Исследование Неоколлагеногенеза В Области Имплантации Эндопротеза «parietene ProGrip» В Зависимости От Использования Препарата «Солкосерил»

В.А. Лазаренко,С.В. Иванов,И.С. Иванов,И.П. Парфенов,Г.Н. Горяинова, Н.Р. Пашина, Е.И. Никишина,А.В. Иванов,Е.Г. Объедков

Курский научно-практический вестник «Человек и его здоровье»（2016）

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摘要

Nowadays treating patients with hernia disease is a purely surgical question. Development and introduction of new materials for the replacement will certainly have a positive impact on the treatment of patients with hernias of the anterior abdominal wall, but do not solve the problem of dysplasia of connective tissue structures. The experimental study included 120 white laboratory mice. Animals were divided into two groups, 60 animals each. The division into two groups was due to using "Solkoseril". The effectiveness of "Solkoseril" on the formation of connective tissue was evaluated by counting the I and III types collagen in a paraprosthesis region, determining their ratio and density of connective tissue structures by using polarizing microscopy. The study revealed the collagen stimulating effect of "Solkoseril". The combination of a half-absorbable material for replacement therapy with "Solkoseril" allows to obtain maximum results, both for maturation of connective tissue structures and significant (p ≤ 0.05) increase in their density.

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