Objective:To identify and analyze the differential expression of L-lactate dehydrogenase B chain(LDH-B)in the penis of rat offspring after maternal exposure to di-n-butyl phthalate (DBP). Methods:Twenty pregnant rats were randomly divided into two groups and given DBP by gastric intubation at the dose of 800 mg / kg per day in the experimental group or 5 ml per day soybean oil in the control group from the 14 th to 18 th day of pregnancy. Penises were harvested from the fetal rats of the normal and exposed groups respectively at GD l9 .The expression of LDH-B detected and analyzed by Western blot and immunohistochemistry. Results: LDH-B expressed both in the experiment group and the control group,but the expression level is much lower in the experimental group than in the control group(P 0.05). LDH-B was mainly located in the cytoplasm of the penis’s tissue. Conclusion:LDH-B protein expressed much lower in the penis of the rat offspring after maternal exposure to DBP than in the penis of the rat offspring without exposure to DBP.

睾丸表皮样囊肿是比较少见的睾丸良性肿瘤.1998年3月～2009年7月,我院共收治本病患者7例.现报告如下. 临床资料:本组7例患者的年龄为20～43岁,病程5个月～2 a.均以阴囊内偶发肿块就诊,其中1例偶伴轻微睾丸疼痛不适,无阴囊坠胀等不适.均为单侧发病,其中左侧2例,右侧5例.体检:睾丸表面可触及质地较硬的肿物,表面较光滑,略凸向睾丸表面,对侧睾丸无异常,除1例有轻微触痛外其他均无触痛.肿瘤直径0.6～3.1 cm.