[Objective] To determine the impact of transcatheter arterial chemoembolization(TACE) in primary hepatocellular carcinoma(PHC) by comparing the syndromes.[Method] From March 2005 to December 2008,274 PHC patients who were hospitalized in the Traditional Chinese Medicine Department of Changhai Hospital and who had only undergone TACE were included.Syndromes of the patients were judged and collected before and after the treatment.With portal vein tumor thrombus(PVTT) or not,the patients were grouped and their data were analyzed again.[Result] Data of the 274 patients demonstrated that,among all the simple syndromes,level of Qi Deficiency increased after TACE,and momentum showed level of Blood Stasis was decreasing while that of Dampness Syndrome was rising;as to complex syndromes,level of Liver Qi Stagnation increased,level of Liver Blood Stasis had the rising trend while that of Dampness Heat Syndromes had the decreasing trend.The aggravating of Dampness Syndrome and Spleen and Kidney Yang Deficiency was severer in patients with PVTT than in those without.Profiles of the patients underwent TACE for the first time revealed that scores of Qi Stagnation,Excessive Heat,Liver Qi Stagnation Syndrome and Spleen Qi Deficiency Syndrome decreased after the treatment.[Conclusion] Impact of TACE on syndrome gave the evidence of local improvement and general impairment in patients with PHC.

[目的]初步探讨经动脉化疗栓塞(TACE)治疗对肝癌患者证候的影响.[方法]收集2005年3月至2008年12月长海医院中医科收治的274例次仅行TACE治疗的肝癌患者,采用配对检验等统计学方法对患者治疗前后证候的变化进行统计分析,并将有无癌栓作为分组因素,对患者TACE治疗前后证候的变化进行对比分析.[结果]274例次肝癌患者行肝脏TACE术后基本证候中气虚证程度加重(P＜0.05),血瘀证有减轻趋势,水湿证有加重趋势；复合证候中肝气郁结证程度减轻(P＜0.05),肝血瘀阻证有减轻趋势,湿热内蕴证有加重趋势.有癌栓者治疗后水湿证及脾肾阳虚证加重程度较无癌栓者大(P＜0 05).[结论]TACE治疗对证候的影响体现了肿瘤病情的好转及机能的损耗.