Objective To observe the effect of Yanlurukang Capsules on the breast tissue and expressions of estrogen receptor (ER) and progesterone receptor (PR) in rats with hyperplasia of mammary glands (HMG),and to discuss the mechanism.Methods Breast hyperplasia rat model was established by intramuscular injection of estradiol benzoate and progesterone.The changes of breast tissue were observed in rats of each group.The expressions of ERα,ERβ and PR in breast tissues were detected using immunohistochemical staining.Results Yanlurukang Capsules significantly reduced the layers of mammary ductal epithelial cells and the number of acini in the experimental rats,down-regulated the expressions of ERα and PR,and enhanced the expression of ERβ.Conclusions Yanlurukang Capsules can inhibit HMG in rats,the mechanism may be related to up-regulation of ERβ expression and down-regulation of ERα and PR expressions.

种植体周围炎是导致种植体周围骨组织吸收的主要原因,也是导致种植修复失败的重要因素.Zitzmann等研究认为种植体周围炎发生率为28％～56％.Khoshkam认为,由于研究人群、种植体系统的不同,以及对于种植体周围炎的定义、分类及统计方法不同,各类种植体周围炎发病率差异很大,数据统计为2.7％～47.1％.而林野等研究表明:因种植体周围骨吸收导致种植体脱落,占脱落种植体的97.06％.因此,种植体周围炎的治疗就显得极为重要.本文就种植体周围炎的治疗方法做以下阐述.

胆囊结石是老年人的常见病、多发病,心理干预可以使患者建立信心,调整心态,增强对手术的耐受力,让家属及患者以获得最大的心理支持为目的,根据不同的心理特征,用科学的护理方法积极进行心理疏导和生活习惯的修正,进行针对性的健康教育,可以使患者对腹腔镜胆囊切除术的认识和自我控制能力加强,以预防急性事件的发生.

肠易激综合征(irritable bowel syndrome,IBS)是一种常见的肠道功能性疾病,患者常有腹痛、腹胀、肠鸣、便秘或腹泻与便秘交替等症状,并伴有明显的全身性神经官能症状.其发病与精神因素及应激事件关系密切[1].从肝脾论治本病是中医药防治的重点之一,本文将从分析情志因素与肠易激综合征的关系人手,探讨调肝理脾治疗本病的理论价值.

胃食管反流病(gastroesophageal reflux disease,GERD)是指胃食管腔因过度接触(或暴露于)胃、十二指肠内容物而引起的胃食管反流症和食管黏膜损伤的疾病,常表现为反酸、反胃、嗳气、烧心、胸骨后或剑突下疼痛等胃食管症状,也可见咳嗽、哮喘、咽喉炎、声音嘶哑、咽部异物感等食管外症状.反流性食管炎(reflux esophagitis,RE)属于GERD范畴,本病发病率高,严重影响了患者的生活质量,且治疗后复发率很高,如果得不到及时有效的治疗,还会引起食管腺癌、Barrett's食管及食管癌[1-6].

从1836年开始砷剂就用于牙髓的失活[1].现在砷制剂(三氧化二砷)作为牙髓失活剂已被广泛用于临床,疗效良好,但由于砷制剂的毒性作用,临床上时有砷剂外溢致化学性骨髓炎发生.现将我科收治的1例砷剂通过髓室底穿孔致化学性上颌骨骨髓炎报告如下.

结肠镜检查是目前诊断结肠性疾病最常用和最直接可靠的方法,是诊断疾病的"金指标",也是治疗某些结肠、直肠息肉及出血的有效手段,具有很高的诊断和治疗价值.尤其是无痛结肠镜的临床运用更是使该项技术得到普及,但是因麻醉意外及适应征的限制,尚不能满足所有患者的要求.

<正>前列腺炎是成年男子的一种常见病,临床上可分为急性和慢性,中医学将其归至精浊。我院前列腺科2008年10月至2010年10月间采用中药保留灌肠加熏洗坐浴治疗慢性前列腺炎127例,取得较好的效果。现将护理体会报告如下。1临床资料

Objective To explore the TCM characteristics on phlegm obstruction type hyperlipidemia by clinical classification and hemorheological analysis on 140 patients.Methods Blood samples,attained from the 140 patients diagnosed hyperlipidemia of phlegm obstruction type,were tested on blood lipids and hemorheology for analysis on characteristics and hemorheological changes of the following four subsets as hypercholesteremia,mixed hyperlipidemia,hypertriglyceridemia and low high-density lipoproteinemia,of which relevancies among the four were then analyzed.Results In the 140 cases,the low high-density lipoproteinemia took up the largest proportion,then the mixed hyperlipidemia ranked the second,then the hypertriglyceridemia,and the hypercholesteremia took up the smallest.Total cholesterol(TC) level in hypercholesteremia and triglyceride(TG) level in mixed hyperlipidemia were significantly higher than that in other subsets(P0.01).HDL-C level was obviously lower in low high-density lipoproteinemia than that in other subsets(P0.01).The rest indexes were observed no significant differences(P0.05).LDL-C levels in hypercholesteremia and mixed hyperlipidemia were significantly higher than the rest subsets(P0.01).Comparisons on ApoAI,ApoB,ApoAI/ApoB showed no significant differences among subsets(P0.05).The hemorheological indexes in mixed hyperlipidemia were greater than other subsets(P0.01),in which hypertriglyceridemia was greater than the rest(P0.05).Conclusion Phlegm obstruction type hyperlipidemia is largely seen in low high-density lipoproteinemia.And the mixed hyperlipidemia has most significant hemorheological changes.