目的:建立测定盐酸决奈达隆片含量及有关物质的方法。方法:采用高效液相色谱法。色谱柱为C18,以甲醇-乙腈-磷酸盐缓冲溶液（32∶50∶18）为流动相,流速为1.5 ml/min,检测波长为220 nm,柱温为40℃。结果:决奈达隆与各杂质分离度良好,盐酸决奈达隆检测质量浓度线性范围为5.2~103.0μg/m（lr=0.999 9）,低、中、高质量浓度回收率分别为100.4%、100.6%、100.2%,平均回收率为100.4%,RSD=0.8%（n=3）;杂质A、杂质B、主成分、杂质C、杂质D的检测限分别是0.25、0.25、0.5、1.0、1.0 ng。结论:建立的方法专属性好、操作简便,可用于盐酸决奈达隆片含量及其有关物质的测定。

The polymethacrylic and polyacrylamide inverse opal photonic crystals films (PMAM) have been prepared by using the sintered silica photonic templates, during which the photonic templates are infiltrated by the precursor solutions with the methacrylic and the acrylamide bi-functional monomer, and then polymerized under the UV light (365 nm) and in the end the polymerized films are immersed in HF solutions for the remove of templates. By the analysis of UV/Vis spectra, with the pH increasing, their UV/Vis spectrum peaks are red-shifted at pH=4.0~7.0. But they have no response to the ionic strength, so they can provide the potential matrix membrane for preparing the pH sensors, metal ions and small biomolecules imprinted photonic crystal sensors.