Purpose:To investigate the protective effects of burdock concentrate on concanavalin A(ConA)-induced liver injury in mice.Methods:Mice liver injury model was induced by ConA vena caudalis injection.Liver,thymus and spleen index,contents of ALT,AST in serum and TNF-α,NO in liver were measured.Liver histopathological changes were examined accordingly.Results:Compared with modal group,the liver index was decreased and thymus index was increased in PA(peel of burdock extrated by ethanol)group(p0.05).The contents of ALT,AST in serum,and TNF-α,NO in liver homogenate were significantly decreased(p0.01).A significant improvement was also observed in pathohistology examination.MW(peeled root extrated by water)had no effect on biochemical indicators and liver histological morphology in mice.Conclusion:PA has protective effect on ConA-induced liver injury in mice.This maybe implementated by inhibiting T lymphocyte activity and decreasing the release of inflammatory factors.

On the basis of analyzing the characteristics of the media corporations,this paper focuses on discussing three strategies adopted in the developmental process of the media corporations:differentiation strategy,diversification strategy,coopetition strategy.At the same time,in order to ensure the successful implementation of development strategies,media corporations should make efforts to set up learning-type dynamic network-based organizations,build a reasonable structure of personnel quality,and shape excellent corporate cultures and leadership role,etc.

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