Objective To explore the relationship between serum ferritin(SF) and nonalcoholic fatty liver diease(NAFLD),and to provide clinical basis for earlier diagnosis and treatment in patients with NAFLD.Methods SF level were measured in 256 cases NAFLD patients diagnosed by ultrasonography and in 100 normal subjects(normal control group) by using radioimmunoassy.Results SF levels in patient with NAFLD was significantly higher than in normal control group(P 0.01).Conclusion SF level increased in patients with NAFLD,indicating that SF are related to NAFLD.The measurement of SF may be helpful in stimation of the diagnosis,treatment and prognosis of NAFLD.

目的探讨道路交通伤致重型颅脑损伤的特点并总结相应的救治措施。方法分析2006年1月—2010年10月收治的32例重型颅脑交通伤病例的临床资料、救治方法及结果。结果 32例患者中,单纯颅脑损伤13例,多发伤19例。原发性昏迷25例,继发性昏迷4例。GCS评分3～5分10例,5～8分22例。保守治疗17例,开颅手术12例,其他手术3例。恢复良好15例,中残3例,重残1例,植物生存2例,死亡11例,病死率为34.4%。结论重型颅脑交通伤伤情重、多发伤多、伤情复杂,及时有效的院前急救及入院后处理对患者的预后有重要意义。

高原地区气候特点(如低氧压,缺氧,高辐射及高寒等)与平原明显不同.长期以来,急性高原反应一直是人类移居高原的不利因素,尤其是军队进驻高原的一大障碍.预防与控制急性高原反应是高原医学研究的重要课题.

Objective To investigate the effect and mechanism of astragalus injection on renal ischemia-reperfusion injury in rat. Methods Rat models of renal ischemia-reperfusion were established,and 25 male rats were randomly divided into 3 groups,treatment group with astragalus injection(n=10),renal ischemia-reperfusion injury model group(n=15) and sham operation group(n=5)as the control.Astragalus injection(4 mL·kg~(-1))was given intravenously during clamping renal artery in treatment group and one half of the dose was infused after opening the clamp during reperfusion.In model group equal amount of 0.9% sodium chloride solution was given.In the sham operation group(control group),the rats were anesthetized with laparotomy but without blocking renal blood flow.The P-selectin and ICAM-1 expression,malonyldialdehyde(MDA) contents and super oxide dismutase(SOD) activities in renal tissues,level of serum blood urea nitrogen(BUN) and creatinine(Cr)were detected. Results After renal ischemia reperfusion injury,there were significantly up-regulated expressions of P-selectin and ICAM-1,with increased MDA content and declined SOD activity in renal tissue,and significant increase in BUN and Cr content in model group,and in treatment group with astragalus injection these effects were significantly depressed as compared with model group. Conclusion It is thought that the adhesion molecules P-selectin and ICAM-1 take part in the process of renal ischemia-reperfusion injury,and astragalus injection significantly reduce the reaction of lipid peroxidation with a protective effect on renal ischemia-reperfusion injury.