目的 分析2014-2021年湖北省输入性卵形疟病例的流行病学特征,为消除疟疾后的风险评估提供科学依据.方法 根据国家传染病报告信息管理系统收集2014-2021年湖北省卵形疟病例资料,对病例的地区、时间和人群分布,感染来源地及就诊情况等建立数据库,并进行统计分析.结果 2014-2021年,湖北省共网报输入性疟疾病例840例,其中输入性卵形疟病例115例占13.96％(115/840).全省报告卵形疟病例居前5的地市依次为武汉市33例、宜昌市16例、黄石市13例、襄阳市11例和黄冈市7例.12月报告的病例数最多为17例占14.78％(17/115),7月报告的病例数最少为4例占3.48％(4/115).98.26％(113/115)的输入性卵形疟病例来自非洲22个国家,主要来自刚果金(19例)、尼日利亚(12例)和安哥拉(9例)这3个国家.病例初诊单位主要集中在地市级医疗机构占35.65％(35/115),初诊诊断为疟疾的病例82例,初诊正确率为71.30％(82/115).全省45.22％的卵形疟病例由地市级医疗机构确诊.结论 湖北省2014-2021年均有输入性卵形疟病例报告,感染来源主要来自非洲.病例的初诊和确诊单位主要集中在县级及以上医疗机构.因此,需要持续提升医疗机构的疟疾防治意识和检测能力,特别是针对卵形疟原虫,巩固全省消除疟疾成果.

目的 了解湖北省临床治愈类晚期血吸虫病人基本情况,为晚期血吸虫病救治管理提供科学依据.方法 根据《晚期血吸虫病诊断标准》和《晚期血吸虫病临床治愈标准》筛查出湖北省临床治愈类晚期血吸虫病人,收集整理病人基本情况、救治情况及现状,采用描述性分析方法进行统计分析.结果 共收集整理临床治愈类晚期血吸虫病人3 258例,其中男2 059例(63.20％),女1 199例(36.80％),平均年龄(63.40±12.41)岁,63.38％的病例分布在荆州.临床分型以腹水型患者为主,共2 231例(68.48％),巨脾型967例(29.68％).确诊病例610例(18.72％),临床诊断病例2 648例(81.28％);行脾脏切除术者有485例(14.89％),有211例曾有消化道出血史(6.48％),平均内科救治次数(4.03±3.05)次,外科救治次数(1.61±1.46)次.结论 湖北省晚期血吸虫病免费救治工作效果显著,对临床治愈类晚期血吸虫病人加强监测和随访管理尤为必要.

目的 湖北省省级疟疾诊断参比实验室对各级疟疾实验室上送的输入性疟疾病例留存血样进行复核,并对诊断和复核结果进行分析,评估全省各级疟疾实验室的检测能力.方法 收集中国疾病预防控制信息系统中2016-2020年湖北省报告的输入性疟疾病例诊断单位、诊断结果和留存样品,对诊断单位进行描述性分析,并由省级疟疾诊断参比实验室对疟疾病例样品采用血涂片镜检和巢式PCR进行复核,比较各级疟疾实验室诊断结果与省级疟疾诊断参比实验室复核结果的阳性和虫种符合情况,分析不同疟原虫虫种诊断符合情况,应用SPSS 17.0软件进行统计学分析.结果 2016-2020年湖北省共报告疟疾病例608例,疟疾病例诊断单位医疗机构占89.5％ (544/608),疾病预防控制中心占10.5％ (64/608),其中地市级医疗机构诊断病例占54.6％ (332/608).2016-2020年医疗机构占疟疾病例诊断单位的比例分别为84.1％ (132/157)、84.4％ (92/109)、90.4％ (122/135)、95.2％ (157/165)和97.6％ (41/42) (x2=16.815,P＜ 0.05).省级疟疾诊断参比实验室共复核604例留存样品,其中92.4％ (558/604)的病例被各级疟疾实验室确诊为疟疾,88.5％ (494/558)感染虫种判定正确.不同年份疟疾病例诊断疟原虫阳性符合率为82.9％ (34/41) ～96.2％ (151/157)、虫种符合率为79.4％ (77/97) ～94.4％ (118/125),差异均有统计学意义(x2=9.273、13.787,P＜0.05).医疗机构的诊断疟原虫阳性符合率(93.2％,503/540)和虫种符合率(89.5％,450/503)均高于疾病预防控制中心的(85.9％,55/64)和(80.0％,44/55),省、市、县、乡级医疗机构诊断疟原虫阳性符合率分别为100％ (74/74)、93.3％ (308/330)、90.2％ (110/122)、和11/14,虫种符合率分别为100％ (74/74)、88.3％ (272/308)、86.4％ (95/110)、9/11,呈现级别越高诊断正确率越高的趋势(x2=13.092、15.598,P＜0.05).恶性疟原虫、间日疟原虫、三日疟原虫、卵形疟原虫、混合感染诊断虫种符合率分别为96.9％ (373/385)、96.0％ (72/75)、10/16、48.8％ (39/80)和0,差异有统计学意义(x2=132.880,P＜0.05).结论 湖北省疟疾病例的诊断单位主要是医疗机构,各级疟疾实验室检测能力总体较高,对非恶性疟原虫的虫种鉴别能力有待提高.

