Objective To observe the clinical efficacy of omeprazole and rabeprazole with combined treatment on pep tic ulcer.Methods Eighty cases of peptic ulcer patients included by our hospital from January 2010 to December 2011 were randomly divided into control group and observation group.Two groups' patients were all given basic treatment.The control group was given oral omeprazole treatment,and observation group were also given oral rabeprazole treat ment,except for given oral omeprazole treatment same with control group,and then the treatment effect of two groups was observed.Results The total effectiveness of clinical treatment of the observation group was 92.5%,and total effi ciency of clinical treatment of the control group was 80.0%,rhe total clinical efficiency of the observation group was obviously higher than that of the control group,there was significant difference(P0.05);there was no significant difference about the adverse reaction rate of the two groups(P0.05).Conclusion In clinical treatment,the effect of using omeprazole and rabeprazole on combined treatment peptic ulcer is significant,it effectively improves the clinical treat ment effect,and the adverse reactions are relatively small,then it is worthy of application and promotion in clinical practice.

Objective:To investigate the scientific conclusion to prevention and treatment of allergic rhinitis.Methods:90 cases with pediatric allergic rhinitis were randomly divided into three groups,which were group of Cinnamonvine Pill(30 cases)(A group),group of Granule of Jade Screen(30 cases)(B group),and group of Tablet for Rhinitis Cure(30 cases)(C group).A group was treated with Cinnamonvine Pill,B group with Granule of Jade Screen,and C group was treated with Tablet for Rhinitis Cure.All were orally taken.One treatment course included 12 weeks.After 12 weeks′ treatment and 36 weeks′ follow-up the symptoms score,IgE,PAF and clinical effects were observed and contrasted.Results:The total effect of A group was 93.33%(95%CI =77.9%-99.2%),of B group 70%(95%CI =50.6%-85.3%),and of C group 43.33%(95%CI =25.6%-61%).The comprehensive effect of A group was better than of C group(|R1-R3|=0.280 70.186 1,P0.05).After 12 weeks′ treatment and 36 weeks′ follow-up the symptoms score,IgE and PAF parameters were reduced greatly in A group,and much better than B group(P0.01)and C group(P0.01).Conclusion:The curative effect of Cinnamonvine Pill is better than that of Tablet for Rhinitis Cure,OR=0.05(95%CI=0.01-0.27),NNT=2(95%CI=1.36-3.78).And its effect may be better than that of Granule of Jade Screen,OR=0.17(95%CI=0.03-0.85),NNT=4(95%CI=2.33-26.67).

胃食管反流病(gastroesophageal reflux disease,GERD)是指胃食管腔因过度接触(或暴露于)胃、十二指肠内容物而引起的胃食管反流症和食管黏膜损伤的疾病,常表现为反酸、反胃、嗳气、烧心、胸骨后或剑突下疼痛等胃食管症状,也可见咳嗽、哮喘、咽喉炎、声音嘶哑、咽部异物感等食管外症状.反流性食管炎(reflux esophagitis,RE)属于GERD范畴,本病发病率高,严重影响了患者的生活质量,且治疗后复发率很高,如果得不到及时有效的治疗,还会引起食管腺癌、Barrett's食管及食管癌[1-6].

肝胃郁热型胃脘痛是临床常见病,情志不畅,饮食不节,肝胃郁热,气机升降失司是导致本病的主要原因。临床遵叶天士"治胃佐泄肝,制其胜"之意,我们在临床疏肝用四逆散,抑酸用左金丸,两方合用,收到较好的效果。就肝胃郁热型胃脘痛的临床特点及治疗经验进行了总结,为临床运用提供理论依据。