Objective To compare the efficacy and toxicity of paclitaxel plus FOLFOX4 regimen and FOLFOX4 regimen in the treatment of patients with advanced gastric carcinoma(AGG).Methods A total of 63 patients with AGC were randomized into two groups.Two or more cycles of chemotherapy were completed.Group A consisted of 32 patients who received paclitaxel plus FOLFOX4 regimen and group B consisted of 31 patients who received FOLFOX4 regimen.Results The response rates(CR + PR) of groups A and B were 43.7% and 35.5% ,the median TTP was 5.87 and 3.9 months,and the median survival time of patients was 9.8 and 8.5 months,respectively.The response rates of the 2 groups had no significant difference(P > 0.05).The median TTP and the median survival time had significant difference(P <0.05).The major side effect of the two groups had significant difference(P < 0.05).Conclusion Paclitaxel plus FOLFOX4 regimen is an effective,acceptable and safe method for treatment of patients with advanced gastric cancer.

我院2003-01/2005-06对肝癌行肝动脉介入化疗,取得了较好的近期疗效,现将术中及术后的护理干预总结报告如下.

2001年1月至2002年10月我院应用自体外周血干细胞移植治疗恶性实体瘤11例,临床疗效满意,现将临床观察及护理体会总结如下.

自体外周血干细胞移植联合大剂量化疗是治疗恶性实体瘤、血液病的一种新技术.2000年1月至2002年10月我院共收治11例,我们对患者的心理特征进行了分析,采取相应的护理对策,取得满意效果,现报告如下.