IntroductionHeat stress (HS) can progress to heat stroke, a life-threatening condition. Aquaporin-4 (AQP4) has been implicated in HS-induced brain injury, but its role in heat acclimation (HA)-mediated protection remains unclear. This study investigated whether HA ameliorates HS-induced brain damage through AQP4.Methods9L/lacZ cells were randomly assigned to four groups: Control (37 °C, 5% CO₂), HA (39 °C, 5% CO₂, 2 h/day for 6 days), HS (43 °C, 5% CO₂, 2 h), and HA+HS (HA pretreatment followed by HS). In addition, cells in the Control and HS groups were treated with the selective AQP4 inhibitor TGN-020 (0.1 μmol/mL, 2 h before HS). The expression of HSP70, HSP90, and AQP4 was measured by western blotting; AQP4 mRNA levels were assessed by RT-PCR. Cell proliferation viability was evaluated by CCK-8 assay, and apoptosis was detected by flow cytometry.ResultsNotably, AQP4 expression (RT-PCR and Western blot) was lower in the HA+HS group than in the HS group. Flow cytometry revealed that both HA+HS and TGN-020 treatment reduced apoptosis compared with HS alone.DiscussionThese findings indicate that HA attenuates HS-induced injury by downregulating AQP4 expression, and that AQP4 inhibition mimics this protective effect. AQP4 represents a potential therapeutic target for heat stroke.

OBJECTIVE:To investigate Acupuncture-herb therapy modulates gut microbiota in abdominal obesity. METHODS:A randomized controlled trial was designed in accordance with standard protocols. Abdominally obese subjects were randomized into four groups: A2 (Control): double placebo, A1 (Needle): press needle + placebo herb, A3 (herb): herbal medicine (Huatan Lishi Fang) + placebo needle, A4 (Combination): press needle + herbal medicine. After 12 weeks of treatment, groups were relabeled B1-B4. Weight, waist circumference, and body mass index were measured monthly. Gut microbiota was analyzed via 16S rRNA sequencing for diversity and abundance. RESULTS:Combined needle-herb therapy significantly reduced waist circumference (P < 0.05). All treatments altered gut microbiota composition. The combination group showed significant changes in diversity (Chao1, Shannon, Simpson; P < 0.05). Needle therapy increased Bacteroidia; herbs reduced Lachnospiraceae and Megamonas. All results were significant (P < 0.05). CONCLUSION:Combined needle-herb treatment modulated 25 key gut flora across multiple taxonomic levels in abdominal obesity. It reduced Firmicutes and Bacteroidota. Bacteroidota, Actinobacteriota, and Prevo-tellaceae may suppress obesity, whereas Proteobacteria, Lachnospiraceae, and Megamonas may promote it. The combination specifically altered Bacteroidaceae, Lachno-spiraceae, Bacteroidia, and Megamonas.

Obesity is not only a direct cause of health problems, but is also closely related to the incidence rate of a variety of noncommunicable diseases. Intervention for obesity requires high self-discipline and compliance from individuals, which often makes weight loss less smooth and prone to rebound. In this study, we prepared a dissolving microneedle (MN) loaded with compound traditional Chinese medicine (TCM). The base material was composed of a mixture of polyvinyl alcohol (PVA) and polyvinyl pyrrolidone (PVP), which met the requirements of solubility and sufficient mechanical properties. For the drug, we chose the Huatanqushi formula, which has a clear fat-reducing effect in clinical practice and is food and medicine homology. The results showed that the MN can penetrate the stratum corneum, rapidly release drugs in the dermis of the abdominal wall, alleviate the inflammatory state of local adipose tissue, regulate systemic lipid metabolism, and ultimately achieve weight loss. This MN patch is suitable for busy office workers to use conveniently, avoiding the discomfort of oral medication and the drawbacks of a large dosage and long medication time. It can effectively intervene in obesity with a minimal effect on the body.

