艾滋病免费抗病毒治疗是艾滋病防治工作重要组成部分，也是国家对艾滋病患者实施的“四免一关怀”策略的重要内容之一。山西省自2004年开展国家免费艾滋病抗病毒治疗工作，取得了良好的治疗效果[1-3]。为评估艾滋病免费抗病毒治疗效果，现将山西省部分市艾滋病免费抗病毒治疗情况进行效果分析。

Objective To evaluate the effectiveness of free antiretroviral therapy(ART) in adults and the factors influence ART outcome. Methods A retrospective cohort study was conducted Shanxi province. All qualified ART recipients were enrolled in the national free ART program from June 2004 to December 2012. Statistical analysis was conducted by SPSS software (version 19.0), use the t test and chi-square test, with Cox regression model for survival analysis. Results One thousand eight hundred and eighty-seven cases were included in the study. The rates for participants, who survived, who were deceased for acquired immune deficiency syndrome (AIDS) related diseases, who withdrawal from the treatment, who transferred to other hospital and who lost for follow-up were 83.1%, 13.5%, 1.4%, 1.2% and 0.8%, respectively. The cumulative survival rates were 0.91, 0.89, 0.88, 0.86, 0.85, 0.82, 0.80, 0.79 and 0.79 at 0.5, 1.0, 2.0, 3.0, 4.0, 5.0, 6.0, 7.0 and 8.0 years after treatment initiation, respectively. The medians of CD4+T cell count were 143.5 cells/μL prior to treatment and 205.3 cells/μL post treatment. 18.2% of ART recipients had their viral loads below detection limit before therapy and this percentage increased to 89.1% after therapy. In the multivariate Cox proportional hazard model, CD4+T cell count and BMI before treatment initiation, and the age start therapy were significantly associated with survival time. The Hazard ratio was 4.05, 3.44 and 3.68, respectively. Record the count of CD4+T lymphocyte after antiretroviral treatment, the difference of CD4+T lymphocyte count between before antiretroviral treatment and after, 3 covariates had been produced by the viral load program generates after antiretroviral treatment , 15 variables had been proved to be statistically and professional significance before antiretroviral treatment. Analysis above all variables based on multi factor time-dependent Cox regression model. There were statistical differences between the count of CD4+T lymphocyte after antiretroviral treatment and the survival time (HR=30.28). Conclusion The ART treatment has been successfully implemented with the significant improvement on immune system and containment of viral replication.

目的:通过分析现代社会传染病的流行原因,探讨防控策略。方法:根据近些年全国传染病流行的实际情况,分析并探讨传染病在我国现阶段流行的主要原因,并提出相应的防控策略。结果:传染病的防控与全民对传染病的防控意识有关。结论:控制传染病疫情,必须增强全民对传染病的防控意识,坚持防治结合的原则;继续完善疫情监测网络,保障通畅的信息通道;继续加强医务人员的专业知识培训,建立健全突发公共卫生事件应急机制。

目的:通过监测、掌握城区性病的发病现状,为大同市性病防治工作措施的制定提供依据。方法:根据《全国性病监测方案》的要求,对大同市城区性病高危人群进行梅毒抗体检测,然后对检测结果进行数据整理,采用SPSS软件分析。结果:2008-2011年,大同市城区共检出梅毒75例,检出率为4.69%。结论:我市大力扫黄和美沙酮门诊的开展降低了一些社会丑恶现象的发生率,从客观上将性病疫情控制在较低水平。有关性病防治知识宣传力度的加大使群众对性病防治知识的掌握程度和自我保护意识都有了很大的提高,这也是疫情得到控制的一个重要因素。无业人员是性传播疾病的主要受害者,也是性病防治工作的重点人群,应充分发挥社区组织的作用,加大全人群的性病防治宣传干预力度。教育部门应加强生理卫生教育,特别是性健康教育,有效遏制青少年学生未来性病的发生。

Objective To understand the characteristics of AIDS epidemic in Datong in Shanxi.Methods By using national AIDS comprehensive prevention and control information system,the analysis was conducted on the data of HIV/AIDS cases,both local cases and cases from other provinces,in Datong from 1996 to 2009.Results During this period,143 HIV/AIDS cases were reported,including 116 HIV infection cases and 27 AIDS cases,and 22 cases were fatal.Among these HIV/AIDS cases,77 were from other provinces and 66 were local people.Among 66 local cases,15 were fatal,2 were out of follow up and 14 were found to be false.The remaining 33 cases were in follow up.The survey indicated that among the population(3.2 million) in Datong,29 HIV infection cases were detected with the infection rate of 0.91/lakh and 23 AIDS cases were detected with the prevalence of 0.72/lakh.Totally 42 villages(street) in 27 townships in 10 counties(district) were affected by AIDS epidemic.The cases were mainly found in urban area,mine area and southern suburb.Conclusion The AIDS epidemic was at low level stage in Datong,the first incidence peak was observed.The main transmission route was sexual contact.The severity of AIDS epidemic differed in different area in Datong.

目的了解大同市艾滋病流行现状及流行趋势、不同人群流行特点。方法采用哨点监测、流行病学调查、重点人群筛查以及本市监测网络逐年上报的资料。结果1996~2006年共监测各类重点人群290429人次,报告确认HIV抗体阳性者65例。本市感染者28例,AIDS现症病人6例,死亡5例。结论大同市仍处于艾滋病低流行期。

如今在茶余饭后、农闲之时,当你走进江苏省响水县的各乡(镇)村,你再也看不到昔日闲谈、吹牛、搓麻将磨时光的情景,你定会发现,越来越多的青年民兵们凝神静坐在墨香萦绕的"青年民兵之家"开设的"国防科技茶座"中,倘徉在书海里汲取知识的琼浆,索取科技致富的办法.青年民兵们沏上一杯茶,看看国防、科技录像,读读科技、国防报刊,切磋切磋各自种植养殖致富心得,相互传经探宝……这是笔者近日在江苏省响水县各乡(镇)村看到的喜人景象.