Objective To explore the curative effect and mechanism of pantoprazole combined with re-bamipide in chronic erosive gastritis. Methods This study included 150 patients with chronic erosive gastritis who were randomly divided into two groups. The control group received pantoprazole treatment, while the ob-servation group received pantoprazole combined with rebamipide treatment. The difference of clinical symp-toms and gastric mucosal histology related factors before and after the treatment between two groups were an-alyzed. Results Before treatment, there was no statistically significant difference between two groups of stom-ach pain, abdominal distension, acid regurgitation and acid reflux symptom scores (P>0.05). However, the score of observation group was significantly lower than control group after 30 days of treatment (P<0.05). Af-ter treatment, endoscopic disappearance rate of tissue edema, congestion, erosion in observation group was sig-nificantly higher than the control group (P<0.05). In addition, there was no statistical difference of mononu-clear cell infiltration grade, neutrophil infiltration grade and prostaglandin E2 (PGE2) between the two groups before treatment (P>0.05). But after treatment, the mononuclear and neutrophil cell infiltration grade of ob-servation group was markedly lower than control group (P<0.05), and PGE2 was higher than control group (P<0.05), with statistical significant difference, which showed the remission of clinical symptoms might associ-ated with the histology factors. Conclusion Combined pantoprazole and rebamipide effectively improved not only the patients′clinical symptoms, but also the inflammatory factors related to gastric mucosa histology.
目的了解综合医院急诊观察病人的总体情况及其特点,为合理安排急诊卫生资源提供参考依据。方法对2004~2005年我院急诊留观病例就病种构成、年龄、性别等进行统计分析。结果本组疾病构成中前5种疾病依次为心血管疾病513例(26.15%),呼吸系统465例(23.70%),消化系统297例(15.14%),脑血管病181例(9.25%),内分泌代谢系统79例(4.00%)。疾病年龄构成中>70岁比例较高(32.42%)。结论该组资料与全国城市统计资料基本相似。提示急诊工作重点宜放在心、脑血管疾病、老年病及多发病的救治上。
咳嗽变异型哮喘,又称隐匿性哮喘,是指以慢性咳嗽为唯一临床表现的哮喘特殊类型[1].因其缺乏喘息、胸闷、呼吸困难等典型哮喘的症状和体征,易与其他疾病相混淆,为进一步了解其临床特点,减少误诊,现特总结1998年4月-2003年10月的64例报告如下:
肺功能是老年尘肺患者健康监护的一项重要内容,是评价老年尘肺患者临床治疗效果和生存质量的主要指标.为了掌握这一特殊群体的肺功能特征,2003-04-2003-08月对广元市60岁以上尘肺患者的肺功能情况进行了抽样调查.
对2001年1月至2003年1月内广元市人民医院急诊内科急危重症抢救病例进行临床总结以了解综合医院急诊抢救患者的总体情况及特点,为提高急诊医疗质量,为急诊科医护人员的配备和培养指明方向,同时为合理使用现有急诊资源提供参考依据.