Objective To carry out targeted prevention and treatment by studying on the prevention and control of brucellosis information Chifeng City in 2008. Method The information of brucellosis prevention and control was collected and trends and influencing factors analyses were conducted. Results 5360 blood samples were collected,1136 cases of patients were reported,of which the positive rate was 21.19%. Conclusions Movement of livestock without quarantine and immunization,livestock management methods,industrial structure adjustment and poor awareness of personal protective brucellos are the major factors of brucellosis outbreak.The comprehensive brucellosis prevention and control measures are still carried out currently and adopting new measures to control the epidemicin new suitation.