目的 研究当归四逆汤联合中药足浴治疗糖尿病周围神经病变的临床效果.方法 选取我科在2017年1月--2018年6月收治的88例患者,采用随机数字表法分为两组,参照组(n=44)予以常规疗法,实验组(n=44)在此基础上予以当归四逆汤联合中药足浴治疗,对比二组的治疗总有效率及相关指标.结果 实验组的治疗总有效率为97.73％,明显高于参照组的81.82％,实验组的腓总神经、胫神经传导速度均优于参照组,组间对比P＜0.05.结论 应用当归四逆汤联合中药足浴治疗糖尿病周围神经病变效果理想,对促进神经传导、改善血液流变指标具有重要帮助,值得推广..

目的 (1)研究0.5%耐乐平连续腰麻用于糖尿病患者下肢手术的安全性和有效性;(2)研究血糖水平对麻醉临床效果的影响。方法 (1)选择糖尿病下肢手术患者60例,随机分为2组。比较2组患者痛觉阻滞程度、最高阻滞平面,运动阻滞程度;(2)观察不同血糖水平对麻醉临床效果的影响。结果 (1)2组患者均可达到完善的镇痛效果,但耐乐平的镇痛起效时间、运动阻滞起效时间、最大运动阻滞时间均比布比卡因显着延长(P<0.05);(2)术前血糖水平<7.8mmol/L麻醉效果最佳,术前血糖水平>11.2mmol/L麻醉效果不佳,有统计学意义(P<0.05)。结论 (1)小剂量0.5%耐乐平连续腰麻用于糖尿病患者下肢手术具有麻醉效果确切,在临床上安全可行;(2)适宜血糖水平麻醉效果好。

Objective: To study and investigate the safety and effectiveness of different ways of anesthesia on the diabetes patients undergoing surgery.Methods: A total of 262 cases of surgical patients with diabetes were selected.Among the patients,146 cases were per-formed waist and epidural anesthesia and 116 cases,general anesthesia.Results: The perioperative blood sugar level and mean insulin doses were less in combined spinal and epidural anesthesia group than in general anesthesia group,with statistical significance(P0.05).In com-bined spinal and epidural anesthesia group,the increased extent of fasting and postprandial blood glucose,glycated hemoglobin levels were less than those in general anesthesia group(P0.05).Through Logistic regression analysis,factors such as age,smoking,drinking and body mass index,except for gender,were highly correlated with the anesthesia effect on diabetes patients(positive).Conclusion: Waist and epidural anesthesia is better for patients with diabetes.

目的 观察三联疗法针灸治疗糖尿病胃轻瘫的临床疗效.方法 将66例糖尿病胃轻瘫患者随机分为2组,对照组34例采用西医常规治疗;治疗组32例在对照组治疗基础上加用三联疗法针对糖尿病胃轻瘫患者病情分层次予以治疗的一种方法,同时配合针灸.2组均周后观察疗效.结果 显效率和总有效率治疗组分别为77%和91%,对照组分别为48%和76%,2组比较均有显著性差异(P均<0.05).结论 三联疗法加针灸治疗糖尿病胃轻瘫疗效显著.

Compared with bacterial symbionts, little is known about archaea in sponges especially about their spatial distribution and abundance. Understanding the distribution and abundance of ammonia-oxidizing archaea will help greatly in elucidating the potential function of symbionts in nitrogen cycling in sponges. In this study, gene libraries of 16S rRNA gene and ammonia monooxygenase subunit A (amoA) genes and quantitative real-time PCR were used to study the spatial distribution and abundance of archaea in the South China Sea sponge Holoxea sp. As a result, Holoxea sp. specific AOA, mainly group C1a (marine group I: Crenarchaeota) were identified. The presence of ammonia-oxidizing crenarchaea was observed for the first time within sponge cells. This study suggested a close relationship between sponge host and its archaeal symbionts as well as the archaeal potential contribution to sponge host in the ammonia-oxidizing process of nitrification.

目的 研究小剂量0.5%耐乐平连续腰麻用于糖尿病患者下肢手术的安全性和有效性.方法 择期糖尿病下肢手术患者30例,随机分为两组.两组分别分次小剂量注入0.5%耐乐平(R组)0.5ml或0.5%布比卡因(B组)0.5ml,比较两组患者痛觉阻滞程度、最高阻滞平面,运动阻滞程度.结果 两组患者均可达到完善的镇痛效果,但耐乐平的镇痛起效时间、运动阻滞起效时间、最大运动阻滞时间均比布比卡因显著延长(P<0.05);而痛觉恢复时间、运动恢复时间比布比卡因显著缩短(P<0.05).结论 小剂量0.5%耐乐平连续腰麻用于糖尿病患者下肢手术具有麻醉效果确切,并能达到完善的镇痛效果,不良反应少,在临床上安全可行.

Objective To determine the molding of Dandengtongnao drop pill.Methods The craft was molded with crosscut experiment,and the kinds of ground sustance,condensate,best ratio of ground substance and Abstract,drop temperature,consendate temperature,drop distance and speed were considered as affectors.Results The craft condition was PEG 4000 and powder of Dandengtongnao as 4∶1,mixed completely,heated to melted and kept in 80℃.the materials was dripped from 2.2 mm/2.4 mm with constant speed of 40 drop/min to liquid paraffin.Conclusion The experimental result might supply the experimental data to determine the molding of Dandentangnao drop pill.

Objective To establish high performance liquid chromatography(HPLC) and assay hesperidin content of Huoxiangzhengqi capsule.Methods To use the way of HAPC.Chromato bar is octadecylsilane chemically bonded silica as bulking agent(DiamosilTM,5.0 μm,200 mm×4.6 mm),Mobile phase is methanol-0.5% acetic acid solution(30:70),Detected wave length is 284nm,Flow rate is 1.0 mL/min.Results Hesperidin has satisfactory linear correlation between 5.592～74.56μg/mL.Regression Equation is A=21 168.38C-8 066.67,R=0.999 99.Coefficient of recovery is 99.32%.

目的:研制出三七分散片,并考察其人参皂莓类饷体外溶出度。方法:以CMS-Na为崩解剂,采用内外加入法,以淀粉作出粘合剂,并通过正交试验法优选出三七分散片的最佳工艺处方。结果:按照优选出的工艺处方制得的三七分散片能在3分钟内完全崩解,且均匀性实验能通过20目筛,同时溶出度也明显优于三七片。结论:处方合理,工艺可行,制成的分散片符合质量标准要求。

扁平苔藓(Lichen Planus, OLP)是一种原因不明的慢性或亚急性炎症性皮肤病.皮损常为紫红色多角形扁平丘疹,常有口腔黏膜损害[1].我们收集了2004-11～2008-04门诊病例中经病理证实的50例扁平苔藓,进行临床和病理分析.

目的：以盐酸小檗碱为例，比较滴定法和薄层色谱法。方法：采用滴定法和薄层色谱法测定盐酸小檗碱的含量。结论：薄层色谱法较滴定法更为准确、简便。

目的：建立一种新的薄层方法鉴别强力枇杷露。方法：采用TLC法检验罂粟壳。结果：分离效果良好。结论：本方法合理，简便，能较原鉴别方法更好地控制该药的质量，反映该品种的内在质量。