目的 探讨胸腺活化调节趋化因子(TARC)在血液透析皮肤瘙痒患者中的意义.方法 选择维持性血液透析患者24例,并随机分为2组,对照组继续原来透析方案,实验组应该更高级别透析器联合血液灌流治疗,并共同治疗20周,并同时选12例健康体检者设为健康组,采用酶联免疫吸附试验ELISA法检测血清TARC水平,并比较TARC水平及变化情况.结果 血液透析患者组TARC水平显著高于健康组,经20周治疗后,实验组TARC明显低于对照组,并均有统计学意义(P<0.05).而实验组中重度皮肤瘙痒人数下降到6人,较对照组明显改善(P<0.05).结论 血清TARC水平与血液透析患者皮肤瘙痒程度相关,高通量透析联合血液灌流可改善患者皮肤瘙痒.

目的:探讨女性抗缪勒氏激素(AMH)水平与多囊卵巢综合征(PCOS)各临床表型相关性及其妊娠结局预测.方法:选取我院妇产科经达英-35促排卵助孕的PCOS患者85例,依照鹿特丹标准将其分为四个临床表型组,并比较四组病例AMH水平差异及其经口服短效避孕药炔雌醇醋酸环丙孕酮(达英-35)促进排卵治疗后妊娠结局指标与AMH相关性.结果:AMH在不同临床表型PCOS中水平由低到高:无多囊型<非高雄型<月经规律型<经典型.口服短效避孕药达英-35结局比较:A组AMH与获卵数、临床妊娠率呈正相关性(P<0.05);B组AMH与获卵数、临床妊娠率均无相关性(P>0.05);C组AMH与获卵数呈正相关性,与临床妊娠率无相关性(P>0.05);D组AMH与获卵数、临床妊娠率均无相关性(P>0.05).结论:AMH表现:经典型>月经规律型>非高雄型>无多囊型,在不同临床表型PCOS中水平呈现出由高到低形态;在对AMH的影响中,稀发排卵和(或)无排卵(OA)对AMH无明显影响,多囊样改变(PCO)则强于T;非高雄型临床表现最轻微,经典型PCOS妊娠结局最差.AMH在非高雄型和无多囊型中预测价值不大,但在经典型及月经规律型PCOS中有预测价值.

Mycoplasma pneumonia is one of the common pathogens that lead to respiratory tract infection.With the time passing by,the incidence of mycoplasma pneumoniae infection increased rapidly.Mycoplasma pneumoniae is a kind of prokaryotes that located in the middle of viruses and bacteria with the transmissive route of respiratory droplets and aerosols.The symptoms of the disease were as follows: upper respiratory tract infection,pharyngitis,bronchitis,pneumonia with severe pulmonary complications,such as immune hemolytic anemia,meningoencephalitis,myocarditis,pericarditis,nephritis,or even death.With the hush infection,mycoplasma pneumoniae was highly occurred on the areas that children and family yarded,and the disease was difficult to heal.Early diagnosis of mycoplasma pneumonia becomes more and more important with the advantages of decreasing the incidence of complications and preventing the spread of mycoplasma pneumonia.In this paper,we aimed to reviewing and summing up the recent development of the diseases.

目的对所选样本同时进行丙肝病毒核心抗原和抗体的ELISA检测,揭示此两种方法联合应用在丙肝诊断与治疗中的应用价值。方法从临床申请丙肝病毒RNAPCR法检测的临床标本中选取1298份标本(其中阳性结果191例,阴性结果1107例),同时进行丙肝病毒核心抗原和抗体的ELISA检测。结果丙肝病毒核心抗原和抗体的ELISA检测都阳性,该标本数为60例,同时丙肝病毒RNAPCR法检测亦为阳性,阳性率100%,而传统单一丙肝病毒抗体的ELISA检测法,假阴性率为2.33%(3/129);丙肝病毒核心抗原和抗体的ELISA检测都阴性,该标本数为1101例,仅有2例丙肝病毒RNAPCR法检测为阳性,假阴性率只占0.18%,而传统单一丙肝病毒抗体的ELISA检测法,假阴性率为1.56%(2/128);丙肝病毒核心抗原ELISA检测结果阳性而抗体ELISA检测结果阴时,假阴性率为37.5(3/8),若同时应用此种结果可提示进一步申请丙肝病毒RNAPCR法检测从而大大降低假阴性率。结论对临床样本同时进行丙肝病毒核心抗原和抗体的ELISA检测,能够明显提高丙肝诊断符合率,同时降低假阴性率。