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    Wiener klinische Wochenschrift

    Wiener klinische Wochenschrift

    JournalISSN 0043-5325eISSN 1613-7671中科院 医学 4区

    年发文量

    研究主题

    论文(330148)

    排序
    1Opportunistic PSA Testing is Not the Safe Alternative : Why Austria's Non-Policy on Prostate Cancer Screening Maximizes Harm and Forfeits the Benefits.
    S. Shariat, Sascha Ahyai, S. Aufderklamm, H. Bachler,Pascal Baltzer, Isabella Bauer-Rupp, F. Berndl, E. Compérat, Günter Diem, Christina Dietscher, C. Druml, Harun Fajkovic,

    Austria has never implemented an organized prostate cancer screening program, yet opportunistic PSA testing has been widespread for more than three decades. This has produced the harms of screening without the safeguards of a program: testing outside appropriate age and life-expectancy windows, repeated testing of low-risk men, unnecessary biopsy, overdiagnosis and overtreatment, while generating little systematic information on quality or outcomes. Randomized evidence shows that organized, repeated screening can reduce prostate cancer mortality substantially, whereas opportunistic testing delivers less benefit with more overdiagnosis. Contemporary risk-adapted pathways further improve the balance of benefit and harm: defined start and stop ages, PSA-based risk stratification, MRI before biopsy, targeted biopsy, and active surveillance can reduce unnecessary biopsies and detection or treatment of indolent disease without compromising detection of clinically significant cancer. Europe has therefore moved toward organized, PSA-based screening with MRI as a follow-up test. Austria is now participating in PRAISE-U Plus and has initiated a national multidisciplinary consensus process involving 65 experts from 22 organizations. The policy question is no longer whether Austrian men are being screened-they are-but whether screening remains unstructured or becomes organized, quality-assured and equitable. The evidence supports the latter: invite the right men, stratify risk, biopsy selectively, treat only clinically relevant disease, and measure outcomes systematically.

    2026
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    2The Hidden Burden of Cardiovascular Risk in Working Women : A Preventive Cardiology and Gender-Sensitive Analysis in a Hospital Workforce.
    A. Rab, Christian Stoffel, Alexander Viehhauser, Gabriele Stoiser
    2026
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    3The Hidden Burden of Cardiovascular Risk in Working Women
    Anna Rab, Christian Stoffel, Alexander Viehhauser, Gabriele Stoiser

    Cardiovascular disease (CVD) is the leading cause of death among women, yet female-specific and psychosocial risk determinants are inconsistently integrated into preventive strategies. We describe traditional and female-specific risk factors in female hospital employees. In this single-centre, cross-sectional, exploratory study, 111 women aged 34–70 years (nursing, administrative, medical staff) underwent standardised occupational health assessment of lipids, lipoprotein(a) [Lp(a)], glycated haemoglobin (HbA1c), N-terminal pro-B-type natriuretic peptide (NTproBNP), reproductive history and well-being (WHO-5 Well-Being Index). Voluntary participation may have caused selection bias. Dyslipidemia was present in 58.6

    2026
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    4Opportunistic PSA Testing is Not the Safe Alternative
    Shahrokh F. Shariat

    Austria has never implemented an organized prostate cancer screening program, yet opportunistic PSA testing has been widespread for more than three decades. This has produced the harms of screening without the safeguards of a program: testing outside appropriate age and life-expectancy windows, repeated testing of low-risk men, unnecessary biopsy, overdiagnosis and overtreatment, while generating little systematic information on quality or outcomes. Randomized evidence shows that organized, repeated screening can reduce prostate cancer mortality substantially, whereas opportunistic testing delivers less benefit with more overdiagnosis. Contemporary risk-adapted pathways further improve the balance of benefit and harm: defined start and stop ages, PSA-based risk stratification, MRI before biopsy, targeted biopsy, and active surveillance can reduce unnecessary biopsies and detection or treatment of indolent disease without compromising detection of clinically significant cancer. Europe has therefore moved toward organized, PSA-based screening with MRI as a follow-up test. Austria is now participating in PRAISE-U Plus and has initiated a national multidisciplinary consensus process involving 65 experts from 22 organizations. The policy question is no longer whether Austrian men are being screened—they are—but whether screening remains unstructured or becomes organized, quality-assured and equitable. The evidence supports the latter: invite the right men, stratify risk, biopsy selectively, treat only clinically relevant disease, and measure outcomes systematically.

    2026
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    5Cardiovascular-kidney-metabolic Outcomes in Women with Hypertensive Disorders of Pregnancy at 12 Months Postpartum
    Katharina Findl,Sarah Halmer, Sascha Klee,Constance Busvine, Marion Renner-Sebek,Martin Wiesholzer,Susanne Schubert, Thomas Eiwegger,Barbara Wichert-Schmitt,Birgit Pfaller

    Hypertensive disorders of pregnancy are risk factors for later cardiovascular and chronic kidney disease. Early postpartum trajectories of blood pressure and metabolic recovery in this high-risk population are still insufficiently defined. A prospective, single-center, observational cohort study was conducted in the Cardiovascular-Kidney-Metabolic Women’s Healthcare Prevention Program (PreCareFem) at the University Hospital St. Pölten, Austria. Participants were enrolled on presentation between 1 June 2023, and 31 March 2025. Cardiovascular and metabolic surrogate parameters, including automated blood pressure measurement, anthropometric evaluation, cardiovascular, kidney and metabolic parameters, lifestyle assessment following the components of the “Life’s Essential 8”, and urine albumin-creatinine ratio were assessed peripartum and at 3–6 and 12 months postpartum. A total of 91 women with preeclampsia (PE; n = 66) and gestational hypertension (GH; n = 25) were enrolled. At 12 months postpartum, 31

    2026
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    高被引作者

    作者引用发文
    Stephan Windecker86003361
    Jeroen Bax84900672
    Gregory YH Lip74649738
    Gerasimos Filippatos65770219
    Marco Valgimigli60253134
    Alec Vahanian59686225
    José Luís Zamorano Gómez51956103
    David Matthews50848111
    Fernando J Martinez50736561
    Adnan Kastrati50156275

    高产作者

    作者引用发文
    Christodoulos Stefanadis89381250
    Dimitris Tousoulis5281848
    Gregory YH Lip74649738
    Jeroen Bax84900672
    Filippo Crea28881572
    Patrick Serruys30300562
    Fernando J Martinez50736561
    Thomas F. Lüscher22888527
    Costas Tsioufis10904467
    Jens Juul Holst17361457

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