The aim of this study was to make a risk estimation of reproductive pathology among women, who work in a factory of nuclear industry under the long term exposure to low dose ionizing radiation. The medical examination of female personnel of Siberian chemical plant was performed. The ionizing radiation feature and individual associated factors were considered. In the result several risk factors of reproductive pathology were revealed. These were the age of women at the time of starting their exposure and the length of exposure. In the case of starting the exposure of low dose gamma irradiation in early childbearing age the risk of reproductive pathology was doubled and did not depend on the total dose of irradiation.

The frequency and structure of the reproductive system diseases of the woman-workers, who occupied in nuclear industry and who were exposed to ionizing radiation over the small dose range (main group, n=424), were compared with analogous data, which were obtained from woman-workers, who were exposed to unhealthy chemical agents (group of inner control, n=556) and woman-workers who weren't exposed to hazardous industrial factors (group of outer control, n=474). Th e rates of the reproductive system diseases in the main group, especially the rate of climacteric syndrome, were signifi cantly higher as compared with others groups (р=0,029 and р

Summary. Th e frequency and structure of the reproductive system diseases of the woman-workers, who occupied in nuclear industry and who were exposed to ionizing radiation over the small dose range (main group, n=424), were compared with analogous data, which were obtained from woman-workers, who were exposed to unhealthy chemical agents (group of inner control, n=556) and woman-workers who weren't exposed to hazardous industrial factors (group of outer control, n=474). Th e rates of the reproductive system diseases in the main group, especially the rate of climacteric syndrome, were signifi cantly higher as compared with others groups (р=0,029 and р<0,001 correspondingly). We have not revealed any dependence between the frequency of the reproductive system diseases and the level of total dose of external radiation

The aim of this study was to examine prevalence and structure of gynecologic pathology in female workers who work in Siberian chemical plant and who were exposed to continuous professional irradiation in ?small? dose range depending on time of starting and length of radiation exposure. In the women with gynecologic pathology who were exposed ionizing gamma radiation in ?small? dose range, duration of professional irradiation was significantly higher as compared with healthy women who were also exposed ionizing gamma radiation in the same ?small? dose range. Both early onset of radiation exposure and long-time radiation exposure were associated with increased risk of gynecologic pathology development.

Population health is greatly determined by social factors, mode of life, ecological situation, amount and quality of medical assistance. The analysis of reasons of health troubles increase in population should be done taking into account the above aspects. Main consideration should be given to the development of measures aimed at the highest possible decrease of technogenic and anthropogenic factors influence on a human. Thereupon a complex programme of main diseases screening and monitoring in the personnel of the Siberian Group of Chemical Enterprises (SGCE) to be the biggest one among Russian atomic plants has been developed. The purpose of the present paper is to determine main diseases at the earliest stage, the decrease of death rate, as well as the complex estimation of technogenic factors influence on the personnel of radiation dangerous plants and their offsprings. In this case a long-term effect of low doses seems to be the main risk factor. Taking into account the structure of death rate causes of the population of industrialized countries as well as the spectrum of stochastic effects of ionizing radiation, the screening of cardiac ischemia and arterial hypertension, localization of cancer and congenital malformations have been chosen as the program priorities. Algorithm of instrumental laboratory screening of a particular disease includes modern diagnostic tests. Groups at risk are formed taking into account a complex of exogenous and endogenous risk factors (age, chronic diseases, bad habits, length of service at a radiation dangerous plant, dose loads, hereditary factors) and on the basis of the screening examination results. The information obtained is entered in the list of database of the Regional Medicodosimetric Register of the SGCE personnel and Seversk residents followed by analysis and monitoring of groups at risk. Population health is greatly determined by social factors, mode of life, ecological situation, amount and quality of medical assistance. The analysis of reasons of health troubles increase in population should be done taking into account the above aspects. Main consideration should be given to the development of measures aimed at the highest possible decrease of technogenic and anthropogenic factors influence on a human. By the development of modern strategy of public health maintenance it is necessary to take into account the structure of morbidity and mortality rate, their tendencies in a definite group of people as well as the main factors that can influence on the occurrence and development of main diseases. At present a steady tendency to the increase in morbidity rate with non-infectious diseases is recorded in industrialized countries worldwide. Among the death causes cardiovascular and cancer diseases prevail. The problem of increased morbidity rate with malignant neoplasms is of great importance. In spite of new methods developed to reveal and treat cancer diseases the situation is of no change. An overwhelming majority of sick people with a primary established diagnosis of malignant neoplasm (especially those with visceral localization) have locally advanced or generalized tumour process that causes a high rate of one-year mortality and low rate of five-year survival. Taking into account a tendency of cancer diseases occurrence in younger age and the expenses necessary to treat patients using up-to-date high-tech methods it is obvious that the problem of treating cancer diseases is no more a medical problem but is of a universal character touching both economical and social spheres of life. All mentioned above refers to cardiovascular diseases as well. According to the WHO data arterial hypertension and ischemic heart disease make up 35% of all cardiovascular diseases. About 38 mln.