目的 了解2016-2020年湖北省疟疾疫情流行特征,为优化消除疟疾后的防控策略提供科学支撑.方法 通过国家传染病报告信息管理系统收集2016-2020年湖北省网报疟疾病例资料,对病例感染虫种、感染来源地、三间分布和就诊情况等进行分析.不同医疗机构间的初诊确诊率的比较采用x2检验.结果 湖北省2016-2020年共报告疟疾病例560例,全部为境外输入性疟疾病例.其中,恶性疟387例 (占69.11％)、间日疟75例 (占13.39％)、卵形疟80例(占14.29％)、三日疟16例(占2.86％)、混合感染2例(占0.36％).2016-2020年,报告疟疾病例数分别为151、96、127、151和35例,其中2020年报告疟疾病例数较2019年下降76.82％.所有疟疾病例感染地来自4个洲的39个国家,其中输入病例数居前5位的国家分别是刚果(金)(117例)、尼日利亚(49例)、埃塞俄比亚(48例)、安哥拉(45例)和刚果(布) (32例).2016-2020年各月均有疟疾病例报告,其中1、2和11月为病例报告的高峰月,报告病例数分别为77、76和51例.湖北省除神农架林区外,16个市(州)均有疟疾病例报告,主要分布在武汉(184例)、宜昌(81例)、黄石(56例)、襄阳(39例)和十堰(36例).病例以20～49岁年龄组居多,占85.36％ (478/560).男性病例540例,女性20例,男女性别比为27∶1.报告疟疾病例中,361例(占64.47％)在发病后2d内就诊,69例(占12.32％)在发病11d后就诊.396例初诊诊断为疟疾,初诊确诊率为70.71％.病例初诊主要集中在县级以上医疗机构(73.21％,410/560),县级以上医疗机构初诊确诊率为77.32％ (317/410);在乡(镇)卫生院、个体医生和村卫生室初诊的分别为45例、16例和27例,初诊确诊率分别为40.00％ (18/45)、1/16和11.11％ (3/27),不同医疗机构间的初诊确诊率差异有统计学意义(x2=103.744,P＜0.05).24 h内确诊的病例占55.89％ (313/560),初诊至确诊时间间隔≥4d的占26.43％ (148/560).疟疾病例主要由医疗机构确诊,占80.89％ (453/560).2016-2020年,湖北省报告2例输入性恶性疟死亡病例.结论 2016-2020年,湖北省报告疟疾病例均为输入性疟疾病例,以恶性疟为主,武汉、20～49年龄组、男性人群为主要分布.病例主要在医疗机构就诊,县级及以上医疗机构初诊确诊率较高.