Background: Alzheimer’s disease (AD) affects >55 million people worldwide and lacks disease-modifying therapies. Microglia, the CNS resident immune cells, dynamically transition between protective and pathological states during AD progression. Recent advances in single-cell sequencing and metabolomics reveal that microglial roles extend beyond simple M1/M2 polarization. This review synthesizes these advances into a framework integrating microglial plasticity, metabolic reprogramming, and intercellular communication in AD. Methods: We reviewed recent (2020–2026) studies on microglial biology in AD, focusing on DAM (disease-associated microglia) ontogeny, metabolic reprogramming, immune checkpoints, and glial crosstalk. Results: Microglia exhibit spatiotemporal heterogeneity, shifting from protective phagocytic phenotypes (M2, DAM1/2) in early AD to pro-inflammatory and exhausted states (M1, terminal inflammatory microglia [TIM], lipid droplet-accumulating microglia [LDAM]) as pathology advances. Key pathways—TREM2/SYK phagocytosis, Piezo1 mechanotransduction, TAM (Tyro3, Axl, Mer) receptor signaling, and metabolic regulators (HK2, iron, APOE4-driven lipid metabolism)—orchestrate these transitions. Microglia also interact with astrocytes, T cells, and peripheral immune cells via IL-3, complement C3, MHC-I and MHC-II, forming glial-immune networks that modulate Aβ clearance, tau propagation, and synaptic integrity. Conclusions: Precisely targeting microglial functional states, rather than broad immunosuppression, is a promising disease-modifying strategy for AD. Future therapies should integrate metabolic reprogramming, glial network regulation, and immune checkpoint modulation to preserve protective microglial phenotypes in early AD while suppressing pathological activation and exhaustion in advanced disease.

IntroductionIschemic stroke (IS) represents a significant global health challenge, characterized by elevated morbidity and mortality rates, largely driven by inflammatory responses. Double-negative T cells (DNTs), a distinct subset of T cells lacking both CD4 and CD8 markers, have been implicated in the pathogenesis of IS, exhibiting potentially dual roles. However, the precise functional contributions of DNTs in this context remain poorly understood.MethodsIn this study, we investigated the role of DNTs during the acute phase of IS and assessed the influence of Huang-Lian-Jie-Du Decoction (HLJD), a traditional Chinese medicinal formula, on these cells. Using single-cell transcriptomics, we identified two distinct subtypes of DNTs: an activated, cytotoxic phenotype (Kill+) and a resting, immunosuppressive phenotype (Kill-).ResultsOur findings indicate that HLJD treatment modulates the balance between these DNT subtypes, specifically reducing the proportion of cytotoxic DNTs while promoting an increase in immunosuppressive DNTs. This shift was associated with a reduction in immune cell infiltration and inflammation within the brain tissue, potentially mitigating neuronal damage.DiscussionThese results suggest that HLJD exerts neuroprotective effects in IS by modulating the activity and distribution of DNT cells, offering valuable insights into the therapeutic potential of traditional Chinese medicine for the treatment of IS. Further studies are required to elucidate the mechanisms underlying DNT-mediated immune responses in IS and to explore the broader applications of HLJD in other neuroinflammatory conditions.

OBJECTIVE:To assess the efficacy and safety of the Qingyanyin formulated granules (, QYY), press needles (PN), and their combined application in addressing abdominal obesity (AO). This trial aims to offer a more scientifically grounded therapeutic regimen for clinical interventions. METHODS:From March 2021 to July 2021, a multicenter, triple －blind, randomized 2 × 2 factorial design clinical trial was conducted across 7 centers in 4 major cities within mainland China. The trial participants were patients diagnosed with AO. The trial followed a 1∶1∶1∶1 random allocation ratio, assigning participants to one of four groups: QYY placebo plus simulated press needles (SPN) (placebo + SPN), QYY plus SPN (QYY + SPN), QYY placebo plus PN (placebo + PN), and QYY plus PN (QYY + PN). The trial participants received treatment for 12 weeks. Observe the changes in waist circumference, body weight, body mass index (BMI), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI) scores, and Pittsburgh Sleep Quality Index (PSQI) before and after treatment. RESULTS:The QYY + PN group exhibited significant improvements in waist circumference compared to placebo + PN [Difference = －1.59, 95% CI (－3.03, －0.16)] and placebo + SPN groups [Difference = －2.01, 95% CI (－3.46, －0.57)]. QYY + PN demonstrated a significant advantage over placebo + SPN [Difference = －2.01, 95% CI (－3.46, －0.57)], and no statistically significant interaction was observed between the two interventions (P > 0.05). In terms of weight and BMI improvements, the QYY + PN, QYY + SPN, and the PN + placebo groups all experienced trending greater reductions in weight compared to the placebo group. In terms of the total scores of PSQI, BAI, and BDI, all four groups exhibited improvements compared to the baseline. Specifically, concerning the change in total PSQI scores, the QYY + PN group exhibited a greater reduction; Regarding the change in total BAI scores, the PN + placebo group demonstrated a greater decrease;As for the change in total BDI scores, the QYY + SPN group displayed a greater reduction. CONCLUSION:This study confirmed that QYY + PN can effectively reduce the waist circumference of patients with AO. Furthermore, the combined approach offers greater benefits than either treatment alone, all without any reported serious adverse events.

