.652, and the 95% CI of the overall relative risk was（6.565, 85.217）. There was a good correlation between the demodex and the occurrence of chalazia（V=0.564, P ＜ 0.001）. Conclusion There is a high prevalence of demodicosis in pediatric patients with chalazia, suggesting that ocular demodicosis is a risk factor for chalazia. We should pay attention to the ocular demodicosis in pediatric patients with chalazia.
中心性浆液性脉络膜视网膜病变(CSC)是一种常见的眼底疾病,近期研究显示妊娠期女性发生 CSC 的风险显著增加.妊娠期间,精神压力变化、类固醇类激素水平改变、高血压及血压变异性等多种生理病理因素与 CSC 的发病存在潜在关联.本文综合近年相关的文献报道,阐述了可能参与妊娠期 CSC 发生发展的危险因素,为提高对妊娠期CSC的认识提供一定参考.
变应性鼻炎(AR)是一种 IgE 介导的鼻黏膜慢性炎症性疾病,Th1/Th2 分化失衡是其主要诱导因素,而Th2 免疫反应占优势是AR的主要特点.中医药可通过不同作用机制调节Th1/Th2 细胞分化和相关细胞因子表达或特异性抑制Th2 免疫反应,调节Th1/Th2 免疫失衡的状态,达到治疗 AR 目的.基于此,本文从该角度出发,对近年来中药单体、单味中药和中医经典复方调节Th1/Th2 免疫失衡治疗 AR作用机制进行综述,以期为中医药防治 AR提供理论支持和科学依据.
《中医眼耳鼻喉杂志》是2009年经国家新闻出版总署批准,四川省教育厅主管,成都中医药大学主办的学术性科技期刊.刊期:季刊;开本:大16开64页,面向国内外公开发行,国内统一刊号:CN51-1726/R;国际标准刊号为:ISSN 1674-9006.
