为满足当前经济发展对专业人才的要求,创新应用型人才的培养是高等学校教学工作的重点,"分析方法选择及方案设计"课程是江苏理工学院应用化学专业开设的专业核心课,作者从教学目标的定位、教学内容的选择、教学方法的创新、考核方式的优化等几个方面对课程进行了教学探索,希望能够为学生综合实践能力的提高、教学质量的提升、相关课程的教学和改革提供思路与借鉴.

科技创新是驱动社会发展、增强综合国力的永恒动力。培养并造就具有强大科技创新能力的人才队伍是新时代下高等学校面临的重大又颇具挑战性的任务。因此，如何提高大学生的科技创新能力十分重要。在教育教学活动中基于“翻转课堂教学—实验室（或研究室）开放——学生课题立项—学科（或专业）竞赛—毕业设计（论文）”五位一体的集成模式下培养大学生的科技创新能力，以期激发学生的创新思维，提升人才培养质量，为相关教学改革提供思路与借鉴。

The metal doping at the Pb2+ position provides improved luminescence performance for the cesium lead halide perovskites, and their fabrication methods assisted by microwave have attracted considerable attention due to the advantages of fast heating and low energy consumption. However, the postsynthetic doping strategy of the metal-doped perovskites driven by microwave heating still lacks systematic research. In this study, the assembly of CsPbBr3/CsPb2Br5 with a strong fluorescence peak at 523 nm is used as the CsPbBr3 precursor, and through the optimization of the postsynthetic conditions such as reaction temperatures, Mn2+/Pb2+ feeding ratios, and Mn2+ sources, the optimum Mn2+-doped product (CsPb(Cl/Br)(3):Mn) is achieved. The exciton fluorescence peak of CsPb(Cl/Br)(3):Mn is blueshifted to 437 nm, and an obvious fluorescence peak attributing to the doped Mn2+ ions at 597 nm is obtained. Both the CsPbBr3 precursor and CsPb(Cl/Br)(3):Mn have high PLQY and stability because there are CsPb2Br5 microcubic crystals to well disperse and embed the CsPbBr3 nanocrystals (NCs) in the precursor, and after Mn2+-doping, this structure is maintained to form CsPb(Cl/Br)(3):Mn NCs on the surface of their microcrystals. The exploration of preparation parameters in the microwave-assisted method provides insights into the enhanced color-tunable luminescence of the metal-doped perovskite materials.

分析化学是高校重要的专业基础课之一.本文以江苏理工学院环境科学专业为例,针对分析化学课程教学现状,从优化教学内容、多种教学方法并举、开展线上线下混合式教学以及优化考核方式等方面,探讨了分析化学课程教学改革措施,以期达到激发学生学习兴趣,提高教学质量,增强学生综合能力的目的.

3D monolithic reactor has shown great promise for varied heterogeneous catalysis reactions including water treatment, energy generation and storage, and clean fuel production. As a natural porous material, macroporous wood is regarded as an excellent support for inorganic catalyst due to its abundant polar functional groups and channels. On the other hand, a metal organic framework (MOF) has been widely used as heterogeneous catalyst due to its high specific surface area and large amount of microporosities. Combining macroporous wood and a microporous MOF is expected to produce a high-performance 3D reactor and is demonstrated here for Fischer-Tropsch synthesis. The carbonized MOF/wood reactor retains the original cellular structure with over 180 000 channels/cm2. When being decorated with hexagonal-shaped core-shell Co@C nanoparticles aggregates derived from Co-MOF, the MOF/wood reactor resembles a multi-cylinders reactor for Fischer-Tropsch synthesis. Because of the unique combination of macro- and microporous hierarchical structure, the 3D MOF/wood reactor demonstrates exceptional performance under high gas hourly space velocity (81.2% CO conversion and 48.5% C5+ selectivity at 50 L·h-1·gcat-1 GHSV). This validates that MOF/wood can serve as a multi-cylinders and high-power reactor for catalytic reactions, which is expected to be applicable for environmental and energy applications.

