>患者男,60岁,1周前因"不能进食,自行采用自制铁质扩张条插入食管后出现咳嗽、咳痰、呼吸困难"收治入院。患者2年前因发现食管癌(病理证实为鳞癌Ⅲ级)曾在我院胸外科行食管癌根治术,术后2个月因吻合口狭窄在我院行探条扩张术,此后2个月因吻合口狭窄放置6 cm食管内支架(支架位于距门齿19～25 cm处),再此后3个月因肿瘤复发堵塞食管支架上口再次置入4 cm支架(支架位于距门齿17～21 cm处),入院前1年因肿瘤再次堵塞颈段食管支架
目的探讨术中光动力治疗口腔癌的治疗效果。方法应用德国产光敏剂photcsan-32mg/kg,静注后48小时,在全麻下行常规手术切除肿瘤后,用德国产CERALASPDT630Laser200J/cm照射术野和肿瘤组织边缘。结果6例患者近期疗效良好。结论在手术切除的基础上,进行PDT治疗,消灭术野基底和边缘的微小病灶,降低局部复发率。对口腔癌的治疗具有较好的临床应用价值。
目的探讨激光动力学治疗(PDT)早期喉癌的治疗效果.方法应用德国产光敏剂photosan-3,2mg/kg静脉注射后48h用德国产CERALAS PDT630 Lasser200J/cm照射病变部位,必要时72～96h内再重复1～2次.结果10例患者近期疗效良好.结论PDT治疗早期喉癌具有疗效确切,副作用小,可重复治疗的特点,对早期喉癌的患者具有较好的临床应用价值.
Objective To explore the cli nical therapeutic effectiveness of photodynamic the rapy (PDT) in treating bronchial lung carcinoma.Method The lesion site was irr adiated with German CERALAS PDT 630 Laser 200 J/cm 48 hours after intraveno us dr ip of the German photosensitizer photosan-3. Repetition was done within 72-96 ho urs if necessary.Results Twenty-three patie nts received the PDT treatment and the early e ffect is satisfactory.Eleven cases showed CR with disappearance of the tumor and unobstructed bronchus.Nine cases showed SR and 6 cases had little remainder of the tumor which was equivalent to half of the original size.Two cases showed MR resulting from that the optical fiber could not be inserted because of the obstruction by the tumor.One case with metastasis to tracheal prominence died of heavy bleeding 3 days after PDT tre atment. ConclusionS Treating bronchial lung carcinoma with P DT has the advantage of definite efficacy and few side effects,and the treatment can be repeated. It is of clinical app licable significance and suitable for patients with central-type lung cancer of inoperable trachea, bronchi or postoperative residual relapse or for patients with chemotherapy and radiotherapy contraindications
目的探讨激光动力学治疗(PDT)支气管肺癌的适应症,治疗方法与效果.方法应用德国产photosan-3 2mg/kg静注后48h用德国产CERALAS PDT 630 Laser 200j/cm照射病变部位.必要时72～96h内再重复1～2次.结果治疗14例病人近期疗效好.结论 PDT治疗支气管肺癌具有疗效确切、副作用小、可重复治疗的特点,特别适用气管、支气管腔内生长为主的中央型肺癌、支气管肺癌术后残端复发及年老体迈、有手术、放化疗禁忌症的病人.
目的:探讨激光动力学治疗(PDT)临床应用的方法与效果.方法:应用加拿大产光敏剂photofrin或德国产photosan-3 2mg/kg静注后48h用英国产DIOMED 630 PDT Laser 300j/cm照射病变部位.必要时72h内再重复1次.结果:治疗15例病人近期疗效好.结论:PDT治疗食道癌具有疗效确切、副作用小、可重复治疗的特点,特别适用年老体迈及有手术、放化疗禁忌症的病人.