Obesity and overweight are increasingly recognized as significant risk factors for the incidence and progression of thyroid cancer (TC). However, its epidemiological investigation including the disease burden and its trends remains insufficiently explored. This research aimed to reveal and predict the disease burden of thyroid cancer attributable to high body-mass index (TC-HBMI), which would offer significant references for focused prevention and disease management methods. The study extracted data from the Global Burden of Disease Study 2021 (GBD 2021). Deaths case, disability-adjusted life years (DALYs) case, age-standardized mortality rate (ASMR) and age-standardized DALYs rate (ASDR) were obtained from GBD 2021 to assess the global burden from 1990 to 2021. Decomposition analysis explored the driving factors to TC-HBMI. The Average Annual Percent Change (AAPC) in ASMR and ASDR of TC-HBMI was determined to analyze temporal trends by Joinpoint regression analysis. Bayesian age-period-cohort (BAPC) model was utilized to project the disease burden untill 2049. The global deaths and DALYs of TC-HBMI were 5,255 and 144,955 in 2021, exhibiting a continuous growth trend over the past 32 years. The ASMR and ASDR for males showed faster growth. The disease burden was greatest among middle-aged and older populations, while the rapidly increase in adolescents should not be overlooked. High socio-demographic index (SDI) regions and Latin America each recorded the highest disease burden within their respective categories of SDI regions and GBD regions. Additionally, Predictive models indicated a gradual upward trend from 2022 to 2049. The study revealed that the global disease burden of TC-HBMI had continuously increased from 1990 to 2021, and it was predicted to escalate until 2049. The findings emphasize the need for more detailed TC screening and weight loss measures tailored to specific regions and populations, which would benefit efforts to curb the projected rise in TC-HBMI deaths and DALYs.

Background: Thyroid cancer (TC) is the most prevalent malignant endocrine cancer, presenting a considerable challenge to global health. Obesity and overweight are significant risk factors for the onset and advancement of thyroid cancer (TC), garnering heightened interest from researchers in recent years. This research aimed to reveal and predict the disease burden of thyroid cancer attributed to high body-mass index (TC-HBMI), which would offer significant references for focused prevention and disease management methods. Methods: This research constituted an analysis of the Global Burden of Disease 2021 (GBD 2021). Deaths cases, disability-adjusted life years (DALYs) cases, age-standardized mortality rates (ASMR) and age-standardized DALYs rates (ASDR) among different sexes, age groups, SDI regions, GBD regions and countries were obtained from GBD 2021 to assess the global burden from 1990 to 2021. Decomposition analysis explored the driving factors to TC-HBMI. Trends in the deaths cases, DALY cases, ASMR and ASDR due to TC from 1990 to 2021 were assessed by Joinpoint regression analysis. Bayesian age-period-cohort model was utilized to project the disease burden till 2049. Results: In 2021, the global deaths and DALYs of TC-HBMI were 5,255 (95% UI: 3,914 to 6,653) and 144,955 (95% UI: 109,230 to 184,747), showing a notable increase compared to 1990. The Joinpoint model showed that the disease burden had continuously increased over the past 32 years, but the rate of growth had varied at different stages. The disease burden in females was higher than that in males, but the increase in disease burden for males had outpaced that of females over the past 32 years. In terms of age groups, the disease burden was higher among middle-aged and older populations and the age of onset tended to be younger. Regarding regions, the most significant growth was observed in low-middle socio-demographic index (SDI) areas, but the proportion of the disease burden from TC-HBMI among the overall TC disease burden was highest in high SDI and high-middle SDI regions. Additionally, Latin America should receive more attention for its highest disease burden among all GBD regions. Predictive models indicated that the cases of deaths and DALYs would reach an estimated 128,556 (95% CI, 39 to 26,772) and 318,523 (95% CI, 41,307.34 to 615,613.67) until 2049, showing a gradual upward trend from 2022 to 2049. Conclusion: The research revealed that the global disease burden of TC-HBMI had continuously increased from 1990 to 2021, and it was predicted to escalate until 2049. The findings emphasize the need for more detailed TC screening and weight loss measures tailored to specific regions and populations, which would benefit efforts to curb the projected rise in TC-HBMI deaths and DALYs.

