The researching of the progesterone and prolactin levels in the probes of the tissue from the solid malignant breast tumors T2N0M0 and T2N1M0 and endometriumT1cN0M0 and T2N0M0, benign tumors (fibrocystic disease with nodal growth and hysteromyoma) and combined pathology with breast cancer T2N0M0 and T2N1M0 and hysteromyoma was performed in the group of postmenopausal women. The probes of intact tissue from the mammary glands and endometrium were used as a control. In all probes of the tissue from the breast tumors the prolactin level was increased but the rate of increasing was not similar with the maximum in the group of breast cancer combined with hysteromyoma. The differences in the level of prolactin were founded in the uterine tumors. The maximal level was in the tissue from hysteromyoma along and in combination with breast cancer. In the group of isolating tumors in mammary glands or endometrium the decreasing of progesterone level was in malignant tissue only. There were no changes in the hormone’s level in the probes from the benign tumors (fibrocystic disease with nodal growth and hysteromyoma) by the side of intact tissue. The decreasing of hormone’s level in 1,9 and 2,2 relatively was founded in breast cancer in combination with hysteromyoma in both probes by the side of intact tissues of mammary gland and endometrium.
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