目的 分析2014-2018年湖北省疟疾诊断参比实验室样本检测结果,为巩固湖北省疟疾诊断水平提供科学依据.方法 收集湖北省2014-2018年疟疾网报病例诊断结果和样本,由省级疟疾诊断参比实验室通过镜检和巢式PCR对每份样本进行检测,分析不同年份和不同地区网报阳性结果和虫种符合情况,分析省级镜检和巢式PCR结果.结果 2014-2018年湖北省共网报疟疾病例674例,省级疟疾诊断参比实验室复核672例,确定疟疾病例633例.总体阳性符合率为94.20％,各年和各地、市(州)阳性符合率均高于80.00％,不同地、市(州)间的阳性符合率差异有统计学意义(x2= 42.49,P＜0.001).总体虫种符合率为89.73％,不同年份和不同地、市(州)间虫种符合率差异均有统计学意义(均有P＜0.001).省级疟疾诊断参比实验室镜检与巢式PCR结果一致率为88.89％,两种方法检测结果一致率在不同虫种间的差异有统计学意义(x2 =57.37,P＜0.001).结论 湖北省2014-2018年疟疾网报病例诊断质量总体较高,对非恶性疟原虫的虫种鉴别能力有待提高.

目的 评价湖北省级疟疾参比实验室应用万孚疟原虫检测试剂盒(RDTs)诊断输入性疟疾的效果.方法 收集2015年1月至2018年6月湖北省网报疟疾病例和阴性删卡病例的完整血标本,进行回顾性分析,以省级疟疾参比实验室确诊结果 为标准,分别与RDTs检测结果 、镜检检测结果 和巢式PCR检测结果 进行比较分析.结果 省级疟疾参比实验室共收集完整血标本440份,确诊阳性疟疾病例418例,阴性病例22例.在恶性疟原虫的鉴定能力上,RDTs最佳,符合率为100.00％;巢式PCR次之,符合率为97.49％;镜检法的符合率为91.40％.对于其他3种疟原虫(间日疟原虫、卵形疟原虫和三日疟原虫)的种特异性鉴定能力,RDTs为最低,巢式PCR为最优,镜检法次之.根据12项单因素指标的综合分析,RDTs得分为32分,综合推广率最高,镜检法和巢式PCR得分分别为24分和19分.结论 RDTs在疟疾检测中具有一定优势,但对虫种的特异性鉴定能力较低,可以作为镜检法的辅助工具,在湖北省消除疟疾后的监测工作中广泛推广应用.

目的 了解湖北省人体重点寄生虫病流行现状及影响因素.方法 按照《全国人体重点寄生虫病现状调查实施细则》的要求,调查采用分层正群抽样方法,在2014-2015年选取15个县36个点农村人群开展土源性线虫病、带绦虫病、和肠道原虫调查,每个点调查250人,共调查9 718人;选取8个县10个点城镇人群开展华支睾吸虫病调查,每个点调查250人,共调查2 770人.采用改良加藤厚涂片法(Kato-Katz法)检查肠道蠕虫卵、带绦虫卵、华支睾吸虫卵,生理盐水和碘液直接涂片法查肠道原虫滋养体和包囊,对3～6岁儿童加做透明胶纸肛拭法检查蛲虫卵.结果 湖北省农村人群肠道寄生虫总感染率为1.57％,共检出肠道寄生虫8种,分别为肠道线虫4种,吸虫1种,绦虫1种,肠道原虫2种,蛲虫的感染率最高(2.55％);全省4个生态区中湘赣丘陵山地生态区肠道寄生虫感染率最高3.06％;不同年龄组间感染率差异有统计学意义(P＜0.01),60～69岁年龄组感染率最高(2.25％),且以钩虫为主.不同性别人群肠道寄生虫感染率差异有统计学意义(P＜0.01),女性高于男性.本次调查共涉及到14个职业,仅4个职业人群发现有土源性线虫感染,不同职业间肠道寄生虫感染率差异有统计学意义(P＜0.01),其中农民的感染率最高为1.59％.结论 湖北省第3次的寄生虫病调查结果显示湖北省农村人群肠道寄生虫病感染率及肠道原虫感染率与湖北省第2次寄生虫病调查结果相比呈明显下降趋势.但农村老年人、女性、学生和学龄前儿童感染率仍然相对较高,需加强这类人群的寄生虫防治健康教育.儿童的蛲虫感染应成为今后寄生虫病防治重点.防治重点地区为农村,重点人群是小学生、学龄前儿童和文化程度低以及年龄大的农民.