IntroductionDepression, anxiety, and somatic symptoms are highly comorbid and represent the most prevalent psychosomatic health issues. Few studies have investigated the network structure of psychosomatic symptoms among traditional Chinese medicine (TCM) students. This study aims to investigate the psychosomatic health status of college students in TCM universities, while simultaneously constructing a network structure of common somatic symptoms and psychological symptoms.MethodsOnline investigation was conducted among 665 students from a university of Chinese medicine. Health Status Questionnaire, Generalized Anxiety Disorder-7 (GAD-7), and Patient Health Questionnaire-2 (PHQ-2) were used to assess the mental symptoms and physical status of participants. With the R software processing, a network model of psychosomatic symptoms was constructed. Specifically, we computed the predictability (PRE), expected influence (EI), and bridging expected influence (BEI) of each symptom. Meanwhile, the stability and accuracy of the network were evaluated using the case-deletion bootstrap method.ResultsAmong the participants, 277 (41.65%) subjects exhibited depressive symptoms, and 244 (36.69%) subjects showed symptoms of anxiety. Common somatic symptoms included fatigue, forgetfulness, sighing, thirst, and sweating. Within the psychosomatic symptoms network, “ worrying too much about things “, “uncontrollable worries” and “weakness” exhibited the high EI and PRE, suggesting they are central symptoms. “ Little interest or pleasure in doing things,” “ feeling down, depressed, or hopeless,” “ dyssomnia,” and “sighing” with high BEI values demonstrated that they are bridging symptoms in the comorbid network.ConclusionThe psychosomatic health status of college students in traditional Chinese medicine schools is concerning, showing high tendencies for depression, anxiety, and somatic symptoms. There exists a complex relationship between somatic symptoms and psychological symptoms among students. “ Worrying too much about things “, “uncontrollable worries” and “weakness” enable to serve as comorbid intervention targets for anxiety, depression, and somatic symptoms. Addressing “ little interest or pleasure in doing things,” “ feeling down, depressed, or hopeless,” “ dyssomnia,” and “sighing” may effectively prevent the mutual transmission between psychological and physical symptoms. The network model highlighting the potential targeting symptoms to intervene in the treatment of psychosomatic health.

Objective: To explore the functional mechanisms of Suanzaoren decoction (SZRD) for treating insomnia using network pharmacology and molecular docking. Methods: The active ingredients and corresponding targets of SZRD were obtained from the Traditional Chinese Medicine Systems Pharmacology database, and then, the names of the target proteins were standardized using the UniProt database. The insomnia-related targets were obtained from the GeneCards, DisGeNET, and DrugBank databases. Next, a Venn diagram comprising the drug and disease targets was created, and the intersecting targets were used to draw the active ingredient-target network diagram using Cytoscape software. Next, the STRING database was used to build a protein-protein interaction network, followed by cluster analysis using the MCODE plug-in. The Database for Annotation, Visualization, Integrated Discovery (i.e., DAVID), and the Metascape database were used for Gene Ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses. AutoDock Vina and Pymol software were used for molecular docking. Results: SZRD contained 138 active ingredients, corresponding to 239 targets. We also identified 2,062 insomnia-related targets, among which, 95 drug and disease targets intersected. The GO analysis identified 490, 62, and 114 genes related to biological processes, cellular components, and molecular functions, respectively. Lipid and atherosclerosis, chemical carcinogen-receptor activation, and neuroactive ligand-receptor interaction were the most common pathways in the KEGG analysis. Molecular docking demonstrated that the primary active components of SZRD for insomnia had good binding capabilities with the core proteins in PPI network. Conclusion: Insomnia treatment with SZRD involves multiple targets and signaling pathways, which may improve insomnia by reducing inflammation, regulating neurotransmitters.

