目的:探讨阿莫西林、雷贝拉唑联合克拉霉素治疗Hp相关性消化性溃疡的疗效及对患者生活质量的影响,为临床治疗提供依据.方法:选择2013年4月-2015年4月本院收治的Hp相关消化性溃疡患者120例,根据治疗方法不同将患者分为研究组和对照组,每组各60例.研究组采用阿莫西林、雷贝拉唑及克拉霉素联合治疗,对照组采用奥美拉唑单药治疗.观察并比较两组患者的临床疗效、SDS评分及SAS评分.结果:研究组总有效率显著高于对照组,差异有统计学意义(P＜0.05);研究组SDS、SAS评分低于对照组,差异有统计学意义(P＜0.05).结论:采用阿莫西林、雷贝拉唑和克拉霉素联合治疗Hp相关消化性溃疡具有较好的临床疗效,能够显著改善患者的临床症状,提高生活质量,值得推广应用.

Objective To explore the value of somatostatin in the treatment of hepatic hydrothorax. Methods 54 patients with hepatic hydrothorax were randomly divided into two groups: somatostatin treatment group and control group. All the clinical features were summarized. The difference was compared between two groups including the clinical efficacy,the reduction of hydrothorax and side effects. Results The male was easier to appear hepatic hydrothorax.The liver cirrhosis after HBV was the main pathogen and the dominant place happened in the right thorax. The total effective rate in the treatment group was much higher than that in the control group( 86. 2% vs 68. 0%),which had statistical difference( P < 0. 05). Meanwhile,the total rate of side effects in the treatment group was much lower than that in the control group( 34. 5% vs 60. 0%),which had statistical difference( P < 0. 05). And electrolyte disturbance was the main side effect. Conclusion Somatostatin can effectively treat the hepatic hydrothorax and decrease the incidence of side effects.

Experimental Study has been conducted to investigate the impacts on the growth of Chlorella vulgaris from, phosphorus and nitrogen respectively. Specially, the Kse and KSN , which represent growth effects from phosphorus and nitrogen, were obtained by using the Monod Equation based on experimental results. The study suggests that impacts from TP overtake that from TN, with KSN 〉Ksp. While the level of Chlorella vulgaris peaks when the ratio of N/P reach 60.

目的探讨抑癌基因PTEN和血管内皮生长因子（VEGF）蛋白在大肠癌中表达的意义。方法采用免疫组化SP法检测48例大肠癌中PTEN和VEGF蛋白的表达,并分析其与临床和病理特点的关系。结果大肠癌中PTEN蛋白表达阳性率为45.8%（22/48）,显著低于正常大肠黏膜组织的阳性率（P＜0.01）;VEGF蛋白表达阳性率为72.9%（35/48）,显著高于正常大肠黏膜组织的阳性率（P＜0.01）;PTEN和VEGF蛋白表达呈负相关（P＜0.01）;PTEN蛋白低表达和VEGF蛋白高表达与大肠癌Dukes分期、浆膜浸润、淋巴结转移有关（均P＜0.01）,而与年龄和组织学类型无关（P＞0.05）。结论PTEN和VEGF蛋白表达与大肠癌临床病理特征和生物学行为有密切关系,联合检测PTEN和VEGF蛋白的表达,对大肠癌的恶性程度及预后判断具有重要的临床意义。

Objective:To explore the diagnosis and treatment of recurrent primary retroperitoneal tumor (PRT ).Methods: Clinical data of 33 cases of recurrent PRT since 1992 was analyzed retrospectively .Results:19 cases in those 33 recurrent PRT were re-operated, and lengthen the survival time or relieve the symptom.Conclusion:To prevent recurrent of PRT, the key is periodic follow-up after first operation, early detect the recurrent, enough preoperative preparation and correct evaluation of organ involved.

[目的]分析广东省潮汕地区南澳岛1995～2003年恶性肿瘤发病状况及其变化趋势和居民饮食习惯特点.[方法]根据南澳岛肿瘤发病登记系统的资料,收集核实数据,建立数据库,计算肿瘤粗发病率、标化发病率,并分析肿瘤性别分布.用SPSS 10.0作统计处理,应用x2检验作时间趋势分析.另外,通过问卷调查,了解南澳岛土著居民(678名)和梅州客家人群(435名)的饮食和生活习惯,并且委托中国疾病控制中心检测了两地人群毛发样本(随机抽取南澳岛居民93名,梅州客家对照人群25名)22种微量元素含量(ICP法).[结果]1995～2003年,南澳岛恶性肿瘤发病1 286例,其中男性874例,女性412例,年平均粗发病率为203.11/10万.主要恶性肿瘤粗发病率顺序为(1/10万):食管癌(71.07),贲门癌(34.59),肝癌(26.38),肺癌(24.95),胃癌(16.90),鼻咽癌(4.74),乳腺癌(3.79),大肠癌(2.68),膀胱癌(2.05),胰腺癌(1.74).在此9年间,恶性肿瘤发病率表现出上升趋势,其中以肝癌、肺癌、鼻咽癌、乳腺癌、大肠癌发病率上升比较显著;食管癌、贲门癌发病率仍处于高发状态,食管癌发病450人,贲门癌219人,两者合计占恶性肿瘤发病总人数的52.02%,居首位.南澳人群中平均每月烟、酒消耗量均大于梅州客家人群,同时毛发中铜(Cu)、镁(Mg)、钠(Na)、锌(Zn)、钾(K)、铅(Pb)、锶(Sr)、钴(Co)、铬(Cr)、镍(Ni)、汞(Hg)等微量元素含量也明显高于梅州客家人群.[结论]1995～2003年南澳岛恶性肿瘤仍呈高发状态,表明在南澳岛可能存在较稳定的致癌因素,生活及环境因素可能对肿瘤发病有一定影响.