目的 评价疟疾参比实验室应用巢式PCR技术诊断输入性三日疟的效果.方法 采用巢式PCR对2015-2017年湖北省网报疟疾病例和疑似病例血标本进行疟原虫核酸检测,筛查三日疟阳性标本,并与疟疾快速诊断试剂盒(RDTs)检测结果、吉氏染色显微镜镜检诊断结果进行比较.结果 367例网报输入性疟疾病例中,经巢式PCR共检出15例(4.1％)三日疟病例.在这15例三日疟病例中,省级疟疾参比实验室镜检13例诊断为三日疟,1例为间日疟,1例为卵形疟;市级疾病预防控制中心镜检7例为三日疟,8例为间日疟;RDTs方法阳性6例;阴性9例.结论 在输入性三日疟的诊断和分型上,巢式PCR明显优于RDTs和镜检法,RDTs不能取代镜检对罕见疟疾进行诊断.

目的 了解湖北省并殖吸虫病的流行现状.方法 选取湖北省兴山县、恩施市、郧西县、保康县、南漳县、随县、竹山县、巴东县8个县(市)作为监测点,开展主动监测.包括采集溪蟹检测囊蚴感染情况,采用酶联免疫吸附试验(ELISA)检测人群血清并殖吸虫特异性抗体IgG和IgM.结果 2012-2017年在8个监测点共调查3 561人,总体阳性率1.42％(52/3 651),男性阳性率1.22％(21/1 716),女性阳性率1.68％(31/1 845),差异无统计学意义(x2=1.287,P＞0.05),其中兴山县4次调查共1 128人,阳性率2.57％(29/1 128);共调查溪蟹760只,平均重量9.81 g,阳性率25.00％(190/760),感染度7.15个/只,其中兴山县共调查340只,阳性率27.94％(95/340).结论 湖北省并殖吸虫病的传播流行风险依然存在,应持续开展监测防控和健康教育宣传,以免出现暴发流行.

BACKGROUND:Hubei Province, China, has been operating a malaria elimination programme. This study aimed at investigating the epidemiologic characteristics of malaria in Hubei Province (2005-2016) to plan resource allocation for malaria elimination.METHODS:Data on all malaria cases from 2005 to 2016 in all counties of Hubei Province were extracted from a web-based reporting system. The numbers of indigenous and imported cases during the disease control (2005-2010) and elimination (2011-2016) stages, as well as their spatiotemporal distribution, were compared.RESULTS:A total of 8109 malaria cases were reported from 2005 to 2016 (7270 and 839 cases during the control and elimination stages, respectively). Between 2005 and 2010, indigenous malaria cases comprised the majority of total cases (7114/7270; 97.9%), and Plasmodium vivax malaria cases accounted for most malaria cases (5572/7270; 76.6%). No indigenous malaria cases have been reported in Hubei Province since 2013. Imported malaria cases showed a gradually increasing trend from 2011 to 2016, Plasmodium falciparum was the predominant species in these cases, and the number of counties with imported cases increased from 4 in 2005 to 47 in 2016. During the control and elimination stages, the most likely spatial clusters for indigenous cases included 13 and 11 counties, respectively. However, the cluster of indigenous malaria cases has not been identified since September 2011. For imported cases, the most likely cluster and three secondary clusters during both stages were identified.CONCLUSIONS:Hubei Province has made significant achievements in controlling and eliminating malaria; however, the region now faces some challenges associated with the increasing number and distribution of imported malaria cases. Priorities for malaria elimination should include better management of imported malaria cases, prevention of secondary malaria transmission, and ensuring the sustainability of malaria surveillance.

