目的:研究金天格胶囊对于老年性骨质疏松症的临床疗效.方法:将100例受试者随机法分为两组,对照组(46例):阿尔法骨化醇软胶囊+钙尔奇D片口服,治疗组(54例):在对照组基础上辅以金天格胶囊口服,并对治疗后3、6月进行临床疗效评价.比较治疗前后股骨Ward三角骨密度、情况.结果:治疗3月和6月后,治疗组骨痛减轻情况明显优于对照组(P＜0.05).治疗6月后,治疗组骨密度提高明显高于对照组,差异有统计学意义(P＜0.05).结论:金天格胶囊能有效促进骨生长,缓解骨质疏松症引起的骨骼疼痛,是治疗老年性骨质疏松症的有效药物.

Objective:To improve the osteoarthritis (Osteoarthritis, OA) model, osteoporosis (Osteoporosis, OP) model, the estrogen in serum of rats were observed in the change detection (E2), femur proximal bone density of rats, to investigate the effect of estrogen on OA, OP, observe the changes of Bushen Tongluo Decoction intervention serum E2, OA, OP in order to study the pathogenesis of common. Methods: 50 April old female SD rats, were randomly divided into 5 groups:blank control group, OA group (Hulth process), OA+Bushen Tongluo Decoction group, OP group (ovariectomy), OP+Bushen Tongluo Decoction group, 10 rats in each group, the rats were killed after 8 weeks, the right femur were observed rat proximal bone density, the content of serum estrogen. Results:the contents of OP rats proximal femur bone mineral density, serum E2 was lower than the control group, the difference was statistically significant (P<0.05), The effect of Bushen Tongluo Fang intervention, content of proximal femur bone mineral density, serum E2 was higher than that of model group of corresponding. conclusion:The incidence of estrogen on OA, OP has important effect, bone density by Bushen Tongluo can improve SD rats OA, OP model of the proximal femur, increase the content of serum estrogen, the OA and OP may be the mechanism of balance between the influence factor in vivo cytokine activity and cell increasing the concentration of serum estrogen, exert their therapeutic effects.

目的:探讨活血通络法治疗儿童股骨头坏死的疗效。方法:观察26例儿童股骨头缺血性坏死患者使用中药的3、6、12月治疗效果。结果:第3、6、12月疗效不同(P<0.05),有效率分别为65.4%,80.7%,88.5%,有效率总体在提高,不同临床分期疗效不同(P<0.05)。结论:活血通络法对儿童股骨头缺血性坏死有较好的治疗作用。