Objective : to investigate the colorectal adenomas polyp tissues in the expression of interleukin-17(IL-17) and its clinical significance.Methods : using immunohistochemical SP method to detect 88cases of colorectal adenomas polyp tissues in the expression of IL-17,and analyze its expression level and the clinical pathological characteristics of the relationship.Results : IL-17positive expression rate of colorectal adenomas polyp tissues was higher than the normal intestinal mucosa [(17.03 + 5.87) % vs(2.34 + 1.27) %,P <0.05 ];In colorectal adenomas polyp tissues IL-17positive expression rate : has nothing to do with age,sex(P>0.05),a CVS above tubes and tubular villi of polyps,greater than or equal to 1cm in diameter than the diameter of less than 1cm of polyps,severe dysplasia is higher than that in mild and moderate atypical hyperplasia polyps,rectum,rectum is higher than other parts of the border areas of polyps.Conclusion : IL-17May be colorectal adenomas sex polyp occurrence,development and important promoting factor in the process of cancer for colorectal adenomas sex polyp canceration prediction has important meaning.

<正>资料与方法临床资料慢性盆腔炎患者60例,其中30例用金刚藤胶囊配合微波治疗,30例用妇炎康片配合微波治疗。两组具有不同程度的小腹疼痛、带下量多、腰骶酸痛、神疲肢软、肛门下坠、月经量

目的:探讨bcl-2和bad基因在血管瘤组织中的表达及相关性.方法:采用免疫组织化学方法检测人皮肤血管瘤增生期、退化期及正常皮肤组织中bcl-2和bad基因的表达水平.结果:Bcl-2在增生期血管瘤内皮细胞的表达明显高于退化期血管瘤内皮细胞和正常皮肤组织血管内皮细胞(P＜0.01);Bcl-2在退化期血管瘤内皮细胞的表达与正常皮肤组织血管内皮细胞相比,差异无显著性(P＞0.05).bad在退化期血管瘤内皮细胞的表达明显高于增生期血管瘤内皮细胞和正常皮肤组织血管内皮细胞(P＜0.01).结论:bcl-2和bad参与了血管瘤的发生、发展和退化;Bcl-2通过抑制内皮细胞凋亡而促进血管瘤的增生;bad通过诱导血管瘤内皮细胞的凋亡而促进血管瘤由增生向退化的转变.

医用X射线在医疗卫生领域得到广泛应用.人们在接受X线检查的同时,也受到一定程度的伤害.因此,2006年3月1日国家颁布了《放射诊疗管理规定》,旨在加强放射工作管理,这也对X射线的防护工作提出了更多更高的要求.

目的:探讨促凋亡基因bad在皮肤血管瘤中的表达及其与临床的关系。方法:采用免疫组织化学方法检测人皮肤血管瘤增生期、退化期及正常皮肤组织中bad的表达水平,利用计算机图像分析技术测量不同时期血管瘤组织和正常皮肤组织bad表达的平均光密度和平均阳性面积。结果:图像分析结果显示,增生期组的平均光密度为0.0496±0.0152;退化期组的平均光密度为0.1751±0.0349;正常皮肤组的平均光密度为0.0524±0.0164。增生期组的阳性面积率为0.1047±0.0103;退化期组的阳性面积率为0.2943±0.0371;正常皮肤组的阳性面积率为0.1103±0.0132。经q检验,退化期组与增生期组、退化期组与正常皮肤组之间,bad的平均光密度及阳性面积率有显著性差异(P<0.01),增生期组与正常皮肤组之间平均光密度及阳性面积率的差异无显著性(P>0.05)。结论:bad通过诱导血管瘤内皮细胞的凋亡而促进血管瘤由增生向退化的转变。

2004～2005年在我院门诊产检及住院分娩的HBsAg(+)孕妇224例,在知情同意的情况下进行HBIG注射阻断HBV母婴传播,效果分析如下.

Objective: To inject HBIG before delivery for the HBsAg(+) pregnant women,then observe their neonates about status of HBV infection.To evaluate the interruptive effect of HBIG.Methods: 448 HbsAg(+) pregnant women were randomly divided into HBIG group and control group.Each subject in the HBIG group received 200 IU HBIG intramuscularly injection at 32 weeks,36 weeks and 40 weeks of pregnant.The subjects in the control group did not receive any specific treatment.Blood tests were performed for all the lying-in women and their neonates.Blood specimens were tested for HBsAg,HBsAb,HBeAg,HbeAb,and HbcAg by enzyme immunoassay,and HBV-DNA by PCR.All newborn infants received passive and active immunity of HBV.Results: The rates of intrauterine transmission in the two groups(HBIG group and control group) were 5.3% and 14.5% respectively(χ~2= 10.675,P<0.001).Conclusions: HBV infection of mother-to-child may be interrupted by injecting multiple intramuscularly HBIG injections before delivery.

目的:观察腹腔镜联合药物二甲双胍及氯米酚与二甲双胍及氯米酚治疗多囊卵巢综合征(PCO S)疗效比较。方法:对确诊为PCO S患者随机分成两组:研究组(n=50例)采用腹腔镜联合药物治疗;对照组(n=45例)采用药物治疗。疗程半年,治疗前后抽血查黄体生成素(LH)、卵泡刺激素(FSH)、睾酮(T)、雌二醇(E2)及空腹血糖(FG)、空腹胰岛素(F ins),观察月经、排卵、妊娠情况。结果:在以上6种指标中,LH、T、F ins治疗前后差异有显著(P<0.01),FSH、E2、FG差异无显著(P>0.05),两组比较月经恢复及排卵情况差异无显著(P>0.05),但妊娠率差异有显著(P<0.01)。结论:两组比较在改善月经、排卵等方面作用相似,但腹腔镜联合药物组妊娠率高些。