Hubei Province was an unstable malaria transmission area,and was one of the provinces in our country with severe malaria epidemic in the history.After several decades' prevention and control to malaria,the malaria prevalence has been effectively controlled in Hubei.In 2010,Malaria Elimination Action Plan (2010-2020) was initiated in Hubei.Between 2010 and 2016,2 135 067 fever patients received blood smear tests,and all the cases were reported to network within 24 hours.Since 2012,all the cases have been laboratory-confirmed,epidemiological investigated within 3 days,and the foci disposed within 7 days,so as to effectively prevent the occurrence of secondary cases.A total of 82 485 person-times (including malaria control personnel,clinicians and microscopic inspectors) were trained,the province has made use of various ways to carry out malaria health education activities,distributed a total of 4 185 906 health education materials.The Mid-term assessment proves that malaria elimination has made a great process in Hubei Province,no indigenous malaria cases were reported in this province since 2013.The assessment of malaria elimination was successfully completed in 95 counties and 14 cities.Hubei Province faces new challenges,such as an increase in the number of imported malaria cases.The priorities for malaria elimination should include better management of imported malaria cases and ensuring the sustainability of malaria surveillance in order to further consolidate the achievements of malaria elimination.

目的 湖北省级疟疾参比实验室对各市(州)级疟疾实验室所送血涂片和滤纸血进行复核检测,评估全省各市(州)级疟疾实验室的检测能力.方法 湖北省级疟疾参比实验室收集2015-2017年全省疟疾病例和疑似疟疾病例样品,采用镜检法和巢氏PCR进行复核检测,以省级疟疾参比实验室确诊结果为标准,对市(州)级输入性疟疾实验室检测能力进行评估.结果 2015-2017年,全省16个市(州)送检相对完整样本400份,其中武汉市送样量最多(占32.50％).省级疟疾参比实验室对400份样品进行复核检测,确诊疟疾阳性样品374份,阴性样品26份.16个市(州)级疟疾实验室检测完成率均为100％,将市(州)级各虫种鉴定和阴性检测结果占比与省级疟疾参比实验室确诊结果占比进行对比分析,武汉市、鄂州市和天门市鉴定结果符合率为100％,其他13个市(州)级疟疾实验室鉴定结果占比与省级确诊结果占比相比均有不一致情况,主要集中在间日疟,卵形疟和三日疟原虫的鉴定分型上.以省级疟疾参比实验室确诊结果为标准,市(州)级疟疾实验室共误判72份,但未出现漏诊判定.确诊的374份疟疾阳性样本均由境外国家输入,其中94.39％来自非洲,5.08％来自亚洲,0.53％来自大洋洲.结论 应持续加强全省各市(州)级疟疾实验室检测能力,特别是针对卵形疟原虫和三日疟原虫的镜检鉴定水平提升,提高检测准确率,巩固湖北全省消除疟疾成果.

OBJECTIVETo understand the current status of paragonimiasis epidemic in western mountain areas in Hubei Province.METHODSFour counties (cities) of Western Hubei Province (Xingshan, Enshi, Yunxi, Baokang) were selected as the investigation sites for active surveillance. Crabs were captured and the metacercariae of Paragonimus were detected. Meanwhile, the blood samples were collected from the residents in the surveillance sites and the unique IgG and IgM antibodies against Paragonimus in the sera were detected by ELISA. In addition, a questionnaire survey about knowledge and behavior of prevention and control of paragonimiasis was taken among the residents.RESULTSA total of 1 143 residents were investigated in the active surveillance, the total positive rate of the serology test was 1.84% (21/1 143), while the rates of the male and the female were 1.78% (10/562) and 1.89% (11/581), respectively, with no statistical significance between them ( χ2 = 0.002, P > 0.05). The average weight of 161 fresh-water crabs captured was 11.72 g, with the positive rate of 9.32% (15/161) and the infective density of 7.07 metacercariae per positive crab. The positive rates of the male and female crabs were 11.54% (9/78) and 7.23% (6/83), respectively ( χ2 = 0.884, P > 0.05), and the infective densities were 6.67 and 7.67 metacercariae per positive crab, respectively. Totally 1 143 residents were investigated by questionnaires, and 0.44% of them had the behavior of eating raw or half-done fresh-water crab, and 0.87% of them had the behavior of drinking un-boiled stream water.CONCLUSIONSThe transmission chain of paragonimiasis still exists in the nature environment of mountain area in Western Hubei Province. The positive rate of the second intermediate host rebounds in some investigation sites. Therefore, the measures of continuous surveillance and health education should be taken to avoid the appearance of the prevalence or outbreak.

