The effect of vasopressin given simultaneously with a water load was studied in healthy human volunteers. During maximal water diuresis induced by oral water load of 20 ml water per kilogram body weight, the excreted water fraction was 12.4%, whereas the excretion of osmotically free water was 10.0 ± 1.8 ml/min per 1.73 m 2 of body surface area. These data suggest that the secretion of arginine vasopressin by the neurohypophysis was almost completely blocked. A water load simultaneously with 8 μg sublingual or 0.2 mg oral desmopressin caused a strong and long-lasting antidiuretic response accompanied by a drastic increase in the reabsorption of osmotically free water in the kidneys. It was shown that the magnitude and the time course of the antidiuretic response to therapeutic doses of desmopressin depended on the mode of its administration.
The phenomenology of the instability of charged and uncharged drops and liquid menisci at the end of a capillary through which liquid is fed in constant and variable external electric fields, both uniform and nonuniform, is considered. Methods of investigating such instability are described. The steady-state deformation of drops in electric fields, the critical conditions under which their charged surface loses stability, and the laws of electrical dispersion of liquids in the final stage of instability are discussed.
A method of reducing a system of vector equations of the hydrodynamics of a viscous fluid in orthogonal curvilinear coordinates to an equivalent system of scalar equations is proposed. A problem concerning capillary oscillations and the stability of a spherical charged, electrically conducting highly viscous drop is solved.
A model is proposed for electrical discharge from a water droplet, which explains the experimentally observed formation of a sharp projection at the top of the droplet and emission therefrom of highly dispersed charged droplets and ions.
During the 120-day observations of the state of the tibia under conditions of antiorthostatic hypokinesis and various regimes of motor activity and pharmacotherapy we noted a considerable variability of the acoustic properties of the bone (ultrasonic diagnosis) and mineral component content (photon absorptiometry).
The service properties of M-20BP oil (specification TU 38-1-295-69) can be improved substantially by the addition of an ashless dispersant.