Objective: To observe the intervention effects of TCM and herbs for the patients with DNA ploidy anomaly. Methods: All 338 patients were randomized into two groups according to clinical manifestations, the pa-tients with DNA ploidy anomaly but showing no clinical manifestations were chosen as the control group, and the patients showing different clinical manifestations as herbal intervention group, the patients in herbal intervention group accepted placing herbs in the vagina since the first day when the period ended, two herbal preparations in the vagina each night, 14 days were one course of the treatment, the interval was 16 days, the second courses of the treatment started, the therapy paused for one month each three courses of the treatment, the improvements of the pa-tients with DNA ploidy anomaly in both groups were observed and followed up at the fourth month, eighth, 12th and 18th month. Result: Cure rate of DNA ploidy anomaly is positively related to intervention measures and intervention time.

目的 了解白银市0～3岁婴幼儿微量元素缺乏状况,并观察小儿肠胃康颗粒辅助治疗微量元素缺乏的疗效.方法 采用原子吸收光谱法,对白银市妇幼保健院儿保门诊3 308名0～3岁儿童进行头发微量元素测定及结果分析,对微量元素缺乏的患儿在补充缺乏元素的基础上加服小儿肠胃康颗粒.结果 0～1岁组儿童中钙缺乏最高(63.11％),其次为铁缺乏(25.73％)、锌缺乏(9.70％)、镁缺乏(0.80％)、铜缺乏(0.58％).1+ ～3岁组中,微量元素缺乏依次为钙(48.00％)、锌(33.50％)、铁(13.50％)、铜(3.50％)、镁(1.50％).2组钙、锌、铁及铜缺乏比较,差异有统计意义(P＜0.05);镁缺乏2组差异无统计意义(P＞0.05).对照组总有效率为90.2％,治疗组为97.5％,经统计学分析,差异有统计意义(P＜0.05).结论 0～3岁婴幼儿微量元素钙、锌、铁缺乏较普遍;在补充微量元素的基础上加用小儿肠胃康颗粒可增加疗效,显著改善症状,促进食欲,缩短疗程.

目的通过对门诊妇科体检妇女进行宫颈新柏氏液基细胞学检测(TCT)及DNA定量细胞学检测,提高宫颈病变检出率,降低漏诊率,对降低宫颈癌死亡率具有重要意义。方法液基制片两张,一张进行TCT诊断,一张通过全自动扫描系统进行细胞DNA定量分析,对两种检查结果阳性的患者,阴道镜下取宫颈活检确诊。结果 3 000例妇女经宫颈标本TCT及DNA细胞学检测,妇科疾病患病率为63.00%。查出DNA倍体异常者594例,异常率19.80%;TCT异常者205例,异常率6.83%。选取317例DNA异常者或TCT异常者阴道镜下取活检送病理诊断,确诊慢性宫颈炎37例,不典型鳞状细胞(AUSCUS)28例,宫颈上皮内瘤变(CIN)1级148例,CIN 2级59例,CIN3级24例,宫颈癌21例。结论 DNA定量细胞学检测阳性率远高于TCT;两者联合检测,能提高宫颈病变阳性的检出率,有助于对宫颈癌及其癌变早期诊断,杜绝了宫颈病变的发生与发展,为重点人群及早管理提供了机会。

目的 了解白银市儿童发铅水平与钙、锌关系,为合理补充微量元素提供资料.方法 采用原子吸收光谱法对门诊体检的1 000名1～14岁以童头发进行微量元素测定.结果 1～14岁儿童铅中毒率、缺锌率随着年龄增长而降低,缺钙率随着年龄增长而增加.结论 多数儿童有钙、锌缺乏现象,铅中毒儿童更多.应定期对儿童进行微量元素检测,加大防铅宣传,合理补充微量元素.

目的:了解白银市区儿童发铅含量与微量元素的关系,为合理补充微量元素提供指导.方法:采用原子吸收光谱仪对400名14岁以下儿童头发进行微量元素测定.结果:铅含量超标82例,缺钙占第1位,缺锌占第2位,缺铁占第3位,缺铜占第4位.结论:多数儿童都有微量元素缺乏的现象,铅中毒的儿童更为明显.建议每年检查微量元素,在医师指导下合理补充微量元素.

目的:探讨儿童发铅含量与智商的关系.方法:选择白银市400名6～12岁儿童用韦氏儿童智力量表测定智商,用原子吸收法测定发铅含量.结果:发铅含量与智商有相关性(r=-0.538,P＜0.01).结论:智商越高发铅含量越低,发铅与智商呈负相关.