Objective To understand the impact of construction of the Three Gorges Project on the paragonimiasis in Xingshan county.Methods Four epidemiological surveys including sero-epidemiologic investigation and the metacercaria of Paragonimus from crabs captured were carried out in 2012-2016.The data of the paragonimiasis before the construction and the beginning of the construction and the water storage period were collected.Results The active surveillance was conducted on 1 128 residents and the total positive rate of serology test was 2.57％(29/1 128),while the Nanyang town had the highest rate of 8.12％(25/308)with statistical significance(χ2=64.313,P=0.000).All of the three hundred and forty fresh-water crabs were captured and the positive rate was 27.94％(95/340),while the Gufu town had the highest rate of 48.80％(61/125)with statistical significance(χ2=22.942,P=0.000).The infection rates of the crabs before and after the construction were higher than the beginning of the construction period.This account had statistical significance(χ2=11.348,P=0.003).The positive rate of the serology tests cannot be compared because of the different detection technology.Conclusion The infection rate of the crabs was still high,and new area of high infection rate appeared in Xingshan because of the Three Gorges Project.Measures on continuous surveillance and health education should be taken to avoid the occurrence of outbreak.

OBJECTIVE:To predict the incidence of local malaria of Hubei Province applying the Autoregressive Integrated Moving Average model (ARIMA).METHODS:SPSS 13.0 software was applied to construct the ARIMA model based on the monthly local malaria incidence in Hubei Province from 2004 to 2009. The local malaria incidence data of 2010 were used for model validation and evaluation.RESULTS:The model of ARIMA (1, 1, 1) (1, 1, 0)12 was tested as relatively the best optimal with the AIC of 76.085 and SBC of 84.395. All the actual incidence data were in the range of 95% CI of predicted value of the model. The prediction effect of the model was acceptable.CONCLUSIONS:The ARIMA model could effectively fit and predict the incidence of local malaria of Hubei Province.

目的 评价巢式聚合酶链反应(Nested--polymerase chain reaction,nested-PCR)在输入性卵形疟诊断和分型中的应用价值.方法 采用巢式PCR方法回顾性检测湖北省2013年7月至2015年6月网报疟疾病例,比较疟疾快速诊断试剂盒(Rapid diagnostic tests,RDTs)、显微镜镜检和巢式PCR这三种方法对输入性疟疾的检测效果.结果 巢式PCR共检出卵形疟24例,其中经典亚种10例,变异亚种14例;RDTs阳性13例,阴性11例;显微镜检15例诊断为卵形疟,8例为间日疟,1例为三日疟.卵形疟两亚种在RDTs诊断阳性率和镜检准确率差异无统计学意义(P＞0.05).结论 巢式PCR在输入性卵形疟的诊断和分型上较RDTs和镜检法有显著优势.