As a new type of fluorescent probe, metal nanoclusters have a broad application prospect in optical sensors and biosensors. In the present study, copper nanoclusters (CuNCs) have been synthesized by etching non-luminescent copper nanoparticles with excess cysteine (Cys). The as-prepared cysteine stabilized turquoise emitting copper nanocluster (Cys-CuNCs) exhibited strong fluorescence emission, and could be quenched by Fe3+ ions. After adding quinolones (QNs) to the quenching system, the fluorescence intensity of Cys-CuNCs was restored. A novel Cys-CuNCs-Fe3+ sensor for the detection of QNs, such as ofloxacin (OFL) and norfloxacin (NOR), was constructed based on the fluorescence turn-on strategy. The linear range of the proposed method is 0.5?40 ?M for OFL and 0.5?50 ?M for NOR, and the detection limits of OFL and NOR are all 50 nM. As a cost-effective, high selectivity and sensitivity sensor tool, the Cys-CuNCs-Fe3+ sensor had been successfully applied to detect QNs in tablets and human urine.

在互联网技术的飞速发展下,混合式教学成为了一种新的教学方式."雨课堂"教学平台是传统教学和网络教学相结合的产物,不仅可以激发学生学习的主动性,同时,也是缩短师生沟通路径、提升课堂教学效率的重要手段.借助"雨课堂"教学平台,探讨了如何在分析化学课程教学中将课前准备、课堂教学、问题反馈等环节应用"雨课堂"构建混合式教学."雨课堂"教学平台的应用推广需要高校和师生的共同努力,并以之推动教学改革的发展.

With houttuynia cordata as carbon source, photoluminescent carbon quantum dots (CDs) were obtained via a one-step hydrothermal procedure. The absorption band of metronidazole (MNZ, maximum absorption wavelength at 319 nm) can well overlap with the excitation bands of CDs (maximum excitation wavelength at 320 nm). A fluorescent approach has been developed for detection of MNZ based on the inner filter effect (IFE), in which as-prepared CDs act as an IFE fluorophore and the MNZ as an IFE absorber. We have investigated the mechanism of quenching the fluorescence of CDs and found that the IFE leads to an exponential decay in fluorescence intensity of CDs with increasing concentration of MNZ, but showed a good linear relationship (R 2 = 0.9930) between ln(F 0/F) with the concentration of MNZ in the range of 3.3 × 10-6 to 2.4 × 10-4 mol L-1. Due to the absence of surface modification of the CDs or establishing any covalent linking between the absorber (MNZ) and the fluorophore (CDs), the developed method is simple, rapid, low-cost and less time-consuming. Meanwhile, it possesses a higher sensitivity, wider linear range, and satisfactory selectivity and has potential application for detection of MNZ in pharmaceutical preparations.

Silver, as a cheaper and good conductivity noble metal, has successfully been decorated on SnO2 nanoparticles to structure the Ag-SnO2 composites by a facile hydrothermal and in situ reduction method. The difference of structure and properties between SnO2 and composite was characterized by XRD, FESEM, elemental mapping, UV–vis spectroscopy, BET and XPS surface analysis. The sensing performance of SnO2 and composite to formaldehyde were also examined. The composite of 3.7 wt% Ag decorated SnO2 not only exhibits the high response to 10 ppm of formaldehyde but also has better stability and selectivity at an operating temperature of 125 °C. Moreover, the detection limit of the composite was determined to be 0.53 ppm, which is lower than that of pure SnO2 nanoparticles. The response mechanism of the composite to formaldehyde was also discussed in detail, which is attributed to the catalytic effect and the spillover effect of Ag nanoparticles.