目的:探讨中医药干预向心性(腹型)肥胖的诊断标准、干预措施、疗效评价指标、疗效评价标准的应用现状及各干预措施的效果比较.方法:检索2001-2021年中医药干预向心性肥胖的临床文献,统计分析各项干预方法、诊断标准、疗效指标及疗效标准的应用情况及干预效果.结果:最常用的干预方法为针刺疗法(68次,61.82％);最常用的诊断标准为《中国成人超重和肥胖症预防控制指南(试行)》(39篇,38.61％);常用的主要疗效指标分别是腰围(WC)(88次,87.13％)、体质量指数(BMI)(82次,81.19％)和体质量(BW)(75次,74.26％);次要指标是三酰甘油(TG)(26次,25.74％)、高密度脂蛋白(HDL)(23次,22.77％)和总胆固醇(TC)(23次,22.77％);最常用的疗效评价标准为《单纯性肥胖病的诊断与疗效评价标准》(38次,52.78％);联合疗法对向心性肥胖的改善率最高(9.72％),联合疗法中埋线+推拿对向心性肥胖的改善率最好(17.03％).结论:中医药干预向心性肥胖具有研究前景,但目前向心性肥胖的诊断标准、疗效指标及疗效标准不够统一和规范,需要进一步统一诊疗标准,为临床干预提供科学可靠的循证依据.

Introduction:Women with premenstrual syndrome (PMS) suffer heavily from emotional problems, the pathogenesis of which is believed to be related to the hypothalamic-pituitary-adrenal (HPA) axis, autonomic nervous system (ANS) and central nervous system (CNS). We took into account all 3 aspects to observed the psychological, physiological and biochemical correlations under anger and sadness in college students with and without PMS.Methods:33 students with PMS and 24 healthy students participated in the emotion induction experiment, and were required to fill out self-report scales. Their salivary cortisol (SCort), skin conductivity level (SCL), heart rate variability (HRV), blood pressure (BP) and electroencephalogram (EEG) data were collected at the resting stage and 10-15 minutes after each video.Results:Compared to healthy controls, students with PMS showed lower SCort level and higher VLF at rest, and no statistic difference in activities of ANS and HPA axis after emotional videos, but different results in EEG in all conditions. The decreases in SBP during angry video, SCort after angry and neutral videos, and increases in θ band power during sad video were moderately correlated with increases in PMS score. No intergroup differences were found in self-report emotions.Discussion:Students with PMS had lower activity of HPA axis and possibly higher activity of PNS at rest, and different response patterns in CNS in all conditions. Several EEG frequencies, especially θ band, in specific encephalic regions during emotional videos, as well as declined HPA activities in dealing with angry and neutral stressors, in which γ activity in frontal lobe may play a role, showed moderate correlations with more severe PMS.

The long-term use of antipsychotics (APs) may cause a variety of diseases, such as metabolic syndrome, antipsychotic-induced weight gain (AIWG), and even obesity. This paper reviews the various mechanisms of AIWG and obesity in detail, involving genetics, the central nervous system, the neuroendocrine system, and the gut microbiome. The common drug and non-drug therapies used in clinical practice are also introduced, providing the basis for research on the molecular mechanisms and the future selection of treatments.

名老中医传承是进一步推动中医药创新发展的关键所在,但目前名老中医研究存在重"术"轻"道"的问题,缺乏全面挖掘和传承的方法学体系及研究范式,缺乏对名老中医防治重大、难治疾病的群体研究.认为名老中医传承工作的重点应聚焦在名老中医的"道""术"研究上.通过应用扎根理论、病例系列研究、队列研究,以及数据挖掘等定性、定量混合研究方法,创新性构建了名老中医道术传承范式.提出了不同名老中医诊治重大、难治疾病的道术异同对比研究策略,为未来基于名老中医群体开展重大、难治疾病诊疗方案提供参考意见.并利用表述性状态传递(REST)互联网架构提供网络化开放式的稳定服务,搭建医疗、科研、传承、推广一体化的服务平台作为推广范式,进一步推广名老中医道术研究成果,惠及基层医生、科研人员和广大群众.

