1例多发性骨髓瘤IgG-KAP型合并无症状性高磷血症,患者血清钙水平正常,甲状旁腺功能正常,无外源性磷摄入史,排除肾功能不全、甲状旁腺功能减退、过多磷摄入所致的高磷血症.本病例提示:在临床工作中遇到不明原因的高磷血症患者,应考虑到多发性骨髓瘤的可能,后者的血磷升高有可能是假性,因此不需要磷酸盐结合剂治疗.

Objective:To analyze the risk factors for acute cerebral infarct progression in posterior circulation(ACIPPC)and predicting function of plasma MMP-9.Methods:In this study we focused on ACIPPC and compared factors between ACIPPC and N-ACIPPC by single factor analysis,and sieved the independent risk factors for ACIPPC by logistic(Forward:Wald)analysis and demonstrated the predicting role of plasma MMP-9 to the infarction volume of ACIPPC by linear correlation and regression analysis.Results:Single factor analysis showed that hypertension history,diabetes mellitus history,dysphagia,neurological severity,blood glucose and plasma MMP-9 were significantlt different between ACIPPC and N-ACIPPC(P0.05).Logistic regression analysis indicated that blood glucose,neurological severity and plasma MMP-9 were independent risk factors for ACIPPC.Linear correlation and regression analysis manifested that plasma MMP-9 was a predicting factor for the DWI volume of ACIPPC patients.Conclusion:ACIPPC results from multi-factors,while blood glucose,neurological severity and plasma MMP-9 are independent risk factors for ACIPPC,and plasma MMP-9 may be a predicting factor for the brain stroke volume of DWI in ACIPPC patients.

Cushing's病是因垂体分泌过量促肾上腺皮质激素(ACTH)引起.Cushing's病约占库兴氏综合征患者总数的65%～75%,发病年龄以25～45岁为多见.70%～80%为垂体腺瘤,微腺瘤最多见.

在我国,原发性肾小球疾病是引起慢性肾功能衰竭最主要的原因,对其诊断主要依靠肾脏病理性活检.但肾活检是一种有创伤的检查方法,且需要较高的技术和设备,因此,不同程度地制约了其在基层的广泛开展.

近年研究提示,血管内皮生长因子(vascular endothelial growth factor,VEGF)是一种促进血管内皮生长及渗透的分子,能促进内皮细胞的增生、迁移,增强内皮细胞的通透性,并参与了微血管病变的病理过程.在肾脏组织中VEGF的浓度和分布变化与肾脏疾病患者的蛋白尿产生密切相关,同时组织中的VEGF含量与肾脏病变程度相关.本文就此进行摘要综述.

临床所用多种药物对肝功能均有损害,其中抗生素及抗肿瘤药物的肝损害尤为突出,在白血病的治疗过程中,不可避免地要使用多种抗生素和抗肿瘤药物,因此,白血病患者发生药物性肝损害几率较高.

格林-巴利综合征(GBS)患者应用皮质类固醇治疗早在50年代即已开始。近10余年来，国内外应用大剂量甲基强的松龙冲击疗法治疗GBS，效果颇佳。我院自1996年来用此疗法进行……

脑卒中是中老年人的常见病、多发病,其发病率、致残率很高,卒中后不少患者继发癫痫.为了探讨脑卒中后癫痫的临床特征及预后,本文对我院1995年1月至2001年12月收治的997例脑卒中后继发癫痫的55例患者作一临床分析.

患者,男,34岁.因双下肢无力3月,加重20d于2001年10月入院.患者于入院前3个月出现双下肢无力、僵硬,行走不稳,伴全身乏力厌油,近20天出现渐进性行走困难就诊.无肢体疼痛、麻木,无发热、头昏、头痛.病后大小便正常,体重无下降.