In this study, a simple and rapid polymer monolith microextraction procedure was developed for the determination of Cr(iii) ions by inductively coupled plasma-atomic emission spectrometry. A monolithic column modified with cysteine was synthesized and characterized by scanning electron microscopy, Fourier-transform infrared spectroscopy, X-ray photoelectron spectroscopy, thermal gravimetric analysis, specific surface area analysis and pore size distribution analysis. The influences of analytical parameters such as sample pH, adsorption time, eluent type, and coexisting ions were examined. The limit of detection (LOD) and limit of quantification (LOQ) for Cr(iii) ions were 0.005 μg mL-1 and 0.017 μg mL-1, and the relative standard deviation (RSD) was 7.4% (n = 5). The prepared cysteine functionalized monolithic column displayed good enrichment capacity and was successfully applied to the determination of Cr(iii) ions in real samples.

Bio-renewable lignin has been used as a carbon source for the preparation of porous carbon materials. Nevertheless, up to now, there are few studies about the influence of molecular weight of lignin on the structure and morphology of the ordered mesoporous carbon. Here, we synthesized the ordered mesoporous carbon derived from different molecular weights of lignin and Pluronic F127. Fortunately, we found that molecular weight is an important factor for obtaining highly ordered channels, high specific surface area, and ordered mesoporous carbon. More importantly, the narrow well-defined mesoporous channel could exert a spatial restriction effect to some extent, which can serve as nanoreactors for efficient reactions and enhance catalytic performance. The highly ordered mesoporous carbon from lignin is a good candidate for Fischer-Tropsch synthesis catalyst supports.

Graphitic carbon nitride (g-C3N4) is considered as an attractive, efficient and newly generated photocatalyst material owing to its distinct properties such as metal free, suitable band gap and high physicochemical stability. Nevertheless, the photocatalytic activity of pure g-C3N4 was limited by the fast recombination rate of photoinduced electron–hole pairs and relatively low specific surface area. In this study, we provide a new prospect to overcome the problem by using another suitable precursor urea-assisted copolymerization with thiourea which is expected to optimize the process of thermal condensation, inhibit agglomeration and improve the specific surface area; meanwhile, the formed isotype heterogeneous junction effectively inhibits charge carrier recombination. The formed g-C3N4 isotype heterojunction photocatalyst manifested significant improvement photocatalytic hydrogen production than the single and pure g-C3N4 sample. This significant enhanced photocatalytic performance is mainly ascribed to inhibited recombination, enriched active site and enlarged specific surface area.

为深化教育改革,加强人才培养,以江苏理工学院教学目标为背景,结合分析化学课程本身的特点,提出教学内容应理论联系实际,突出重点难点;教学方法应改变灌输式教学,合理运用多媒体手段;教学模式应连接学术前沿,开展创新实验等分析化学课程教学改革的思路和方法.

A new terbium sensitized spectrofluorimetric method was developed for the determination of trace amounts of dopamine (DA) using ethylenediaminetetraacetic acid as co-ligand and cetyltrimethylammonium chloride as sensitizer. UV absorption and fluorescent spectra were used to investigate the photophysical properties of the ternary complex. Under the optimum conditions, the enhanced fluorescence intensities of the Tb(III) complexes increased linearly with the concentration of DA over the ranges 8 × 10–8–5 × 10–5 M and the limit of detection for DA was found to be 2.4 × 10–8 M. The proposed method has been applied for the quantitative determination of DA in a pharmaceutical preparation and urine samples. The possible energy transfer mechanisms in the lanthanide complexes were discussed.

A simple and sensitive method for the determination of gatifloxacin (GFLX) is developed by using flow injection analysis with potassium permanganate-sodium sulfite chemiluminescence (CL) detection based on the energy transfer from GFLX to terbium(III). Intense signal instead of the weak CL produced by potassium permanganate-sulfite-GFLX system can be observed when Tb(III) is added to the system. A narrow and intense emission band at 545 nm arising from the excited-state Tb(III) was obtained. Under the optimum conditions, a linear range was 5.0 × 10−8 to 8.0 × 10−6 M and the detection limit was 3.2 × 10−9 M. The method has been successfully applied to the determination of gatifloxacin in drug formulations, urine and serum samples. There was no interference from some common excipients used in pharmaceutical preparations. The possible energy transfer mechanisms in the lanthanide complexes were discussed.