OBJECTIVE: To systematically review and analyze the effect of acupuncture and acupoint catgut embedding in treatment of abdominal obesity to provide a more reasonable clinical treatment regimen.METHODS: Ten databases were searched as of August 2022: the English databases PubMed, Embase, Cochrane Library, Web of Science, Wiley, and Scopus and the Chinese databases China National Knowledge Infrastructure Database, China Science and Technology Journal Database, Wanfang, and SinoMed/Chinese Biomedical Literature Database. Randomized controlled trials (RCTs) of acupuncture and acupoint catgut embedding as the main interventions to treat abdominal obesity were extracted. The investigators imported the citations into EndNote version X9.1 for deduplication, screening, extraction, and integration. The risk of bias in the included RCTs was assessed according to the Cochrane Handbook. RevMan 5.4 software was used to conduct a Meta-analysis of RCTs that met the inclusion criteria.RESULTS: Thirteen RCTs (1069 patients) were included in this study, and the data of eleven RCTs (966 patients)were include in the Meta-analysis. The results showed that acupoint catgut embedding can significantly change the weight and waist circumference of patients with abdominal obesity when compared to sham acupuncture or no treatment [mean difference (MD) = 2.32, 95% confidence interval (CI) (1.88, 2.76), P < 0.000 01], [MD = 3.47, 95% CI (1.99, 4.94), P < 0.000 01]. The change in hip circumference after acupuncture was also significant [MD = 0.89, 95% CI (0.12, 1.66), P = 0.02].CONCLUSION: This study found that acupuncture and acupoint catgut embedding can effectively treat abdominal obesity, therefore, these interventions can be used as clinical supplements and alternative therapies. The diagnostic criteria of the existing studies and the intervention measures of the control group are not unified. It will be necessary to improve the clinical study protocols and expand the sample size to further validate the reliability of the results obtained of this study.

目的 初步探索腹型肥胖者的证候要素分布规律,为其临床干预提供辨证论治依据.方法 多中心协作招募腹型肥胖者539例,采用"中医证候要素辨识问卷"进行临床症状及一般信息的采集,将所收集的症候学资料及一般信息建立数据库,运用SPSS统计学软件做因子分析,提取证候要素,并统计证候要素分布特点.结果 临床症状中出现频率位于前5位的依次为精神紧张(80.71％)、神疲(79.04％)、小便色黄(73.84％)、情绪低沉(67.53％)、大便黏滞(66.98％).经因子分析后共得到病性类证候要素9个,以气虚最多见(24.49％),其次为阳虚(14.66％)、痰(13.36％)、气滞(11.87％)、火(热)(11.50％)、湿(6.31％)、风(6.12％)、血虚(6.12％)、阴虚(5.57％).得出病位类证候要素9个,最主要的有4个,分别是肝(37.66％)、脾(23.56％)、胃(14.47％)、肾(14.10％).结论 腹型肥胖的证候以气虚、阳虚为本,以痰实为标,主要病位为肝、脾、胃、肾.

思想政治教育与专业课程教学的全面深入融合,是构建全员全程全方位育人格局的重要途径.基于OBE(outcome-based education)理念,结合中医诊断学的课程特点及内容,课程组深入挖掘课程思政元素,凝练课程思政内涵,并通过教学实践,不断完善中医诊断学课程的思政建设,逐步建立了中医诊断学实训课程思政的教育模式.为增强学生的职业使命感,提升学生的医学人文素养奠定基础,以达到全面育人的目的.

Lung cancer is a malignant tumor with the highest incidence and mortality in China, which seriously affects the quality of life of patients. Traditional Chinese medicine (TCM) plays a unique advantage in the treatment and rehabilitation of lung cancer. In order to standardize TCM diagnosis and treatment and disease management of clinical medical workers, the Chinese Association of Integrative Medicine issued the “Expert Consensus on the Diagnosis and Treatment of Lung Cancer by Integrated Traditional Chinese and Western Medicine” in August 2021. Experts' recommendations were made on the clinical staging and syndrome differentiation and classification of lung cancer, characteristic TCM therapies, and nursing care of integrated traditional Chinese and Western medicine. This article interpreted the Consensus on the above aspects from a nursing perspective, hoping to provide references for clinical medical workers in the treatment and nursing care of lung cancer.

中医面诊作为望诊中较易获取且包含信息最多的诊断方法,从古至今一直是众多学者关注与研究的对象.本文通过对古代面诊内容的梳理总结,从面部皮肤颜色、形态、皮损分布的角度展开详述,为面诊在现代临床中的广泛应用提供了理论与发展基础.在此背景下,文章探讨了借助现代技术进行的各类面诊仪器研发成为面诊走向现代化的未来发展趋势.