Гистохимическое И Иммуногистохимическое Исследование Внеклеточного Матрикса Фиброзного Кольца Межпозвонковых Дисков При Моделировании Стафилококковой Инфекции

RESEARCH OBJECTIVE: to study the changes of an extracellular matrix of a fibrous ring of intervertebral disks at modelling staphylococcal infection. MATERIAL AND METHODS: 18 males Wistar with tibia bone osteomyelitis and 6 control animals; histochemistry and immunohistochemistry on the basis of the automatic analysis of fibrocartilage image at 1, 2 and 3 months after osteomyelitis development. RESULTS AND DISCUSSION: reorganization of the extracellular matrix of the fibrous ring has been revealed at the long-term staphylococcal infection that is the response to occurring degenerative changes in intervertebral disks.