With the purpose of further improving students′professional skill,cultivating creativity and employ-ability,application-orientated universities are trying to build a teaching mode for talents cultivation that can be suitable to their own actual situation and local economic construction and social development.This paper analyzes vocational ability of chemical analyzer.Combining the present situation of Jiangsu University of Technology and its cultivating objectives,careful choice the experiment content,increase the application pro-ject and establishment scientific evaluation standard,the quality and level of talents development is improved.

The effect of Acidithiobacillus ferrooxidans on copper recovery in wastes printed circuit boards( PCBs) was investigated. PCBs addition times and amounts adversely inhibited bacterial growth and thus lowered copper leaching capacity,therefore multiple point's addition strategy could improve leaching copper and reduce inhibition of cell growth. The results showed that when multiple PCBs additions 18 g / L( 4 g/L at 48 h,6 g/L at 96 h and 8 g/L at 144 h) were developed,copper extraction reached 80% after240 h cultivation. The suggesting strategy of copper leaching from waste PCBs was feasible and effective.

In the previous research, the effects of different addition time and amount of printed circuit boards (PCBs) on cells growth and metals recovery in separated and mixed culture of Acidithiobacillus thiooxidans and Acidithiobacillus ferrooxidans were investigated. This paper aimed to optimize mixed culture of both acidophiles for maximizing PCBs addition amounts and copper leaching percentage simultaneously. Initially, influences of inoculums ratio between two acidophiles on their cells growth were studied. Then, initial medium pH and concentrations of FeSO4 · 7H2O and elemental sulfur (S(0)) were optimized by response surface methodology (RSM) to improve copper recovery. Finally, multiple-point PCBs addition was tested to determine maximal amounts. Results showed that with initial inoculums ratio (Af:At) 1:2, pH 1.56, FeSO4 · 7H2O and S(0) at 16.88 and 5.44 g/L, and PCBs addition 28.8 g/L, copper recovery reached 92.6% after 240 h cultivation. It was indicated that copper could be efficiently leached out from increased PCBs addition amount and FeSO4 · 7H2O was remarkably reduced from 22.1 to 16.88 g/L.

以聚丙烯腈和苯磺酰胺为原料合成了一种含苯磺酰基酰胺的螯合纤维,讨论了反应时间、温度及反应物配比等因素对反应的影响,用红外光谱对产物的结构进行了确证。利用螯合纤维分离柱从水溶液中分离富集痕量的Pd（Ⅱ）离子,用电感耦合等离子体原子发射光谱仪检测,回收率在95%以上;考察了螯合吸附剂的富集酸度,洗脱条件和吸附容量等吸附性能,结果表明,制备的螯合型吸附剂对Pd（Ⅱ）离子的吸附性能良好。

Ellagic acid (EA), one of the polyphenols in fruits and nuts, has pharmacological activity. To explore binding behavior of EA to protein, human serum albumin (HSA) was chosen and investigated by fluorescence spectroscopy, Fourier transform infrared (FT-IR) spectroscopy and molecular modeling in aqueous solution. Fluorescence titration results indicated that EA effectively quenched the intrinsic fluorescence of HSA by static quenching and the binding process was spontaneous. According to the Scatchard equation, there was only one class of binding sites can bind to HSA, the binding constants at three different temperatures (298, 310 and 318 K) were 8.47 × 104, 7.39 × 104 and 6.00 × 104, respectively. It was found by FT-IR spectra that EA altered HSA secondary structure. Thermodynamic analysis showed that hydrophobic interaction and hydrogen bonds played an important role in stabilizing EA–HSA complex. A molecular docking study suggested that the HSA residues for EA binding located in sub-domain IIA.