OBJECTIVE:To understand the malaria epidemic situation in Hubei Province from 2010 to 2014, so as to provide the evidence for formulating the effective malaria elimination strategies and measures in this province.METHODS:The data from the Disease Reporting Information System of Chinese Center for Disease Control and Prevention were collected and analyzed with the descriptive epidemiological method for the epidemiological characteristics of malaria in Hubei Province from 2010 to 2014.RESULTS:A total of 997 malaria cases were reported in Hubei Province from 2010 to 2014, there were 618 cases of vivax malaria, 352 cases of falciparum malaria, 18 cases of Plasmodium ovale infection, and 9 cases of Plasmodium malariae infection. Among all the reported cases, 479 were local cases and 518 were imported cases. No local malaria cases were reported from Hubei Province since 2013. The overall imported malaria cases showed a gradual increasing trend from 2010 to 2014, the proportion of falciparum malaria increased quite significantly from 2010 to 2014. The malaria cases were mainly distributed in Xiangyang, Wuhan, Xiaogan, Yichang, Jingmen and Suizhou cities, reaching 81.85% of the cases of the whole province. There were 810 male cases and 187 female cases, with a sex ratio of 4.33:1. The local malaria cases were mainly aged from 40 to 69 years, accounted for 78.29% of the total local cases, and 88.22% (457/518) of the whole local cases were concentrated in 20-49 age groups. The local cases were mainly farmers (67.01%). Among the imported malaria cases, the occupation distribution concentrated mainly on the worker, migrant worker, and farmer (63.90%).CONCLUSIONS:The local malaria epidemic situation has been effectively controlled in Hubei Province, which reflects the initiative achievements of malaria elimination. However, there are still many imported malaria cases from abroad. Therefore, the imported malaria from abroad still remains the key of malaria control in Hubei Province.

OBJECTIVE:To explore the endemic situation of malaria in Hubei Province in 2013, so as to put forward effective elimination strategies and measures.METHODS:The data of malaria cases were searched from the Disease Reporting Information System of Chinese Center for Disease Control and Prevention and analyzed with the descriptive epidemiological method for the epidemiological characteristics of malaria in Hubei Province in 2013.RESULTS:A total of 129 malaria cases were reported in Hubei Province in 2013 with the incidence of 0.02/10,000, and all of them were imported cases, in which 86 cases with Plasmodium falciparum infection, 32 cases with P. vivax infection, 7 cases with P. ovale infection and 4 cases with P. malariae infection. The distribution of malaria cases was concentrated in Wuhan City (76 cases), Yichang City (10 cases), Xiangyang City (7 cases) and Huangshi City (6 cases), accounting for 76.74% of the total cases. There was no significant seasonal variation in the reporting time of the cases. Totally 99.22% of the cases were male, the age distribution concentrated mainly on 20-49 years. The occupation distribution concentrated mainly on the worker, farmer, cadre staff and migrant worker. The main original areas of the imported cases were Africa (111 cases, 86.05%) and Asia (17 cases, 13.18%).CONCLUSIONS:There is no local malaria cases reported in Hubei Province in 2013, however, the imported malaria cases are increased. Therefore, it is necessary to further strengthen the multi-sector collaboration of vector control, while the health education should be intensified especially in the key population.

近年来,湖北省与境外交流合作日益频繁,因流动人口引起的输人性疟疾病例逐年增加[1],因此对2012年输人性疟疾疫情进行分析,以期能为全省输入性疟疾防控提供科学依据. 1 材料与方法 1.1 资料来源 收集2012年中国疾病预防控制信息系统网络报告疫情,输人性疟疾个案调查和流行病学调查资料. 1.2 统计分析 采用描述性流行病学方法对输人性疟疾流行特征进行分析,采用Excel 2007对资料进行统计分析.

目的 了解湖北省疟疾监测点疟疾流行情况,考核防治效果.方法 采用间接荧光抗体试验(IFAT),以学龄儿童为检查对象,对5个监测点进行纵向监测,2010年增加其他疟区的4个点进行当地居民和学龄儿童的横向监测,通过疟疾抗体水平分析疟疾流行态势.结果 2006-2010年5个纵向监测点的总体疟疾抗体阳性率0.07％ ～0.73％.2010年横向监测结果只有一类疟区的枣阳和老河口各发现1例阳性.结论 湖北省疟疾监测点不同疟区的间接荧光抗体水平不同,应采取不同防治措施.