目的:探讨辅助生殖技术助孕患者心理疲乏感来源及针对性护理干预措施.方法:将2018-01月至2020-01月期间,在我院接受辅助生殖技术助孕的患者作为研究对象,共计100例,按照不同的护理干预模式将所有研究对象分为对照组(n=50)与观察组(n=50),对照组实施常规护理,观察组根据患者的心理疲惫感来源,实施针对性护理.比较两组患者干预前后心理疲乏感程度以及护理满意度.结果:两组干预前心理疲乏程度评分无明显差异(P＞0.05),干预后观察组明显高于对照组(P＜0.05);对照组护理满意度为76.00％,观察组为92.00％,观察组明显高于对照组(p＜0.05).结论:根据辅助生殖技术助孕患者的心理疲惫感来源,实施针对性护理干预措施,能有效的减轻患者的心理疲乏感,改善其不良情绪,有助于提升护理质量,从而提高护理满意度,值得应用.

【Objective】 To examine the influence of body mass index(BMI)on IVF pregnancy outcome in polycystic ovary syndrome(PCOS)patients.【Methods】 A retrospective cohort study was conducted using existing data on 224 PCOS patients who received IVF-ET treatment using standard long protocol at the third affiliated hospital of Zhengzhou University from Jan 2009 to Dec 2011.All patients were divided into 2groups as BMI under or over 24 kg/m2,Obesity group(BMI ≥24.0)64 cases,Control group(24.0> BMI >18.5)160 cases.the differences of pregnancy outcomes between obesity and control PCOS patients were compared.【Results】BMI and Basic testosterone(T)in obesity group were higher than that in control group(P <0.05).There were no significant difference in the number of retrived oocytes,dose of Gn,Gn duration,fertilization rate between the two groups(P >0.05);There were no significant difference in clinical pregnancy rate and abortion rate between the two groups(P >0.05),Obesity PCOS patients have higher risk of developing gestational diabetes(GDM)than control group(P <0.05).【Conclusion】 Obesity PCOS Patients were increased risk of hyperandrogenism and pregnancy complications GDM impact in pregnancy outcome.

Objective To investigate the influence of high body mass index(BMI)on in vitro fertilization and embryo transfer(IVF-ET)pregnancy outcome in the patients with polycystic ovary syndrome(PCOS).Methods A retrospective cohort study was conducted using existing data on 224PCOS patients with IVF-ET by the standard long protocol in this hospital from Jan 2009to Dec 2011.All patients were divided into 2groups according to BMI,the high BMI group(BMI≥24.0,64 cases)and the normal BMI group(18.5≤BMI<24.0,160cases).The differences of pregnaney outcomes between the high BMI and normal BMI PCOS patients were compared.Results 1.Basic testosterone(T)in the high BMI group was higher than that in the normal BMI group(P<0.05).2.There were no statistical difference in the number of retrived oocytes,dose of Gn,Gn duration,fertilization rate between the two groups(P>0.05);the high BMI group demonstrated the higher endometrial thickness and lower good quality embryo rate than the normal BMI group(P<0.05).3.There were no statistical difference in the clinical pregnancy rate and the abortion rate between the two groups(P>0.05),the high BMI group had the higher risk of developing gestational diabetes(GDM)than the normal BMI group(P<0.05).Conclusion PCOS patient with high BMI is liable to develop hyperandrogenism and increases the occurrence rate of pregnancy complication gestational diabetes mellitus(GDM),but without affecting the clinical pregnancy rate.

近年来,由于环境污染、饮食、工作压力及其他因素的影响,使不孕不育患者持续上升.男性因不可逆的无精子症、先天性无精症和染色体异常导致的不育症,而女方至少有一侧输卵管通畅.供精人工授精是可以解决其不孕难题的办法之一. 1 资料与方法 1.1 资料 2011年1月至2011年6月在郑州大学第三附属医院生殖医学中心就诊的249例不育患者.

目的:评价体外受精-胚胎移植(IVF-ET)超促排卵周期中卵泡晚期增加人绝经期促性腺激素(HMG)用量,同时补充重组人黄体生成素(r-hLH),对主要实验室指标和临床妊娠结局的影响.方法:选择行IVF-ET或卵胞浆内单精子显微注射(ICSI)技术助孕治疗的患者212例,采用标准长方案垂体降调节,根据超促排卵的卵泡晚期血清黄体生成素(LH)水平将所有病例分为两组:血清LH水平持续较低补充r-hLH者72例设为实验组(r-hLH组),血清LH水平持续正常未补充r-hLH者140例设为对照组(非r-hLH组),比较两组患者的年龄、基础内分泌状态、促性腺激素(Gn)使用时间及使用量、人绒毛膜促性腺激素(HCG)注射日各项内分泌激素值、获卵数、两组不同助孕方式的双原核(2PN)受精率、优质胚胎率、移植周期的着床率及临床妊娠率.结果:两组患者的年龄、基础LH、基础卵泡刺激素(FSH)、基础雌二醇(E2)水平、超促排卵天数、Gn总量、IVF/ ICSI助孕的2PN受精率、移植周期的着床率、临床妊娠率差异均无统计学意义(P＞0.05).r-hLH组超促排卵FSH总量低于非r-hLH组,差异有统计学意义(P＜0.05)；r-hLH组HMG总量高于非r-hLH组,差异有统计学意义(P ＜0.05)；HCG注射日r-hLH组血清LH水平低于非r-hLH组,差异有统计学意义(P＜0.05)；r-hLH组的优质胚胎率高于非r-hLH组,差异有统计学意义(P＜0.05).结论:激动剂标准长方案超促排卵周期卵泡晚期血清LH水平持续较低者增加HMG的用量,适量补充r-hLH可提升卵子成熟度,显著提高优质胚胎率,一定程度改善IVF/ICSI的助孕结局.