经直肠超声引导下经会阴活检是目前诊断前列腺癌(PCA)的主要方法.近年来随着前列腺癌的发病率及检出率的不断提高,此项技术也日益受到学者们的重视.我院2002年1月至2009年6月对临床疑为前列腺癌的患者89例进行经直肠超声引导下前列腺穿刺活检术并明确诊断,效果较好,现报告如下.
外科手术中由于局部病变引起的泌尿器官解剖位置变异、解剖层次欠清晰,或术者对泌尿器官正常解剖位置、寻找标记不够明确,盲目操作等易造成损伤.我院自1985～2002年治疗12例由外科手术引起的泌尿系统损伤病人,现报道如下.
1990年1月至2002年12月,我院共收治膀胱腺癌患者28例,除去6例转移性膀胱腺癌,其余22例为膀胱腺癌,现将诊治体会报告如下.
Purpose and Methods:The expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 were s tudied by SP immunohistochemistry in 68 cases of transitional cell carcinoma of bladder to investigate the relationship of the expression and clinicopathologica l parameters.Results:The expression of MMP-9 and TIMP-1 were higher in TCCB.The expression rate of MMP-9 was 60% and was elevated with grade and stage.The expre ssion rate of TIMP-1 was 45.5%.There was a inverse relationship between the expr ession rate and grade or stage.It was found that the tumors expressed MMP-9(+)/T IMP-1(-) had higher pathological stage and grade than the groups expressed MMP-9 (-)/TIMP-1(+).Conclusions:The expressions of MMP-9 and TIMP-1 be correlated with grade and stage of TCCB.The increased MMP-9 expression and decreased TIMP-1 exp ression were associated with the invasion and development of TCCB.
