This experiment was conducted to study the pharmacokinetics of 1florfenicol sulfonate in broiler chickens plasma.Twelve broiler chickens were used to give single intramuscular injection of florfenicol sulfonate at a dosage of 20 mg/kg.The concentrations of florfenicol sulfonate in plasma were determined by HPLC.The pharmacokinetics parameters were calculated by 3P97 computer program and fitted a one-compartment open model with weight by 1/C.The main parameters of florfenicol sulfonate in broiler chickens were as follows:T1/2 kα:(0.28±0.04)h,T1/2 Ke:(2.06±0.06)h,Cmax:(4.17±0.12)μg/mL,Tmax:(0.92±0.09)h,AUC:(16.89±0.35)μg/mL,V/F(c):(3.52±0.13)L/kg,CL/F(s):(1.19±0.03)L/(kg·h),Ke:(0.34±0.01)/h,kα:(2.57±0.37)/h,A:(6.56±0.38)μg/mL.The results showed that the distribution of florfenicol sulfonate was rapid and wide in the broiler chickens,the concentration of plasma was high and elimination was quick.

综述了氯霉素类抗菌药物氟苯尼考的药理作用、残留检测技术及水溶性氟苯尼考的研究.

病毒性呼吸道疾病系病毒感染的一类疾病,其预防与治疗是现今最难解决的问题之一.本文分别从常见的抗呼吸道疾病病毒中草药、抗呼吸道病毒中草药的主要有效成分、中草药抗呼吸道病毒感染作用机制及临床应用四个方面对当前主要抗呼吸道病毒感染的中草药进行阐述,旨在为进一步研制抗呼吸道病毒中草药奠定理论基础.

Distributed watershed hydrological model has become a focus on the research of modern hydrological model,which can effectively solve the problems such as hydrology,ecology and environment within watersheds.SWAT(Soil and Water Assessment Tool) model is an advanced,physically based,distributed hydrological model developed by USDA-ARS,which is now used worldwide for researching watershed hydrology,non-point source pollution,and management of watershed integrated with Remote Sensing(RS) and Geographic Information System(GIS).The authors describe the development of SWAT model,and sum up its primary application,improvement,existing problems and future development.SWAT model is getting widely used in China recently,and some components are modified for Chinese natural conditions.In a word,it can help you in actual research and better water conservation and management in China using SWAT model.

The paper discussed the applicability of the Reference Index-Annual Soil Loss Thickness, of the Criteria of Soil Erosion Intensity Classification based on measured bulk density, which we took Miyun Reservoir as an example. The results showed that there was an obvious difference of bulk density in different type of soils and land use. Soil loss intensity had a great error based on Reference Index of Soil Erosion Intensity Classification. Therefore, we should adopt the actual bulk density in area soil loss survey and evaluation, so as to use scientifically the Criteria of Soil Erosion Intensity Classification and offer better service to the soil loss management.