目的:运用品管圈管理工具,减少门诊不合理处方,提高门诊处方质量.方法:资料来源于2020年1—10月重庆市巴南区人民医院门诊处方共714458张,其中不合理处方5482张.在门诊药房开展品管圈活动,筛选出活动前5个月(2020年1—5月)门诊不合理处方进行现状调查、原因分析、制定解决问题的对策并组织实施,对比分析开展品管圈活动前后门诊不合理处方数的变化情况.结果:开展品管圈活动后5个月(2020年6—10月),门诊不合理处方发生率由开展品管圈活动前5个月(2020年1—5月)的28.42张/d降至8.13张/d,降低幅度为71.39％,不合理处方数显著减少.结论:运用品管圈管理方法能有效降低门诊处方的不合理率,促进医院合理用药,保障患者用药安全.

目的 探讨不同时间静脉注射托烷司琼治疗乳腺癌化学治疗(简称化疗)所致恶心呕吐的临床疗效.方法 选取医院2016年8月至2018年10月收治的乳腺癌患者96例,按乱数表法分为研究组和对照组,各48例.两组患者化疗药物为顺铂(60 mg/m2)+多柔比星(50 mg/m2)+氟尿嘧啶(500 mg/m2),研究组和对照组患者分别于化疗开始前和化疗结束后静脉注射枸橼酸托烷司琼注射液.结果 研究组总有效率显著高于对照组,24 h内恶心、呕吐次数显著少于对照组,补液时长显著短于对照组,生活质量评分显著高于对照组(P<0.05);研究组与对照组患者不良反应发生率相当(8.33％比14.58％,χ2=0.924,P=0.336>0.05).结论 乳腺癌患者化疗前预防性静脉注射托烷司琼能有效控制化疗所致恶心呕吐症状,提高患者生活质量.

Objectives: to further understand the type of unreasonable prescriptions in the outpatient and emergency department of our hospital, to improve the quality of prescriptions, to improve the rationality of prescriptions, and to embody the importance of intervention prescriptions from the window pharmacist. Methods: retrospective analysis of intervention prescriptions in the outpatient and emergency department of our hospital from June 2010 to May 2012. Results: a total of 13689 intervention prescriptions, in which there were 10411 intervention prescriptions revised by pharmacy, and irrational prescriptions were reduced from 13689 down to 3278. Conclusions: irrational prescriptions in the outpatient and emergency department of our hospital were obviously decreased by the intervention of pharmacy, the quality prescription rate was evidently increased. Intervention prescriptions from pharmacy provides an support for rational prescriptions in the outpatient and emergency department.